| # | Title | Journal | Year | Citations |
|---|
| 1 | The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease | Alzheimer's and Dementia | 2011 | 12,681 |
| 2 | The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics | Science | 2002 | 12,113 |
| 3 | A simple technique for quantitation of low levels of DNA damage in individual cells | Experimental Cell Research | 1988 | 9,283 |
| 4 | The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease | Alzheimer's and Dementia | 2011 | 7,498 |
| 5 | A Short Physical Performance Battery Assessing Lower Extremity Function: Association With Self-Reported Disability and Prediction of Mortality and Nursing Home Admission | Journal of Gerontology | 1994 | 7,145 |
| 6 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 7 | Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease | Alzheimer's and Dementia | 2011 | 5,550 |
| 8 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 9 | An Introduction to the Five-Factor Model and Its Applications | Journal of Personality | 1992 | 4,657 |
| 10 | A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity | Science | 2007 | 3,884 |
| 11 | Resveratrol improves health and survival of mice on a high-calorie diet | Nature | 2006 | 3,882 |
| 12 | -Synuclein Locus Triplication Causes Parkinson's Disease | Science | 2003 | 3,836 |
| 13 | A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD | Neuron | 2011 | 3,833 |
| 14 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
| 15 | Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease | Nature Genetics | 2013 | 3,741 |
| 16 | Lower-Extremity Function in Persons over the Age of 70 Years as a Predictor of Subsequent Disability | New England Journal of Medicine | 1995 | 3,381 |
| 17 | Biological, clinical and population relevance of 95 loci for blood lipids | Nature | 2010 | 3,249 |
| 18 | Rapamycin fed late in life extends lifespan in genetically heterogeneous mice | Nature | 2009 | 3,191 |
| 19 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 20 | Personality trait structure as a human universal. | American Psychologist | 1997 | 2,852 |
| 21 | Next-generation genotype imputation service and methods | Nature Genetics | 2016 | 2,828 |
| 22 | Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease | Nature Genetics | 2009 | 2,697 |
| 23 | Discovery and refinement of loci associated with lipid levels | Nature Genetics | 2013 | 2,641 |
| 24 | Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index | Nature Genetics | 2010 | 2,634 |
| 25 | Sarcopenia: An Undiagnosed Condition in Older Adults. Current Consensus Definition: Prevalence, Etiology, and Consequences. International Working Group on Sarcopenia | Journal of the American Medical Directors Association | 2011 | 2,427 |
| 26 | A reference panel of 64,976 haplotypes for genotype imputation | Nature Genetics | 2016 | 2,421 |
| 27 | PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin | PLoS Biology | 2010 | 2,299 |
| 28 | Longitudinal Effects of Aging on Serum Total and Free Testosterone Levels in Healthy Men | Journal of Clinical Endocrinology and Metabolism | 2001 | 2,275 |
| 29 | Lower Extremity Function and Subsequent Disability: Consistency Across Studies, Predictive Models, and Value of Gait Speed Alone Compared With the Short Physical Performance Battery | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 2000 | 2,264 |
| 30 | Chronic inflammation in the etiology of disease across the life span | Nature Medicine | 2019 | 2,195 |
| 31 | Cloning of the Gene Containing Mutations that Cause PARK8-Linked Parkinson's Disease | Neuron | 2004 | 2,183 |
| 32 | Cellular response to oxidative stress: Signaling for suicide and survival | Journal of Cellular Physiology | 2002 | 2,053 |
| 33 | National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach | Acta Neuropathologica | 2012 | 2,002 |
| 34 | New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk | Nature Genetics | 2010 | 1,982 |
| 35 | National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease | Alzheimer's and Dementia | 2012 | 1,968 |
| 36 | Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Nature Genetics | 2019 | 1,962 |
| 37 | Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises | Circulation | 2003 | 1,925 |
| 38 | Histone H4-K16 Acetylation Controls Chromatin Structure and Protein Interactions | Science | 2006 | 1,881 |
| 39 | Two Shorter Forms of the CES-D Depression Symptoms Index | Journal of Aging and Health | 1993 | 1,864 |
| 40 | Current Methods in Medical Image Segmentation | Annual Review of Biomedical Engineering | 2000 | 1,820 |
| 41 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 42 | Hundreds of variants clustered in genomic loci and biological pathways affect human height | Nature | 2010 | 1,789 |
| 43 | Genome-wide association study reveals genetic risk underlying Parkinson's disease | Nature Genetics | 2009 | 1,745 |
| 44 | Geroscience: Linking Aging to Chronic Disease | Cell | 2014 | 1,709 |
| 45 | Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease | Nature Genetics | 2011 | 1,708 |
| 46 | Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease | Nature Genetics | 2011 | 1,685 |
| 47 | Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease | Nature Genetics | 2014 | 1,685 |
| 48 | Gadd153 Sensitizes Cells to Endoplasmic Reticulum Stress by Down-Regulating Bcl2 and Perturbing the Cellular Redox State | Molecular and Cellular Biology | 2001 | 1,678 |
| 49 | Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia | Science | 2008 | 1,654 |
| 50 | The FNIH Sarcopenia Project: Rationale, Study Description, Conference Recommendations, and Final Estimates | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 2014 | 1,638 |
