| # | Title | Journal | Year | Citations |
|---|
| 1 | Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America Guidelines for Developing an Institutional Program to Enhance Antimicrobial Stewardship | Clinical Infectious Diseases | 2007 | 3,390 |
| 2 | Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the Intensive Care Unit | Critical Care Medicine | 2013 | 3,066 |
| 3 | The Actor–Partner Interdependence Model: A model of bidirectional effects in developmental studies | International Journal of Behavioral Development | 2005 | 1,360 |
| 4 | The elephant in uremia: Oxidant stress as a unifying concept of cardiovascular disease in uremia | Kidney International | 2002 | 1,012 |
| 5 | Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma | JAMA - Journal of the American Medical Association | 2015 | 982 |
| 6 | Prospective evaluation of the Sedation-Agitation Scale for adult critically ill patients | Critical Care Medicine | 1999 | 887 |
| 7 | Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase | Science | 1991 | 779 |
| 8 | Incidence and Mortality of Acute Renal Failure in Medicare Beneficiaries, 1992 to 2001 | Journal of the American Society of Nephrology: JASN | 2006 | 671 |
| 9 | Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease | Kidney International | 2004 | 629 |
| 10 | Temporal trends in the treatment of over 1.5 million patients with myocardial infarction in the U.S. from 1990 through 1999 | Journal of the American College of Cardiology | 2000 | 610 |
| 11 | Assessing sedation during intensive care unit mechanical ventilation with the Bispectral Index and the Sedation-Agitation Scale | Critical Care Medicine | 1999 | 606 |
| 12 | Outcomes of Patients with Differentiated Thyroid Carcinoma Following Initial Therapy | Thyroid | 2006 | 593 |
| 13 | Mutations in ENPP1 are associated with 'idiopathic' infantile arterial calcification | Nature Genetics | 2003 | 539 |
| 14 | A recurrent 16p12.1 microdeletion supports a two-hit model for severe developmental delay | Nature Genetics | 2010 | 539 |
| 15 | Antimicrobial‐Associated Risk Factors forClostridium difficileInfection | Clinical Infectious Diseases | 2008 | 531 |
| 16 | Partner effects in relationship research: Conceptual issues, analytic difficulties, and illustrations | Personal Relationships | 1999 | 519 |
| 17 | IOM Committee Members Respond to Endocrine Society Vitamin D Guideline | Journal of Clinical Endocrinology and Metabolism | 2012 | 492 |
| 18 | Phenylalanine hydroxylase deficiency: diagnosis and management guideline | Genetics in Medicine | 2014 | 486 |
| 19 | Variation in Carotid Endarterectomy Mortality in the Medicare Population | JAMA - Journal of the American Medical Association | 1998 | 477 |
| 20 | FAMILY PSYCHOEDUCATION AND SCHIZOPHRENIA: A REVIEW OF THE LITERATURE | Journal of Marital and Family Therapy | 2003 | 407 |
| 21 | Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy in the Management of Peritoneal Surface Malignancies of Colonic Origin: A Consensus Statement | Annals of Surgical Oncology | 2007 | 390 |
| 22 | Assessing the Quality of Decision Support Technologies Using the International Patient Decision Aid Standards instrument (IPDASi) | PLoS ONE | 2009 | 374 |
| 23 | Lowest hematocrit on bypass and adverse outcomes associated with coronary artery bypass grafting | Annals of Thoracic Surgery | 2001 | 350 |
| 24 | Antimicrobial Safety: Focus on Fluoroquinolones | Clinical Infectious Diseases | 2005 | 349 |
| 25 | Prospective multicenter study of thyroid carcinoma treatment | | 1998 | 347 |
| 26 | Consensus Summary Statement of the International Multidisciplinary Consensus Conference on Multimodality Monitoring in Neurocritical Care | Neurocritical Care | 2014 | 339 |
