| # | Title | Journal | Year | Citations |
|---|
| 1 | Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial | Lancet, The | 2019 | 1,625 |
| 2 | Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study | Lancet, The | 2016 | 1,414 |
| 3 | Prognostic value of grip strength: findings from the Prospective Urban Rural Epidemiology (PURE) study | Lancet, The | 2015 | 1,295 |
| 4 | First-line nivolumab plus chemotherapy versus chemotherapy alone for advanced gastric, gastro-oesophageal junction, and oesophageal adenocarcinoma (CheckMate 649): a randomised, open-label, phase 3 trial | Lancet, The | 2021 | 1,237 |
| 5 | Modifiable risk factors, cardiovascular disease, and mortality in 155 722 individuals from 21 high-income, middle-income, and low-income countries (PURE): a prospective cohort study | Lancet, The | 2020 | 935 |
| 6 | Positive biodiversity-productivity relationship predominant in global forests | Science | 2016 | 864 |
| 7 | Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study | Lancet, The | 2017 | 841 |
| 8 | The effect of physical activity on mortality and cardiovascular disease in 130 000 people from 17 high-income, middle-income, and low-income countries: the PURE study | Lancet, The | 2017 | 838 |
| 9 | Use of secondary prevention drugs for cardiovascular disease in the community in high-income, middle-income, and low-income countries (the PURE Study): a prospective epidemiological survey | Lancet, The | 2011 | 803 |
| 10 | Cardiovascular Risk and Events in 17 Low-, Middle-, and High-Income Countries | New England Journal of Medicine | 2014 | 679 |
| 11 | Mapping tree density at a global scale | Nature | 2015 | 642 |
| 12 | Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas | Nature Genetics | 2013 | 564 |
| 13 | Efficacy of apixaban when compared with warfarin in relation to renal function in patients with atrial fibrillation: insights from the ARISTOTLE trial | European Heart Journal | 2012 | 491 |
| 14 | Refractive error study in children: results from Shunyi District, China | American Journal of Ophthalmology | 2000 | 486 |
| 15 | A review on the state-of-the-art of physical/chemical and biological technologies for biogas upgrading | Reviews in Environmental Science and Biotechnology | 2015 | 468 |
| 16 | Hepatic Helicobacter species identified in bile and gallbladder tissue from chileans with chronic cholecystitis | Gastroenterology | 1998 | 455 |
| 17 | Fruit, vegetable, and legume intake, and cardiovascular disease and deaths in 18 countries (PURE): a prospective cohort study | Lancet, The | 2017 | 446 |
| 18 | Nitrification with high nitrite accumulation for the treatment of wastewater with high ammonia concentration | Water Research | 2003 | 438 |
| 19 | Variations in common diseases, hospital admissions, and deaths in middle-aged adults in 21 countries from five continents (PURE): a prospective cohort study | Lancet, The | 2020 | 428 |
| 20 | Rivaroxaban with or without aspirin in patients with stable coronary artery disease: an international, randomised, double-blind, placebo-controlled trial | Lancet, The | 2018 | 426 |
| 21 | Refractive error study in children: results from La Florida, Chile | American Journal of Ophthalmology | 2000 | 394 |
| 22 | Dulaglutide and renal outcomes in type 2 diabetes: an exploratory analysis of the REWIND randomised, placebo-controlled trial | Lancet, The | 2019 | 394 |
| 23 | Phase III, randomised trial of avelumab versus physician’s choice of chemotherapy as third-line treatment of patients with advanced gastric or gastro-oesophageal junction cancer: primary analysis of JAVELIN Gastric 300 | Annals of Oncology | 2018 | 387 |
| 24 | Model Predictive Control: MPC's Role in the Evolution of Power Electronics | IEEE Industrial Electronics Magazine | 2015 | 383 |
| 25 | Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies | Lancet, The | 2016 | 381 |
