| Mild cognitive impairment--beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment | Journal of Internal Medicine | 2004 | 3.3K |
| Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 2004 | 2.4K |
| Pathways towards and away from Alzheimer's disease | Nature | 2004 | 2.3K |
| Enhancing treatment fidelity in health behavior change studies: best practices and recommendations from the NIH Behavior Change Consortium | Health Psychology | 2004 | 1.5K |
| Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia | Blood | 2004 | 950 |
| The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 888 |
| Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 791 |
| The genetic association database | Nature Genetics | 2004 | 754 |
| Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore | Journal of Clinical Investigation | 2004 | 741 |
| Designing randomized, controlled trials aimed at preventing or delaying functional decline and disability in frail, older persons: a consensus report | Journal of the American Geriatrics Society | 2004 | 709 |
| Dynamics of global gene expression changes during mouse preimplantation development | Developmental Cell | 2004 | 698 |
| BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders | Trends in Neurosciences | 2004 | 690 |
| Differences between human and mouse embryonic stem cells | Developmental Biology | 2004 | 590 |
| Inflammatory markers and physical performance in older persons: the InCHIANTI study | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 2004 | 582 |
| Nestin expression--a property of multi-lineage progenitor cells? | Cellular and Molecular Life Sciences | 2004 | 519 |
| SOX2, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult | Developmental Neuroscience | 2004 | 516 |
| Multiple roles of antimicrobial defensins, cathelicidins, and eosinophil-derived neurotoxin in host defense | Annual Review of Immunology | 2004 | 465 |
| Identification of a target RNA motif for RNA-binding protein HuR | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 414 |
| Foxl2 disruption causes mouse ovarian failure by pervasive blockage of follicle development | Human Molecular Genetics | 2004 | 412 |
| Marital status, marital transitions, and health: a gendered life course perspective | Journal of Health and Social Behavior | 2004 | 411 |
| The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) | Genome Research | 2004 | 404 |
| Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs | EMBO Journal | 2004 | 403 |
| Age-associated alteration of gene expression patterns in mouse oocytes | Human Molecular Genetics | 2004 | 395 |
| Anemia is associated with disability and decreased physical performance and muscle strength in the elderly | Journal of the American Geriatrics Society | 2004 | 380 |
| RyR2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca2+ release (SOICR) | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 356 |