| 27 | Interhospital Transfer Before Thrombectomy Is Associated With Delayed Treatment and Worse Outcome in the STRATIS Registry (Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke) | Circulation | 2017 | 332 |
| 28 | Microduplication 22q11.2, an Emerging Syndrome: Clinical, Cytogenetic, and Molecular Analysis of Thirteen Patients | American Journal of Human Genetics | 2003 | 327 |
| 29 | Cardio-Oncology | Circulation Research | 2016 | 313 |
| 30 | Subsyndromal delirium in the ICU: evidence for a disease spectrum | Intensive Care Medicine | 2007 | 307 |
| 31 | Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 303 |
| 32 | Parental Smoking and Adolescent Smoking Initiation: An Intergenerational Perspective on Tobacco Control | Pediatrics | 2009 | 301 |
| 33 | Temporal Trends in the Utilization of Diagnostic Testing and Treatments for Cardiovascular Disease in the United States, 1993–2001 | Circulation | 2006 | 299 |
| 34 | Viscosity of normal human blood under normothermic and hypothermic conditions | Journal of Applied Physiology | 1964 | 297 |
| 35 | A composite view of cardiac rupture in the United States national registry of myocardial infarction | Journal of the American College of Cardiology | 1996 | 289 |
| 36 | Race and Surgical Mortality in the United States | Annals of Surgery | 2006 | 286 |
| 37 | Spontaneous Platelet Activation and Aggregation During Obstructive Sleep Apnea and Its Response to Therapy With Nasal Continuous Positive Airway Pressure | Chest | 1995 | 285 |
| 38 | Varieties of Uncertainty in Health Care: A Conceptual Taxonomy | Medical Decision Making | 2011 | 282 |
| 39 | Increased Expression of Estrogen Receptor-β mRNA in Male Blood Vessels After Vascular Injury | Circulation Research | 1998 | 280 |
| 40 | Continuous infusion of haloperidol controls agitation in critically ill patients | Critical Care Medicine | 1994 | 276 |
| 41 | A prospective randomized multi-center study for the treatment of lumbar spinal stenosis with the X STOP interspinous implant: 1-year results | European Spine Journal | 2004 | 275 |
| 42 | Generalized Arterial Calcification of Infancy and Pseudoxanthoma Elasticum Can Be Caused by Mutations in Either ENPP1 or ABCC6 | American Journal of Human Genetics | 2012 | 274 |
| 43 | Diabetic and Nondiabetic Patients With Left Main and/or 3-Vessel Coronary Artery Disease | Journal of the American College of Cardiology | 2010 | 271 |
| 44 | The Significance of Platelets with Increased RNA Content (Reticulated Platelets) A Measure of the Rate of Thrombopoiesis | American Journal of Clinical Pathology | 1992 | 270 |
| 45 | Duration of Acute Kidney Injury Impacts Long-Term Survival After Cardiac Surgery | Annals of Thoracic Surgery | 2010 | 268 |
| 46 | Validating the Sedation-Agitation Scale with the Bispectral Index and Visual Analog Scale in adult ICU patients after cardiac surgery | Intensive Care Medicine | 2001 | 262 |
| 47 | A multicenter, U.S. experience of single-balloon, double-balloon, and rotational overtube–assisted enteroscopy ERCP in patients with surgically altered pancreaticobiliary anatomy (with video) | Gastrointestinal Endoscopy | 2013 | 259 |
| 48 | Consensus summary statement of the International Multidisciplinary Consensus Conference on Multimodality Monitoring in Neurocritical Care | Intensive Care Medicine | 2014 | 258 |
| 49 | Relation Between Operator and Hospital Volume and Outcomes Following Percutaneous Coronary Interventions in the Era of the Coronary Stent | JAMA - Journal of the American Medical Association | 2000 | 257 |
| 50 | Tolerance of uncertainty: Conceptual analysis, integrative model, and implications for healthcare | Social Science and Medicine | 2017 | 254 |
