# | Title | Journal | Year | Citations |
---|
1 | How mitochondria produce reactive oxygen species | Biochemical Journal | 2009 | 6,321 |
2 | Oxygen toxicity, oxygen radicals, transition metals and disease | Biochemical Journal | 1984 | 4,932 |
3 | Caspases: the executioners of apoptosis | Biochemical Journal | 1997 | 4,290 |
4 | Specificity and mechanism of action of some commonly used protein kinase inhibitors | Biochemical Journal | 2000 | 3,878 |
5 | Inositol trisphosphate and diacylglycerol as second messengers | Biochemical Journal | 1984 | 3,655 |
6 | Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+ | Biochemical Journal | 1995 | 3,508 |
7 | The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. Application to the radioimmunoassay | Biochemical Journal | 1973 | 3,277 |
8 | Nitric oxide synthases: structure, function and inhibition | Biochemical Journal | 2001 | 3,123 |
9 | A classification of glycosyl hydrolases based on amino acid sequence similarities | Biochemical Journal | 1991 | 2,901 |
10 | Principles of interleukin (IL)-6-type cytokine signalling and its regulation | Biochemical Journal | 2003 | 2,784 |
11 | Specificity and mechanism of action of some commonly used protein kinase inhibitors | Biochemical Journal | 2000 | 2,718 |
12 | Histone deacetylases (HDACs): characterization of the classical HDAC family | Biochemical Journal | 2003 | 2,671 |
13 | Nitric oxide synthases in mammals | Biochemical Journal | 1994 | 2,566 |
14 | Interleukin-6 and the acute phase response | Biochemical Journal | 1990 | 2,501 |
15 | Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis | Biochemical Journal | 2004 | 2,445 |
16 | Arginine metabolism: nitric oxide and beyond | Biochemical Journal | 1998 | 2,379 |
17 | The selectivity of protein kinase inhibitors: a further update | Biochemical Journal | 2007 | 2,287 |
18 | Nitric oxide synthases: structure, function and inhibition | Biochemical Journal | 2001 | 2,118 |
19 | The mitochondrial permeability transition pore and its role in cell death | Biochemical Journal | 1999 | 2,092 |
20 | Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands | Biochemical Journal | 1982 | 2,080 |
21 | Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer | Biochemical Journal | 1996 | 2,020 |
22 | Introduction to the human gut microbiota | Biochemical Journal | 2017 | 1,988 |
23 | Assessing mitochondrial dysfunction in cells | Biochemical Journal | 2011 | 1,949 |
24 | New families in the classification of glycosyl hydrolases based on amino acid sequence similarities | Biochemical Journal | 1993 | 1,939 |
25 | Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway | Biochemical Journal | 1998 | 1,895 |
26 | Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the ‘phosphocreatine circuit’ for cellular energy homeostasis | Biochemical Journal | 1992 | 1,827 |
27 | Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain | Biochemical Journal | 2000 | 1,762 |
28 | Carbohydrate-binding modules: fine-tuning polysaccharide recognition | Biochemical Journal | 2004 | 1,720 |
29 | Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics | Biochemical Journal | 1988 | 1,707 |
30 | Rho GTPases and their effector proteins | Biochemical Journal | 2000 | 1,702 |
31 | Extracellular ATP: effects, sources and fate | Biochemical Journal | 1986 | 1,636 |
32 | Recent advances in the biochemistry of polyamines in eukaryotes | Biochemical Journal | 1986 | 1,611 |
33 | Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions | Biochemical Journal | 1999 | 1,541 |
34 | The direct linear plot. A new graphical procedure for estimating enzyme kinetic parameters | Biochemical Journal | 1974 | 1,526 |
35 | Biochemistry and pathology of radical-mediated protein oxidation | Biochemical Journal | 1997 | 1,519 |
36 | Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling | Biochemical Journal | 2001 | 1,516 |
37 | The lipocalin protein family: structure and function | Biochemical Journal | 1996 | 1,505 |
38 | Sirtuins in mammals: insights into their biological function | Biochemical Journal | 2007 | 1,503 |
39 | Free-radical mechanisms in tissue injury | Biochemical Journal | 1984 | 1,489 |
40 | The extended protein kinase C superfamily | Biochemical Journal | 1998 | 1,452 |
41 | Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily | Biochemical Journal | 2001 | 1,449 |
42 | New photosensitizers for photodynamic therapy | Biochemical Journal | 2016 | 1,437 |
43 | Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria | Biochemical Journal | 1980 | 1,397 |
44 | The PI3K–PDK1 connection: more than just a road to PKB | Biochemical Journal | 2000 | 1,386 |
45 | Mechanisms and functions of p38 MAPK signalling | Biochemical Journal | 2010 | 1,342 |
46 | The specificities of protein kinase inhibitors: an update | Biochemical Journal | 2003 | 1,339 |
47 | Updating the sequence-based classification of glycosyl hydrolases | Biochemical Journal | 1996 | 1,293 |
48 | Protein kinase C isoenzymes: divergence in signal transduction? | Biochemical Journal | 1993 | 1,248 |
49 | Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling | Biochemical Journal | 2012 | 1,243 |
50 | Glucose autoxidation and protein modification. The potential role of ‘autoxidative glycosylation’ in diabetes | Biochemical Journal | 1987 | 1,228 |