| # | Title | Journal | Year | Citations |
|---|
| 1 | International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma | European Respiratory Journal | 2014 | 2,898 |
| 2 | Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial | Lancet, The | 2010 | 2,002 |
| 3 | Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study | Lancet, The | 2009 | 1,918 |
| 4 | Intra-abdominal hypertension and the abdominal compartment syndrome: updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome | Intensive Care Medicine | 2013 | 1,197 |
| 5 | Association analysis identifies 65 new breast cancer risk loci | Nature | 2017 | 1,099 |
| 6 | Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial | Lancet Neurology, The | 2008 | 971 |
| 7 | Critical Care Services and 2009 H1N1 Influenza in Australia and New Zealand | New England Journal of Medicine | 2009 | 920 |
| 8 | Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial | Lancet, The | 2011 | 849 |
| 9 | A placental clock controlling the length of human pregnancy | Nature Medicine | 1995 | 847 |
| 10 | Inflammatory subtypes in asthma: Assessment and identification using induced sputum | Respirology | 2006 | 787 |
| 11 | Treatable traits: toward precision medicine of chronic airway diseases | European Respiratory Journal | 2016 | 746 |
| 12 | A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome) | Nature Genetics | 1998 | 654 |
| 13 | Self-management education and regular practitioner review for adults with asthma | The Cochrane Library | 2002 | 624 |
| 14 | Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study | Diabetes | 2009 | 575 |
| 15 | The overlap syndrome of asthma and COPD: what are its features and how important is it? | Thorax | 2009 | 513 |
| 16 | Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20 | Nature Genetics | 2009 | 501 |
| 17 | Heterogeneity of Airway Inflammation in Persistent Asthma | Chest | 2001 | 484 |
| 18 | A systematic review of potential long-term effects of sport-related concussion | British Journal of Sports Medicine | 2017 | 457 |
| 19 | COVID ‐19 acute respiratory distress syndrome ( ARDS ): clinical features and differences from typical pre‐ COVID ‐19 ARDS | Medical Journal of Australia | 2020 | 441 |
| 20 | The Effect of CPAP in Normalizing Daytime Sleepiness, Quality of Life, and Neurocognitive Function in Patients with Moderate to Severe OSA | Sleep | 2011 | 436 |
| 21 | The independent predictive utility of computed tomography angiographic collateral status in acute ischaemic stroke | Brain | 2009 | 423 |
| 22 | SLC34A3 Mutations in Patients with Hereditary Hypophosphatemic Rickets with Hypercalciuria Predict a Key Role for the Sodium-Phosphate Cotransporter NaPi-IIc in Maintaining Phosphate Homeostasis | American Journal of Human Genetics | 2006 | 422 |
| 23 | Clinical course, therapeutic responses and outcomes in relapsing MOG antibody-associated demyelination | Journal of Neurology, Neurosurgery and Psychiatry | 2018 | 422 |
| 24 | Parturition | New England Journal of Medicine | 2007 | 415 |
| 25 | Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function | Nature Communications | 2016 | 412 |
| 26 | Antagonism of microRNA-126 suppresses the effector function of T H 2 cells and the development of allergic airways disease | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 401 |
| 27 | Incidents relating to the intra-hospital transfer of critically ill patients | Intensive Care Medicine | 2004 | 387 |
| 28 | Progesterone Withdrawal and Estrogen Activation in Human Parturition Are Coordinated by Progesterone Receptor A Expression in the Myometrium | Journal of Clinical Endocrinology and Metabolism | 2002 | 361 |
| 29 | Written action plans for asthma: an evidence-based review of the key components | Thorax | 2004 | 354 |
| 30 | Exhaled Nitric Oxide in Pulmonary Diseases | Chest | 2010 | 347 |
| 31 | Association of Initial Disease-Modifying Therapy With Later Conversion to Secondary Progressive Multiple Sclerosis | JAMA - Journal of the American Medical Association | 2019 | 336 |
| 32 | Neutrophil degranulation and cell lysis is associated with clinical severity in virus-induced asthma | European Respiratory Journal | 2002 | 331 |
| 33 | Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders | American Journal of Human Genetics | 2018 | 326 |
| 34 | Extending thrombolysis to 4·5–9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data | Lancet, The | 2019 | 321 |
| 35 | The Impact of Service-Specific Staffing, Case Scheduling, Turnovers, and First-Case Starts on Anesthesia Group and Operating Room Productivity: A Tutorial Using Data from an Australian Hospital | Anesthesia and Analgesia | 2006 | 305 |
| 36 | A novel X-linked trichothiodystrophy associated with a nonsense mutation in RNF113A | Journal of Medical Genetics | 2015 | 302 |
| 37 | Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study | Diabetes Care | 2012 | 295 |
| 38 | Innate immune activation in neutrophilic asthma and bronchiectasis | Thorax | 2007 | 290 |
| 39 | Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer | Nature Genetics | 2017 | 289 |
| 40 | Dynamin GTPase regulated by protein kinase C phosphorylation in nerve terminals | Nature | 1993 | 284 |
| 41 | Effect of Aspirin or Resistant Starch on Colorectal Neoplasia in the Lynch Syndrome | New England Journal of Medicine | 2008 | 273 |
| 42 | Anti-inflammatory effect of itraconazole in stable allergic bronchopulmonary aspergillosis: A randomized controlled trial | Journal of Allergy and Clinical Immunology | 2003 | 269 |
| 43 | Knowledge of Stroke Risk Factors, Warning Symptoms, and Treatment Among an Australian Urban Population | Stroke | 2001 | 265 |
| 44 | Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2017 update of the evidence-based guidelines from the world society of emergency surgery ASBO working group | World Journal of Emergency Surgery | 2018 | 265 |
| 45 | Array CGH identifies reciprocal 16p13.1 duplications and deletions that predispose to autism and/or mental retardation | Human Mutation | 2007 | 263 |
| 46 | Treatment of Unexplained Chronic Cough | Chest | 2016 | 263 |
| 47 | C-reactive protein: A critical review | Pathology | 1991 | 261 |
| 48 | The Efficacy of Transforaminal Injection of Steroids for the Treatment of Lumbar Radicular Pain | Pain Medicine | 2010 | 259 |
| 49 | Cyclic GMP‐Dependent Protein Kinase and Cellular Signaling in the Nervous System | Journal of Neurochemistry | 1997 | 254 |
| 50 | Biomarkers of lipid peroxidation, airway inflammation and asthma | European Respiratory Journal | 2003 | 254 |
