| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | SARS and MERS: recent insights into emerging coronaviruses | Nature Reviews Microbiology | 2016 | 2,752 |
| 3 | PROTOFIBRILS, PORES, FIBRILS, ANDNEURODEGENERATION: Separating the Responsible Protein Aggregates from The Innocent Bystanders | Annual Review of Neuroscience | 2003 | 1,574 |
| 4 | Effects of CCR5 and CD4 Cell Surface Concentrations on Infections by Macrophagetropic Isolates of Human Immunodeficiency Virus Type 1 | Journal of Virology | 1998 | 1,152 |
| 5 | Ebola haemorrhagic fever | Lancet, The | 2011 | 1,101 |
| 6 | Cell-free formation of protease-resistant prion protein | Nature | 1994 | 859 |
| 7 | Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy | Biochemistry | 1991 | 822 |
| 8 | Staphylococcal Biofilms | Current Topics in Microbiology and Immunology | 2008 | 749 |
| 9 | The scrapie-associated form of PrP is made from a cell surface precursor that is both protease- and phospholipase-sensitive. | Journal of Biological Chemistry | 1991 | 547 |
| 10 | Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain | Nature | 1985 | 494 |
| 11 | RNAIII-Independent Target Gene Control by the agr Quorum-Sensing System: Insight into the Evolution of Virulence Regulation in Staphylococcus aureus | Molecular Cell | 2008 | 489 |
| 12 | A Crucial Role for Exopolysaccharide Modification in Bacterial Biofilm Formation, Immune Evasion, and Virulence | Journal of Biological Chemistry | 2004 | 480 |
| 13 | The scrapie-associated form of PrP is made from a cell surface precursor that is both protease- and phospholipase-sensitive | Journal of Biological Chemistry | 1991 | 476 |
| 14 | Heterogeneity of Major Proteins in Lyme Disease Borreliae: A Molecular Analysis of North American and European Isolates | Journal of Infectious Diseases | 1985 | 442 |
| 15 | Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV–infected rhesus macaques | Nature Medicine | 2013 | 412 |
| 16 | Compensatory ahpC Gene Expression in Isoniazid-Resistant Mycobacterium tuberculosis | Science | 1996 | 411 |
| 17 | Linear plasmids of the bacterium Borrelia burgdorferi have covalently closed ends | Science | 1987 | 401 |
| 18 | Noncanonical Inflammasome Activation of Caspase-4/Caspase-11 Mediates Epithelial Defenses against Enteric Bacterial Pathogens | Cell Host and Microbe | 2014 | 371 |
| 19 | Silver Coordination Polymers for Prevention of Implant Infection: Thiol Interaction, Impact on Respiratory Chain Enzymes, and Hydroxyl Radical Induction | Antimicrobial Agents and Chemotherapy | 2010 | 359 |
| 20 | Middle East Respiratory Syndrome Coronavirus Infection in Dromedary Camels in Saudi Arabia | MBio | 2014 | 359 |
| 21 | Mapping antigenic domains expressed by Chlamydia trachomatis major outer membrane protein genes. | Proceedings of the National Academy of Sciences of the United States of America | 1988 | 358 |
| 22 | Chlamydial disease pathogenesis. The 57-kD chlamydial hypersensitivity antigen is a stress response protein. | Journal of Experimental Medicine | 1989 | 356 |
| 23 | Lipid metabolism in Chlamydia trachomatis-infected cells: directed trafficking of Golgi-derived sphingolipids to the chlamydial inclusion. | Proceedings of the National Academy of Sciences of the United States of America | 1995 | 354 |
| 24 | Dissemination of invasiveSalmonellavia bacterial-induced extrusion of mucosal epithelia | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 354 |
| 25 | From The Cover: A chlamydial type III translocated protein is tyrosine-phosphorylated at the site of entry and associated with recruitment of actin | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 351 |
