| # | Title | Journal | Year | Citations |
|---|
| 1 | International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS) | Journal of Thrombosis and Haemostasis | 2006 | 6,039 |
| 2 | Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials | BMJ: British Medical Journal | 2011 | 4,743 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 4 | Minimum information about a microarray experiment (MIAME)—toward standards for microarray data | Nature Genetics | 2001 | 3,750 |
| 5 | Tumour exosome integrins determine organotropic metastasis | Nature | 2015 | 3,688 |
| 6 | EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update | Annals of the Rheumatic Diseases | 2017 | 3,366 |
| 7 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 8 | Spatial partitioning of the regulatory landscape of the X-inactivation centre | Nature | 2012 | 2,595 |
| 9 | International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: Report of an International workshop | Arthritis and Rheumatism | 1999 | 2,512 |
| 10 | The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma | American Journal of Surgical Pathology | 2005 | 2,334 |
| 11 | Genomic correlates of response to CTLA-4 blockade in metastatic melanoma | Science | 2015 | 2,275 |
| 12 | Decreased Catecholamine Sensitivity and β-Adrenergic-Receptor Density in Failing Human Hearts | New England Journal of Medicine | 1982 | 2,271 |
| 13 | Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology | Epilepsia | 2017 | 2,191 |
| 14 | Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: Consensus Statement of the European Atherosclerosis Society | European Heart Journal | 2013 | 2,132 |
| 15 | Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017 | JAMA Surgery | 2017 | 2,099 |
| 16 | Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU | Critical Care Medicine | 2018 | 2,074 |
| 17 | The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells | Cell | 2002 | 1,897 |
| 18 | The diagnostic odds ratio: a single indicator of test performance | Journal of Clinical Epidemiology | 2003 | 1,880 |
| 19 | EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update | Annals of the Rheumatic Diseases | 2020 | 1,860 |
| 20 | Predictors of Hospital Mortality in the Global Registry of Acute Coronary Events | Archives of Internal Medicine | 2003 | 1,856 |
| 21 | A Randomized Trial Comparing Conventional and Endovascular Repair of Abdominal Aortic Aneurysms | New England Journal of Medicine | 2004 | 1,853 |
| 22 | Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer | Nature | 2017 | 1,806 |
| 23 | Functional impact of global rare copy number variation in autism spectrum disorders | Nature | 2010 | 1,803 |
| 24 | The Clinical Assessment, Treatment, and Prevention of Lyme Disease, Human Granulocytic Anaplasmosis, and Babesiosis: Clinical Practice Guidelines by the Infectious Diseases Society of America | Clinical Infectious Diseases | 2006 | 1,795 |
| 25 | Psoriasis | Lancet, The | 2015 | 1,793 |
| 26 | How brains beware: neural mechanisms of emotional attention | Trends in Cognitive Sciences | 2005 | 1,755 |
| 27 | Antiphospholipid syndrome: Clinical and immunologic manifestations and patterns of disease expression in a cohort of 1,000 patients | Arthritis and Rheumatism | 2002 | 1,736 |
| 28 | Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease | Nature Genetics | 2011 | 1,708 |
| 29 | Diffusion-Weighted Magnetic Resonance Imaging as a Cancer Biomarker: Consensus and Recommendations | Neoplasia | 2009 | 1,703 |
| 30 | EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update | Annals of the Rheumatic Diseases | 2014 | 1,688 |
| 31 | Competency-based medical education: theory to practice | Medical Teacher | 2010 | 1,649 |
| 32 | Multiorgan and Renal Tropism of SARS-CoV-2 | New England Journal of Medicine | 2020 | 1,523 |
| 33 | Consensus on women’s health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group | Fertility and Sterility | 2012 | 1,494 |
| 34 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 35 | The HSP70 chaperone machinery: J proteins as drivers of functional specificity | Nature Reviews Molecular Cell Biology | 2010 | 1,423 |
| 36 | Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial | Lancet Oncology, The | 2015 | 1,419 |
| 37 | The global burden of mental disorders: An update from the WHO World Mental Health (WMH) Surveys | Epidemiologia E Psichiatria Sociale | 2009 | 1,412 |
| 38 | Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress | Nature | 2002 | 1,399 |
| 39 | Linking Colorectal Cancer to Wnt Signaling | Cell | 2000 | 1,386 |
| 40 | Multicellular tumor spheroids: An underestimated tool is catching up again | Journal of Biotechnology | 2010 | 1,376 |
| 41 | A Step-up Approach or Open Necrosectomy for Necrotizing Pancreatitis | New England Journal of Medicine | 2010 | 1,358 |
| 42 | Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a randomised, multicentre, open-label, phase 3 non-inferiority trial | Lancet Oncology, The | 2014 | 1,356 |
| 43 | Long-term air pollution exposure and cardio- respiratory mortality: a review | Environmental Health | 2013 | 1,346 |
| 44 | AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1 | Nature | 2000 | 1,335 |
| 45 | Routine Use of the Confusion Assessment Method for the Intensive Care Unit | American Journal of Respiratory and Critical Care Medicine | 2011 | 1,318 |
| 46 | 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus | Annals of the Rheumatic Diseases | 2019 | 1,265 |
| 47 | The Impact of Critical Illness on Perceived Health-Related Quality of Life During ICU Treatment, Hospital Stay, and After Hospital Discharge | Chest | 2008 | 1,260 |
| 48 | Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy | Nature | 2016 | 1,243 |
| 49 | Evidence-based guidelines on the therapeutic use of transcranial direct current stimulation (tDCS) | Clinical Neurophysiology | 2017 | 1,213 |
| 50 | Management of Abdominal Aortic Aneurysms Clinical Practice Guidelines of the European Society for Vascular Surgery | European Journal of Vascular and Endovascular Surgery | 2011 | 1,204 |
