3.4(top 10%)
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1.9M(top 0.1%)
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376(top 1%)
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613(top 1%)
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Top Articles

#TitleJournalYearCitations
1How mitochondria produce reactive oxygen speciesBiochemical Journal20096,572
2Oxygen toxicity, oxygen radicals, transition metals and diseaseBiochemical Journal19844,967
3Caspases: the executioners of apoptosisBiochemical Journal19974,330
4Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+Biochemical Journal19953,943
5Specificity and mechanism of action of some commonly used protein kinase inhibitorsBiochemical Journal20003,909
6Inositol trisphosphate and diacylglycerol as second messengersBiochemical Journal19843,657
7The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. Application to the radioimmunoassayBiochemical Journal19733,282
8Nitric oxide synthases: structure, function and inhibitionBiochemical Journal20013,183
9A classification of glycosyl hydrolases based on amino acid sequence similaritiesBiochemical Journal19912,927
10Principles of interleukin (IL)-6-type cytokine signalling and its regulationBiochemical Journal20032,831
11Specificity and mechanism of action of some commonly used protein kinase inhibitorsBiochemical Journal20002,728
12Histone deacetylases (HDACs): characterization of the classical HDAC familyBiochemical Journal20032,717
13Nitric oxide synthases in mammalsBiochemical Journal19942,578
14Interleukin-6 and the acute phase responseBiochemical Journal19902,522
15Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosisBiochemical Journal20042,491
16Arginine metabolism: nitric oxide and beyondBiochemical Journal19982,421
17The selectivity of protein kinase inhibitors: a further updateBiochemical Journal20072,307
18Introduction to the human gut microbiotaBiochemical Journal20172,218
19Nitric oxide synthases: structure, function and inhibitionBiochemical Journal20012,133
20The mitochondrial permeability transition pore and its role in cell deathBiochemical Journal19992,109
21Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glandsBiochemical Journal19822,082
22Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancerBiochemical Journal19962,036
23Assessing mitochondrial dysfunction in cellsBiochemical Journal20112,026
24New families in the classification of glycosyl hydrolases based on amino acid sequence similaritiesBiochemical Journal19931,948
25Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathwayBiochemical Journal19981,914
26Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the ‘phosphocreatine circuit’ for cellular energy homeostasisBiochemical Journal19921,842
27Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chainBiochemical Journal20001,806
28Carbohydrate-binding modules: fine-tuning polysaccharide recognitionBiochemical Journal20041,764
29Rho GTPases and their effector proteinsBiochemical Journal20001,720
30Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kineticsBiochemical Journal19881,711
31Extracellular ATP: effects, sources and fateBiochemical Journal19861,641
32Recent advances in the biochemistry of polyamines in eukaryotesBiochemical Journal19861,615
33Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functionsBiochemical Journal19991,570
34Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signallingBiochemical Journal20011,543
35Sirtuins in mammals: insights into their biological functionBiochemical Journal20071,538
36New photosensitizers for photodynamic therapyBiochemical Journal20161,537
37The direct linear plot. A new graphical procedure for estimating enzyme kinetic parametersBiochemical Journal19741,530
38Biochemistry and pathology of radical-mediated protein oxidationBiochemical Journal19971,528
39The lipocalin protein family: structure and functionBiochemical Journal19961,522
40Free-radical mechanisms in tissue injuryBiochemical Journal19841,494
41Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamilyBiochemical Journal20011,478
42The extended protein kinase C superfamilyBiochemical Journal19981,455
43Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondriaBiochemical Journal19801,402
44The PI3K–PDK1 connection: more than just a road to PKBBiochemical Journal20001,394
45Mechanisms and functions of p38 MAPK signallingBiochemical Journal20101,389
46The specificities of protein kinase inhibitors: an updateBiochemical Journal20031,345
47Updating the sequence-based classification of glycosyl hydrolasesBiochemical Journal19961,305
48Autophagy, mitochondria and oxidative stress: cross-talk and redox signallingBiochemical Journal20121,270
49Protein kinase C isoenzymes: divergence in signal transduction?Biochemical Journal19931,250
50Glucose autoxidation and protein modification. The potential role of ‘autoxidative glycosylation’ in diabetesBiochemical Journal19871,237