| # | Title | Journal | Year | Citations |
|---|
| 1 | OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines | Osteoarthritis and Cartilage | 2008 | 2,316 |
| 2 | OARSI guidelines for the non-surgical management of knee osteoarthritis | Osteoarthritis and Cartilage | 2014 | 2,298 |
| 3 | Osteoarthritis cartilage histopathology: grading and staging | Osteoarthritis and Cartilage | 2006 | 1,755 |
| 4 | OARSI guidelines for the non-surgical management of knee, hip, and polyarticular osteoarthritis | Osteoarthritis and Cartilage | 2019 | 1,746 |
| 5 | Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects | Osteoarthritis and Cartilage | 2002 | 1,715 |
| 6 | OARSI recommendations for the management of hip and knee osteoarthritis | Osteoarthritis and Cartilage | 2010 | 1,330 |
| 7 | Whole-Organ Magnetic Resonance Imaging Score (WORMS) of the knee in osteoarthritis | Osteoarthritis and Cartilage | 2004 | 1,242 |
| 8 | Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!) | Osteoarthritis and Cartilage | 2013 | 1,197 |
| 9 | The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the mouse | Osteoarthritis and Cartilage | 2010 | 1,151 |
| 10 | The epidemiology and impact of pain in osteoarthritis | Osteoarthritis and Cartilage | 2013 | 1,128 |
| 11 | The surgical destabilization of the medial meniscus (DMM) model of osteoarthritis in the 129/SvEv mouse | Osteoarthritis and Cartilage | 2007 | 1,053 |
| 12 | Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis | Osteoarthritis and Cartilage | 2010 | 1,051 |
| 13 | Atlas of individual radiographic features in osteoarthritis, revised | Osteoarthritis and Cartilage | 2007 | 922 |
| 14 | A meta-analysis of sex differences prevalence, incidence and severity of osteoarthritis | Osteoarthritis and Cartilage | 2005 | 861 |
| 15 | Human autologous culture expanded bone marrow mesenchymal cell transplantation for repair of cartilage defects in osteoarthritic knees | Osteoarthritis and Cartilage | 2002 | 853 |
| 16 | The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the guinea pig | Osteoarthritis and Cartilage | 2010 | 763 |
| 17 | Cellular interactions and signaling in cartilage development | Osteoarthritis and Cartilage | 2000 | 710 |
| 18 | Evolution of semi-quantitative whole joint assessment of knee OA: MOAKS (MRI Osteoarthritis Knee Score) | Osteoarthritis and Cartilage | 2011 | 690 |
| 19 | OARSI recommendations for the management of hip and knee osteoarthritis, Part I: Critical appraisal of existing treatment guidelines and systematic review of current research evidence | Osteoarthritis and Cartilage | 2007 | 685 |
| 20 | OMERACT-OARSI Initiative: Osteoarthritis Research Society International set of responder criteria for osteoarthritis clinical trials revisited. | Osteoarthritis and Cartilage | 2004 | 683 |
| 21 | Results after microfracture of full-thickness chondral defects in different compartments in the knee | Osteoarthritis and Cartilage | 2006 | 641 |
| 22 | The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review | Osteoarthritis and Cartilage | 2011 | 639 |
| 23 | The role of reactive oxygen species in homeostasis and degradation of cartilage | Osteoarthritis and Cartilage | 2003 | 629 |
| 24 | Current evidence on risk factors for knee osteoarthritis in older adults: a systematic review and meta-analysis | Osteoarthritis and Cartilage | 2015 | 621 |
| 25 | Mechanics and biology in intervertebral disc degeneration: a vicious circle | Osteoarthritis and Cartilage | 2015 | 589 |
| 26 | NF-κB as a potential therapeutic target in osteoarthritis and rheumatoid arthritis | Osteoarthritis and Cartilage | 2006 | 588 |
| 27 | Increased knee joint loads during walking are present in subjects with knee osteoarthritis | Osteoarthritis and Cartilage | 2002 | 583 |
| 28 | Chondrocyte hypertrophy and osteoarthritis: role in initiation and progression of cartilage degeneration? | Osteoarthritis and Cartilage | 2012 | 547 |
| 29 | OARSI recommended performance-based tests to assess physical function in people diagnosed with hip or knee osteoarthritis | Osteoarthritis and Cartilage | 2013 | 545 |
| 30 | The osteoarthritis initiative: report on the design rationale for the magnetic resonance imaging protocol for the knee | Osteoarthritis and Cartilage | 2008 | 539 |
| 31 | Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix | Osteoarthritis and Cartilage | 2009 | 531 |
| 32 | Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research | Osteoarthritis and Cartilage | 2012 | 520 |
| 33 | Dedifferentiation-associated changes in morphology and gene expression in primary human articular chondrocytes in cell culture | Osteoarthritis and Cartilage | 2002 | 518 |
| 34 | Design and conduct of clinical trials in patients with osteoarthritis: Recommendations from a task force of the Osteoarthritis Research Society | Osteoarthritis and Cartilage | 1996 | 512 |
| 35 | Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review | Osteoarthritis and Cartilage | 2012 | 506 |
| 36 | The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the rat | Osteoarthritis and Cartilage | 2010 | 497 |
| 37 | Do adipose tissue-derived mesenchymal stem cells have the same osteogenic and chondrogenic potential as bone marrow-derived cells? | Osteoarthritis and Cartilage | 2005 | 491 |
| 38 | Synovitis: a potential predictive factor of structural progression of medial tibiofemoral knee osteoarthritis – results of a 1 year longitudinal arthroscopic study in 422 patients | Osteoarthritis and Cartilage | 2005 | 488 |
| 39 | Exosomes derived from human embryonic mesenchymal stem cells promote osteochondral regeneration | Osteoarthritis and Cartilage | 2016 | 480 |
| 40 | Chondrogenic differentiation and functional maturation of bovine mesenchymal stem cells in long-term agarose culture | Osteoarthritis and Cartilage | 2006 | 478 |
| 41 | Osteoarthritis development in novel experimental mouse models induced by knee joint instability | Osteoarthritis and Cartilage | 2005 | 469 |
| 42 | Osteoarthritis of the knee after injury to the anterior cruciate ligament or meniscus: the influence of time and age | Osteoarthritis and Cartilage | 1995 | 467 |
| 43 | Projected increase in total knee arthroplasty in the United States – an alternative projection model | Osteoarthritis and Cartilage | 2017 | 454 |
| 44 | Osteoarthritis as a disease of mechanics | Osteoarthritis and Cartilage | 2013 | 448 |
| 45 | In vivo T1ρ and T2 mapping of articular cartilage in osteoarthritis of the knee using 3T MRI | Osteoarthritis and Cartilage | 2007 | 430 |
| 46 | Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis | Osteoarthritis and Cartilage | 2003 | 421 |
| 47 | Call for standardized definitions of osteoarthritis and risk stratification for clinical trials and clinical use | Osteoarthritis and Cartilage | 2015 | 416 |
| 48 | Quantitative structural organization of normal adult human articular cartilage | Osteoarthritis and Cartilage | 2002 | 412 |
| 49 | Knee Injury and Osteoarthritis Outcome Score (KOOS): systematic review and meta-analysis of measurement properties | Osteoarthritis and Cartilage | 2016 | 412 |
| 50 | Oxygen and reactive oxygen species in cartilage degradation: friends or foes? | Osteoarthritis and Cartilage | 2005 | 410 |