| 26 | Stationary phase-associated protein expression in Mycobacterium tuberculosis: function of the mycobacterial alpha-crystallin homolog | Journal of Bacteriology | 1996 | 309 |
| 27 | Prion protein biosynthesis in scrapie-infected and uninfected neuroblastoma cells | Journal of Virology | 1989 | 301 |
| 28 | Autosomal dominant and sporadic monocytopenia with susceptibility to mycobacteria, fungi, papillomaviruses, and myelodysplasia | Blood | 2010 | 299 |
| 29 | Bat-borne virus diversity, spillover and emergence | Nature Reviews Microbiology | 2020 | 298 |
| 30 | Neisseria gonorrhoeae acquires mutations in analogous regions of gyrA and parC in fluoroquinolone‐resistant isolates | Molecular Microbiology | 1994 | 297 |
| 31 | Strain-dependent Differences in β-Sheet Conformations of Abnormal Prion Protein | Journal of Biological Chemistry | 1998 | 292 |
| 32 | Temporal Analysis of Coxiella burnetii Morphological Differentiation | Journal of Bacteriology | 2004 | 277 |
| 33 | Simplified ultrasensitive prion detection by recombinant PrP conversion with shaking | Nature Methods | 2008 | 273 |
| 34 | Inhibition of Interferon-Stimulated JAK-STAT Signaling by a Tick-Borne Flavivirus and Identification of NS5 as an Interferon Antagonist | Journal of Virology | 2005 | 272 |
| 35 | Role of the Accessory Gene Regulator agr in Community-Associated Methicillin-Resistant Staphylococcus aureus Pathogenesis | Infection and Immunity | 2011 | 272 |
| 36 | The antimicrobial peptide‐sensing system aps of Staphylococcus aureus | Molecular Microbiology | 2007 | 271 |
| 37 | Transposition of structural genes to an expression sequence on a linear plasmid causes antigenic variation in the bacterium Borrelia hermsii | Nature | 1985 | 269 |
| 38 | Human Babesiosis on Nantucket Island, USA: Description of the Vector, Ixodes (Ixodes) Dammini, N. Sp. (Acarina: Ixodidae)1 | Journal of Medical Entomology | 1979 | 268 |
| 39 | Prions and their partners in crime | Nature | 2006 | 265 |
| 40 | Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance | Science | 2014 | 262 |
| 41 | A Specific and Sensitive Assay for the Lyme Disease Spirochete Borrelia burgdorferi Using the Polymerase Chain Reaction | Journal of Infectious Diseases | 1989 | 259 |
| 42 | Molecular assessment of the potential transmissibilities of BSE and scrapie to humans | Nature | 1997 | 259 |
| 43 | Salmonella- the ultimate insider.Salmonellavirulence factors that modulate intracellular survival | Cellular Microbiology | 2009 | 259 |
| 44 | The Salmonella-containing vacuole—Moving with the times | Current Opinion in Microbiology | 2008 | 258 |
| 45 | The B Cell Receptor Governs the Subcellular Location of Toll-like Receptor 9 Leading to Hyperresponses to DNA-Containing Antigens | Immunity | 2008 | 255 |
| 46 | Gram-positive three-component antimicrobial peptide-sensing system | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 254 |
| 47 | Inhibition of novel β coronavirus replication by a combination of interferon-α2b and ribavirin | Scientific Reports | 2013 | 250 |
| 48 | The Western Black-Legged Tick, Ixodes Pacificus: A Vector of Borrelia Burgdorferi | American Journal of Tropical Medicine and Hygiene | 1985 | 247 |
| 49 | Characterization of monoclonal antibodies reactive with murine leukemia viruses: Use in analysis of strains of friend MCF and friend ecotropic murine leukemia virus | Virology | 1983 | 245 |
| 50 | Conversion of raft associated prion protein to the protease-resistant state requires insertion of PrP-res (PrPSc) into contiguous membranes | EMBO Journal | 2002 | 241 |
