| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | The Brazilian health system: history, advances, and challenges | Lancet, The | 2011 | 1,500 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 4 | The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication | Frontiers in Endocrinology | 2020 | 1,235 |
| 5 | Sexual problems among women and men aged 40–80 y: prevalence and correlates identified in the Global Study of Sexual Attitudes and Behaviors | International Journal of Impotence Research | 2005 | 1,167 |
| 6 | Global Morbidity and Mortality of Leptospirosis: A Systematic Review | PLoS Neglected Tropical Diseases | 2015 | 1,134 |
| 7 | A 9-Valent HPV Vaccine against Infection and Intraepithelial Neoplasia in Women | New England Journal of Medicine | 2015 | 1,090 |
| 8 | Cancer survival in five continents: a worldwide population-based study (CONCORD) | Lancet Oncology, The | 2008 | 1,059 |
| 9 | Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: a cohort study | Lancet Infectious Diseases, The | 2014 | 1,039 |
| 10 | Urinary, Circulating, and Tissue Biomonitoring Studies Indicate Widespread Exposure to Bisphenol A | Environmental Health Perspectives | 2010 | 1,038 |
| 11 | First report of autochthonous transmission of Zika virus in Brazil | Memorias Do Instituto Oswaldo Cruz | 2015 | 1,005 |
| 12 | Detection and sequencing of Zika virus from amniotic fluid of fetuses with microcephaly in Brazil: a case study | Lancet Infectious Diseases, The | 2016 | 981 |
| 13 | Chronic non-communicable diseases in Brazil: burden and current challenges | Lancet, The | 2011 | 979 |
| 14 | Efficacy of Quadrivalent HPV Vaccine against HPV Infection and Disease in Males | New England Journal of Medicine | 2011 | 955 |
| 15 | Wound healing - A literature review | Anais Brasileiros De Dermatologia | 2016 | 905 |
| 16 | Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples | Nature Protocols | 2017 | 898 |
| 17 | Zika virus in the Americas: Early epidemiological and genetic findings | Science | 2016 | 877 |
| 18 | Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection | JAMA Network Open | 2020 | 842 |
| 19 | HPV Vaccine against Anal HPV Infection and Anal Intraepithelial Neoplasia | New England Journal of Medicine | 2011 | 810 |
| 20 | Emtricitabine-Tenofovir Concentrations and Pre-Exposure Prophylaxis Efficacy in Men Who Have Sex with Men | Science Translational Medicine | 2012 | 807 |
| 21 | Ticks and tick-borne diseases: a One Health perspective | Trends in Parasitology | 2012 | 802 |
| 22 | The revised Trypanosoma cruzi subspecific nomenclature: Rationale, epidemiological relevance and research applications | Infection, Genetics and Evolution | 2012 | 728 |
| 23 | Indigenous and tribal peoples' health (The Lancet–Lowitja Institute Global Collaboration): a population study | Lancet, The | 2016 | 682 |
| 24 | Maternal and child health in Brazil: progress and challenges | Lancet, The | 2011 | 677 |
| 25 | ORIGINAL ARTICLES: Definitions/Epidemiology/Risk Factors for Sexual Dysfunction | Journal of Sexual Medicine | 2010 | 655 |
| 26 | Urban epidemic of severe leptospirosis in Brazil | Lancet, The | 1999 | 624 |
| 27 | Safety and efficacy of the HIV-1 integrase inhibitor raltegravir (MK-0518) in treatment-experienced patients with multidrug-resistant virus: a phase II randomised controlled trial | Lancet, The | 2007 | 580 |
| 28 | Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis | Critical Care | 2007 | 580 |
| 29 | Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19 | Blood | 2020 | 576 |
| 30 | Origins of Dengue Type 2 Viruses Associated with Increased Pathogenicity in the Americas | Virology | 1997 | 557 |
| 31 | TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis | Journal of Experimental Medicine | 2005 | 532 |
| 32 | Leptospirosis | Current Opinion in Infectious Diseases | 2005 | 522 |
| 33 | Antibody evasion by the P.1 strain of SARS-CoV-2 | Cell | 2021 | 519 |
| 34 | Brazil's unified health system: the first 30 years and prospects for the future | Lancet, The | 2019 | 515 |
| 35 | Activation of Toll-Like Receptor-2 by Glycosylphosphatidylinositol Anchors from a Protozoan Parasite | Journal of Immunology | 2001 | 513 |
| 36 | The 2019‐new coronavirus epidemic: Evidence for virus evolution | Journal of Medical Virology | 2020 | 508 |
| 37 | Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer | Cell Death and Differentiation | 2016 | 506 |
| 38 | Sexual behavior and sexual dysfunctions after age 40: The global study of sexual attitudes and behaviors | Urology | 2004 | 505 |
| 39 | Contemporary status of insecticide resistance in the major Aedes vectors of arboviruses infecting humans | PLoS Neglected Tropical Diseases | 2017 | 504 |
| 40 | Differential Susceptibilities of Aedes aegypti and Aedes albopictus from the Americas to Zika Virus | PLoS Neglected Tropical Diseases | 2016 | 499 |
| 41 | The political origins of health inequity: prospects for change | Lancet, The | 2014 | 497 |
| 42 | Leishmaniases of the New World: current concepts and implications for future research | Clinical Microbiology Reviews | 1993 | 496 |
| 43 | Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes | Science | 2015 | 492 |
| 44 | Dengue Virus Capsid Protein Usurps Lipid Droplets for Viral Particle Formation | PLoS Pathogens | 2009 | 484 |
| 45 | Components of plastic: experimental studies in animals and relevance for human health | Philosophical Transactions of the Royal Society B: Biological Sciences | 2009 | 484 |
| 46 | A Cross-National Study of Subjective Sexual Well-Being Among Older Women and Men: Findings From the Global Study of Sexual Attitudes and Behaviors | Archives of Sexual Behavior | 2006 | 480 |
| 47 | Management of latentMycobacterium tuberculosisinfection: WHO guidelines for low tuberculosis burden countries | European Respiratory Journal | 2015 | 475 |
| 48 | Analyzing marginal cases in differential shotgun proteomics | Bioinformatics | 2011 | 474 |
| 49 | Chagas disease: a new worldwide challenge | Nature | 2010 | 470 |
| 50 | Chagas' Disease | Circulation | 1956 | 465 |
