| # | Title | Journal | Year | Citations |
|---|
| 1 | International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS) | Journal of Thrombosis and Haemostasis | 2006 | 6,039 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension | Lancet, The | 1997 | 2,841 |
| 4 | Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial | Lancet, The | 2004 | 2,422 |
| 5 | The Effects of Strontium Ranelate on the Risk of Vertebral Fracture in Women with Postmenopausal Osteoporosis | New England Journal of Medicine | 2004 | 1,465 |
| 6 | The Study on Cognition and Prognosis in the Elderly (SCOPE) | Journal of Hypertension | 2003 | 1,251 |
| 7 | Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials | Lancet, The | 2012 | 743 |
| 8 | Affective Interactions Using Virtual Reality: The Link between Presence and Emotions | Cyberpsychology, Behavior and Social Networking | 2007 | 716 |
| 9 | EULAR recommendations for the management of antiphospholipid syndrome in adults | Annals of the Rheumatic Diseases | 2019 | 664 |
| 10 | Assessment and management of blood-pressure variability | Nature Reviews Cardiology | 2013 | 645 |
| 11 | Management of high blood pressure in children and adolescents: recommendations of the European Society of Hypertension | Journal of Hypertension | 2009 | 620 |
| 12 | EULAR recommendations for women's health and the management of family planning, assisted reproduction, pregnancy and menopause in patients with systemic lupus erythematosus and/or antiphospholipid syndrome | Annals of the Rheumatic Diseases | 2017 | 590 |
| 13 | Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture | Nature Genetics | 2013 | 578 |
| 14 | 2013 ESH/ESC Practice Guidelines for the Management of Arterial Hypertension | Blood Pressure | 2014 | 565 |
| 15 | The Past, Present, and Future of Virtual and Augmented Reality Research: A Network and Cluster Analysis of the Literature | Frontiers in Psychology | 2018 | 547 |
| 16 | Blood pressure dependent and independent effects of antihypertensive treatment on clinical events in the VALUE Trial | Lancet, The | 2004 | 540 |
| 17 | Neuroendocrine control of food intake | Nutrition, Metabolism and Cardiovascular Diseases | 2008 | 522 |
| 18 | International recommendations for the assessment of autoantibodies to cellular antigens referred to as anti-nuclear antibodies | Annals of the Rheumatic Diseases | 2014 | 471 |
| 19 | Mitochondrial biogenesis by NO yields functionally active mitochondria in mammals | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 447 |
| 20 | European Society of Hypertension Practice Guidelines for home blood pressure monitoring | Journal of Human Hypertension | 2010 | 427 |
| 21 | Self-monitoring of blood pressure in hypertension: A systematic review and individual patient data meta-analysis | PLoS Medicine | 2017 | 401 |
| 22 | X-linked Cornelia de Lange syndrome owing to SMC1L1 mutations | Nature Genetics | 2006 | 393 |
| 23 | Clinical and molecular diagnosis, screening and management of Beckwith–Wiedemann syndrome: an international consensus statement | Nature Reviews Endocrinology | 2018 | 388 |
| 24 | Virtual Reality in Psychotherapy: Review | Cyberpsychology, Behavior and Social Networking | 2005 | 366 |
| 25 | Methylation of ELOVL2 gene as a new epigenetic marker of age | Aging Cell | 2012 | 362 |
| 26 | Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document | Blood Pressure | 2009 | 351 |
| 27 | 2021 European Society of Hypertension practice guidelines for office and out-of-office blood pressure measurement | Journal of Hypertension | 2021 | 349 |
| 28 | Genome-Wide Association Study of Blood Pressure Extremes Identifies Variant near UMOD Associated with Hypertension | PLoS Genetics | 2010 | 312 |
| 29 | Systolic blood pressure variability as a risk factor for stroke and cardiovascular mortality in the elderly hypertensive population | Journal of Hypertension | 2003 | 305 |
| 30 | eHealth for Patient Engagement: A Systematic Review | Frontiers in Psychology | 2015 | 290 |
| 31 | Dynamics of complement activation in aHUS and how to monitor eculizumab therapy | Blood | 2014 | 288 |
| 32 | Aryl Hydrocarbon Receptor-Interacting Protein Gene Mutations in Familial Isolated Pituitary Adenomas: Analysis in 73 Families | Journal of Clinical Endocrinology and Metabolism | 2007 | 283 |
| 33 | Positive Technology: Using Interactive Technologies to Promote Positive Functioning | Cyberpsychology, Behavior, and Social Networking | 2012 | 277 |
| 34 | Estimated Frequency of Antiphospholipid Antibodies in Patients With Pregnancy Morbidity, Stroke, Myocardial Infarction, and Deep Vein Thrombosis: A Critical Review of the Literature | Arthritis Care and Research | 2013 | 275 |
| 35 | Response to Antihypertensive Therapy in Older Patients With Sustained and Nonsustained Systolic Hypertension | Circulation | 2000 | 271 |
| 36 | The systemic nature of CKD | Nature Reviews Nephrology | 2017 | 265 |
| 37 | TNF- downregulates eNOS expression and mitochondrial biogenesis in fat and muscle of obese rodents | Journal of Clinical Investigation | 2006 | 265 |
| 38 | Growth hormone in obesity | International Journal of Obesity | 1999 | 254 |
| 39 | Clinical Presentation and Outcome in a Contemporary Cohort of Patients With Acute Myocarditis | Circulation | 2018 | 253 |
| 40 | Relation between blood pressure variability and carotid artery damage in hypertension: baseline data from the European Lacidipine Study on Atherosclerosis (ELSA) | Journal of Hypertension | 2001 | 246 |
| 41 | When should antihypertensive drug treatment be initiated and to what levels should systolic blood pressure be lowered? A critical reappraisal | Journal of Hypertension | 2009 | 243 |
| 42 | Psychological Consequences of Social Isolation During COVID-19 Outbreak | Frontiers in Psychology | 2020 | 238 |
| 43 | Virtual Reality Training for Health-Care Professionals | Cyberpsychology, Behavior and Social Networking | 2003 | 233 |
| 44 | Cardiovascular disease in autoimmune rheumatic diseases | Autoimmunity Reviews | 2013 | 232 |
| 45 | Differences in quadriceps muscle strength and fatigue between lean and obese subjects | European Journal of Applied Physiology | 2007 | 229 |
| 46 | Treatment With Multiple Blood Pressure Medications, Achieved Blood Pressure, and Mortality in Older Nursing Home Residents | JAMA Internal Medicine | 2015 | 225 |
| 47 | C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activation | Nature Communications | 2016 | 224 |
| 48 | Reproducibility and clinical value of nocturnal hypotension | Journal of Hypertension | 1998 | 222 |
| 49 | Mutations in the Small GTPase Gene RAB39B Are Responsible for X-linked Mental Retardation Associated with Autism, Epilepsy, and Macrocephaly | American Journal of Human Genetics | 2010 | 220 |
| 50 | Clinical Characterization of Familial Isolated Pituitary Adenomas | Journal of Clinical Endocrinology and Metabolism | 2006 | 217 |
