| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Nanocarriers as an emerging platform for cancer therapy | Nature Nanotechnology | 2007 | 7,609 |
| 2 | Alternative isoform regulation in human tissue transcriptomes | Nature | 2008 | 4,609 |
| 3 | DNA targeting specificity of RNA-guided Cas9 nucleases | Nature Biotechnology | 2013 | 4,085 |
| 4 | Fibroblasts in cancer | Nature Reviews Cancer | 2006 | 4,044 |
| 5 | The impact of the MIT-BIH Arrhythmia Database | IEEE Engineering in Medicine and Biology Magazine | 2001 | 3,108 |
| 6 | Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles | Molecular Pharmaceutics | 2008 | 3,064 |
| 7 | Toward discovery science of human brain function | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 2,753 |
| 8 | An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients | Breast Cancer Research and Treatment | 2010 | 2,522 |
| 9 | Hydrogels in Regenerative Medicine | Advanced Materials | 2009 | 2,379 |
| 10 | In vivo genome editing using Staphylococcus aureus Cas9 | Nature | 2015 | 2,317 |
| 11 | Widespread transcription at neuronal activity-regulated enhancers | Nature | 2010 | 2,159 |
| 12 | Advances in engineering hydrogels | Science | 2017 | 1,994 |
| 13 | Endothelial-to-mesenchymal transition contributes to cardiac fibrosis | Nature Medicine | 2007 | 1,920 |
| 14 | A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology | Cell | 2008 | 1,800 |
| 15 | Biodegradable luminescent porous silicon nanoparticles for in vivo applications | Nature Materials | 2009 | 1,752 |
| 16 | Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues | Nature Materials | 2012 | 1,698 |
| 17 | CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling | Cell | 2014 | 1,643 |
| 18 | Efficiency and power in genetic association studies | Nature Genetics | 2005 | 1,602 |
| 19 | Printing ferromagnetic domains for untethered fast-transforming soft materials | Nature | 2018 | 1,558 |
| 20 | New photosensitizers for photodynamic therapy | Biochemical Journal | 2016 | 1,537 |
| 21 | Prevalence of SARS-CoV-2 in Spain (ENE-COVID): a nationwide, population-based seroepidemiological study | Lancet, The | 2020 | 1,506 |
| 22 | Performance-optimized hierarchical models predict neural responses in higher visual cortex | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 1,489 |
| 23 | RNA editing with CRISPR-Cas13 | Science | 2017 | 1,388 |
| 24 | Programming cells by multiplex genome engineering and accelerated evolution | Nature | 2009 | 1,377 |
| 25 | Protein complexes and functional modules in molecular networks | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 1,348 |
| 26 | Analysis and design of RNA sequencing experiments for identifying isoform regulation | Nature Methods | 2010 | 1,254 |
| 27 | Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens | Cell | 2016 | 1,234 |
| 28 | Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems | Chemical Society Reviews | 2016 | 1,207 |
| 29 | Mesenchymal stem cells: immune evasive, not immune privileged | Nature Biotechnology | 2014 | 1,191 |
| 30 | 25th Anniversary Article: Rational Design and Applications of Hydrogels in Regenerative Medicine | Advanced Materials | 2014 | 1,143 |
| 31 | Advancements in Noncontact, Multiparameter Physiological Measurements Using a Webcam | IEEE Transactions on Biomedical Engineering | 2011 | 1,128 |
| 32 | The Nuts and Bolts of Low-level Laser (Light) Therapy | Annals of Biomedical Engineering | 2012 | 1,118 |
| 33 | Evolutionary dynamics on graphs | Nature | 2005 | 1,076 |
| 34 | A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers | Nature Genetics | 2006 | 1,026 |
| 35 | Biomechanics and biophysics of cancer cells☆ | Acta Biomaterialia | 2007 | 1,008 |
| 36 | SERS—a single-molecule and nanoscale tool for bioanalytics | Chemical Society Reviews | 2008 | 974 |
| 37 | The genetic architecture of type 2 diabetes | Nature | 2016 | 973 |
| 38 | Controlling the Porosity and Microarchitecture of Hydrogels for Tissue Engineering | Tissue Engineering - Part B: Reviews | 2010 | 968 |
| 39 | The Hazards of Hazard Ratios | Epidemiology | 2010 | 963 |
| 40 | Nanocomposite hydrogels for biomedical applications | Biotechnology and Bioengineering | 2014 | 954 |
| 41 | Mr contrast due to intravascular magnetic susceptibility perturbations | Magnetic Resonance in Medicine | 1995 | 934 |
| 42 | Proposed Mechanisms of Photobiomodulation or Low-Level Light Therapy | IEEE Journal of Selected Topics in Quantum Electronics | 2016 | 928 |
| 43 | Bioinks for 3D bioprinting: an overview | Biomaterials Science | 2018 | 910 |
| 44 | A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response | Cell | 2016 | 876 |
| 45 | A Functional MRI Study of Subjects Recovered From Hemiparetic Stroke | Stroke | 1997 | 871 |
| 46 | Functional assembly of engineered myocardium by electrical stimulation of cardiac myocytes cultured on scaffolds | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 844 |
| 47 | Chimaeric sounds reveal dichotomies in auditory perception | Nature | 2002 | 841 |
| 48 | Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2 | Nature | 1997 | 839 |
| 49 | How the Timing and Quality of Early Experiences Influence the Development of Brain Architecture | Child Development | 2010 | 829 |
| 50 | Emerging Frontiers in Drug Delivery | Journal of the American Chemical Society | 2016 | 813 |