| 26 | The 2010–2015 megadrought in central Chile: impacts on regional hydroclimate and vegetation | Hydrology and Earth System Sciences | 2017 | 368 |
| 27 | Tools for Sequence-Based miRNA Target Prediction: What to Choose? | International Journal of Molecular Sciences | 2016 | 353 |
| 28 | Refractive error study in children: results from Mechi Zone, Nepal | American Journal of Ophthalmology | 2000 | 351 |
| 29 | Socioeconomic status and risk of cardiovascular disease in 20 low-income, middle-income, and high-income countries: the Prospective Urban Rural Epidemiologic (PURE) study | The Lancet Global Health | 2019 | 340 |
| 30 | The KEYNOTE-811 trial of dual PD-1 and HER2 blockade in HER2-positive gastric cancer | Nature | 2021 | 335 |
| 31 | Acknowledging the use of human cadaveric tissues in research papers: Recommendations from anatomical journal editors | Clinical Anatomy | 2021 | 302 |
| 32 | Safety of Proton Pump Inhibitors Based on a Large, Multi-Year, Randomized Trial of Patients Receiving Rivaroxaban or Aspirin | Gastroenterology | 2019 | 299 |
| 33 | Consumer Attitudes Towards Environmental Concerns of Meat Consumption: A Systematic Review | International Journal of Environmental Research and Public Health | 2019 | 299 |
| 34 | Association of dairy intake with cardiovascular disease and mortality in 21 countries from five continents (PURE): a prospective cohort study | Lancet, The | 2018 | 295 |
| 35 | Malondialdehyde: Facts and Artifacts | Plant Physiology | 2019 | 294 |
| 36 | Availability, affordability, and consumption of fruits and vegetables in 18 countries across income levels: findings from the Prospective Urban Rural Epidemiology (PURE) study | The Lancet Global Health | 2016 | 287 |
| 37 | Analysis of Finite-Control-Set Model Predictive Current Control With Model Parameter Mismatch in a Three-Phase Inverter | IEEE Transactions on Industrial Electronics | 2016 | 284 |
| 38 | Co-benefits of addressing climate change can motivate action around the world | Nature Climate Change | 2016 | 272 |
| 39 | Availability and affordability of cardiovascular disease medicines and their effect on use in high-income, middle-income, and low-income countries: an analysis of the PURE study data | Lancet, The | 2016 | 272 |
| 40 | Silver nanoparticles: Toxicity in model organisms as an overview of its hazard for human health and the environment | Journal of Hazardous Materials | 2020 | 266 |
| 41 | Epidemiology of esophageal adenocarcinoma | Journal of Surgical Oncology | 2005 | 257 |
| 42 | Global mortality variations in patients with heart failure: results from the International Congestive Heart Failure (INTER-CHF) prospective cohort study | The Lancet Global Health | 2017 | 247 |
| 43 | Urinary sodium excretion, blood pressure, cardiovascular disease, and mortality: a community-level prospective epidemiological cohort study | Lancet, The | 2018 | 243 |
| 44 | Extremozymes: A Potential Source for Industrial Applications | Journal of Microbiology and Biotechnology | 2017 | 237 |
| 45 | Regular black holes with a nonlinear electrodynamics source | Physical Review D | 2014 | 230 |
| 46 | Promoting healthy movement behaviours among children during the COVID-19 pandemic | The Lancet Child and Adolescent Health | 2020 | 228 |
| 47 | Glomalin-related soil protein in a Mediterranean ecosystem affected by a copper smelter and its contribution to Cu and Zn sequestration | Science of the Total Environment | 2008 | 218 |
| 48 | Potentials of anaerobic membrane bioreactors to overcome treatment limitations induced by industrial wastewaters | Bioresource Technology | 2012 | 217 |
| 49 | Isolation of culturable phosphobacteria with both phytate-mineralization and phosphate-solubilization activity from the rhizosphere of plants grown in a volcanic soil | Biology and Fertility of Soils | 2008 | 211 |
| 50 | Enzymes as useful tools for environmental purposes | Chemosphere | 2014 | 211 |
