| # | Title | Journal | Year | Citations |
|---|
| 1 | Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial | Lancet, The | 2008 | 1,333 |
| 2 | Sepsis and the systemic inflammatory response syndrome | Critical Care Medicine | 1996 | 832 |
| 3 | European Resuscitation Council Guidelines for Resuscitation 2015 | Resuscitation | 2015 | 696 |
| 4 | DemTect: a new, sensitive cognitive screening test to support the diagnosis of mild cognitive impairment and early dementia | International Journal of Geriatric Psychiatry | 2004 | 668 |
| 5 | Incremental Support Vector Learning for Ordinal Regression | IEEE Transactions on Neural Networks and Learning Systems | 2015 | 659 |
| 6 | An assessment of nonconvulsive seizures in the intensive care unit using continuous EEG monitoring | Neurology | 1996 | 636 |
| 7 | Interaction of citrus juices with felodipine and nifedipine | Lancet, The | 1991 | 594 |
| 8 | Peripheral nerve regeneration and neurotrophic factors | Journal of Anatomy | 1999 | 586 |
| 9 | CRITICAL ILLNESS POLYNEUROPATHY | Brain | 1987 | 544 |
| 10 | ν-Support Vector Regression">Incremental learning for ν-Support Vector Regression | Neural Networks | 2015 | 473 |
| 11 | Conversion of amyloid positive and negative MCI to AD over 3 years | Neurology | 2009 | 469 |
| 12 | A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study to Evaluate the Safety and Efficacy of Recombinant Human Soluble Thrombomodulin, ART-123, in Patients With Sepsis and Suspected Disseminated Intravascular Coagulation* | Critical Care Medicine | 2013 | 423 |
| 13 | Validation of a 6 item cognitive impairment test with a view to primary care usage | International Journal of Geriatric Psychiatry | 1999 | 419 |
| 14 | Mild cognitive impairment and deficits in instrumental activities of daily living: a systematic review | Alzheimer's Research and Therapy | 2015 | 419 |
| 15 | A guide to biological skin substitutes | Journal of Plastic, Reconstructive and Aesthetic Surgery | 2002 | 401 |
| 16 | Randomised trial of oral morphine for chronic non-cancer pain | Lancet, The | 1996 | 397 |
| 17 | European Resuscitation Council Guidelines 2021: Cardiac arrest in special circumstances | Resuscitation | 2021 | 364 |
| 18 | A kinematic analysis of reaching and grasping movements in a patient recovering from optic ataxia | Neuropsychologia | 1991 | 339 |
| 19 | Increased nerve growth factor levels in the urinary bladder of women with idiopathic sensory urgency and interstitial cystitis | BJU International | 1997 | 337 |
| 20 | Electrocardiographic Changes Simulating Myocardial Ischemia and Infarction Associated with Spontaneous Intracranial Hemorrhage | Circulation | 1960 | 331 |
| 21 | Neuropsychiatric Syndromes in Dementia | Dementia and Geriatric Cognitive Disorders | 2007 | 305 |
| 22 | The role of endogenous nerve growth factor in human diabetic neuropathy | Nature Medicine | 1996 | 299 |
| 23 | A Hypothesis: The Protein Catabolic Rate is Dependent Upon the Type and Amount of Treatment in Dialyzed Uremic Patients | American Journal of Kidney Diseases | 1989 | 283 |
| 24 | Prognostic value of neurohumoral activation in patients with an acute myocardial infarction: Effect of captopril | Journal of the American College of Cardiology | 1994 | 274 |
| 25 | Biochemical and Metabolic Abnormalities in Articular Cartilage from Osteo-arthritic Human Hips. II: Correlation of Morphology with Biochemical and Metabolic Data | | 2014 | 269 |
| 26 | Prevalence and epidemiology of toenail onychomycosis in diabetic subjects: a multicentre survey | British Journal of Dermatology | 1998 | 267 |
| 27 | High-sensitivity troponin in the evaluation of patients with suspected acute coronary syndrome: a stepped-wedge, cluster-randomised controlled trial | Lancet, The | 2018 | 263 |
| 28 | Misled by the Wedge? | Chest | 1986 | 252 |
| 29 | European Resuscitation Council Guidelines 2021: Newborn resuscitation and support of transition of infants at birth | Resuscitation | 2021 | 251 |
| 30 | Incidence and phenotypes of childhood-onset genetic epilepsies: a prospective population-based national cohort | Brain | 2019 | 248 |
| 31 | Pain assessment in osteoarthritis: Experience with the WOMAC osteoarthritis index | Seminars in Arthritis and Rheumatism | 1989 | 247 |
| 32 | Vascular cognitive disorder: a new diagnostic category updating vascular cognitive impairment and vascular dementia | Journal of the Neurological Sciences | 2004 | 242 |
| 33 | A Role for Corticosteroid-Binding Globulin in Delivery of Cortisol to Activated Neutrophils* | Journal of Clinical Endocrinology and Metabolism | 1990 | 240 |
| 34 | Small cell carcinoma of the urinary bladder. A clinicopathologic analysis of 22 cases | Cancer | 1992 | 236 |
| 35 | Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone‐refractory prostate cancer | Cancer | 2008 | 230 |
| 36 | Splenic trauma: WSES classification and guidelines for adult and pediatric patients | World Journal of Emergency Surgery | 2017 | 230 |
| 37 | RELATION OF REDUCTION IN PRESSURE TO FIRST MYOCARDIAL INFARCTION IN PATIENTS RECEIVING TREATMENT FOR SEVERE HYPERTENSION | Lancet, The | 1979 | 226 |
| 38 | Grapefruit juice–felodipine interaction: Mechanism, predictability, and effect of naringin | Clinical Pharmacology and Therapeutics | 1993 | 223 |
| 39 | Expression of HLA antigens, β2-microglobulin and enzymes by human amniotic epithelial cells | Nature | 1982 | 222 |
| 40 | Does the pulmonary capillary wedge pressure predict left ventricular preload in critically ill patients? | Critical Care Medicine | 1981 | 221 |
| 41 | Clinical effectiveness of transversus abdominis plane (TAP) block in abdominal surgery: a systematic review and meta‐analysis | Colorectal Disease | 2012 | 218 |
| 42 | Hepatitis B in sub-Saharan Africa: strategies to achieve the 2030 elimination targets | The Lancet Gastroenterology and Hepatology | 2017 | 217 |
| 43 | Epidemiology and Treatment of Chronic Bronchitis and Its Exacerbations | Chest | 1995 | 213 |
| 44 | Rivastigmine and donepezil treatment in moderate to moderately-severe Alzheimer's disease over a 2-year period | Current Medical Research and Opinion | 2005 | 212 |
| 45 | Statins for the prevention of dementia | The Cochrane Library | 2016 | 212 |
| 46 | Rising incidence of pediatric inflammatory bowel disease in Scotland* | Inflammatory Bowel Diseases | 2012 | 208 |
| 47 | Outcomes and DNA analysis of ex vivo expanded stem cell allograft for ocular surface reconstruction | Ophthalmology | 2005 | 201 |
| 48 | Acute necrotizing myopathy of intensive care: Electrophysiological studies | Muscle and Nerve | 1994 | 200 |
| 49 | Increase in microvascular permeability induced by enzymatically generated free radicals | Microvascular Research | 1981 | 192 |
| 50 | A retrospective review of a large cohort of patients undergoing the process of withholding or withdrawal of life support | Critical Care Medicine | 1997 | 192 |
