| # | Title | Journal | Year | Citations |
|---|
| 1 | Overall efficacy of HPV-16/18 AS04-adjuvanted vaccine against grade 3 or greater cervical intraepithelial neoplasia: 4-year end-of-study analysis of the randomised, double-blind PATRICIA trial | Lancet Oncology, The | 2012 | 584 |
| 2 | Correlation between inclination of the acetabular component and metal ion levels in metal-on-metal hip resurfacing replacement | Journal of Bone and Joint Surgery: British Volume | 2008 | 440 |
| 3 | Mutations in the Small GTP-ase Late Endosomal Protein RAB7 Cause Charcot-Marie-Tooth Type 2B Neuropathy | American Journal of Human Genetics | 2003 | 415 |
| 4 | Metal Ion Measurement as a Diagnostic Tool to Identify Problems with Metal-on-Metal Hip Resurfacing | Journal of Bone and Joint Surgery - Series A | 2008 | 302 |
| 5 | Combining epigenetic drugs with other therapies for solid tumours — past lessons and future promise | Nature Reviews Clinical Oncology | 2020 | 283 |
| 6 | Exercise-Induced Hypoalgesia in Pain-Free and Chronic Pain Populations: State of the Art and Future Directions | Journal of Pain | 2019 | 238 |
| 7 | Intermittent versus continuous renal replacement therapy for acute kidney injury patients admitted to the intensive care unit: results of a randomized clinical trial | Nephrology Dialysis Transplantation | 2009 | 232 |
| 8 | A 10-Year Prospective Study of Sensorineural Hearing Loss in Children with Congenital Cytomegalovirus Infection | Journal of Pediatrics | 2008 | 207 |
| 9 | Revision of metal-on-metal resurfacing arthroplasty of the hip | Journal of Bone and Joint Surgery: British Volume | 2008 | 202 |
| 10 | Prospective, Risk-Adapted Strategy of Stereotactic Body Radiotherapy for Early-Stage Non–Small-Cell Lung Cancer: Results of a Phase II Trial | International Journal of Radiation Oncology Biology Physics | 2011 | 176 |
| 11 | Buttonhole needling of haemodialysis arteriovenous fistulae results in less complications and interventions compared to the rope-ladder technique | Nephrology Dialysis Transplantation | 2010 | 168 |
| 12 | Conformal Arc Radiotherapy for Prostate Cancer: Increased Biochemical Failure in Patients With Distended Rectum on the Planning Computed Tomogram Despite Image Guidance by Implanted Markers | International Journal of Radiation Oncology Biology Physics | 2009 | 155 |
| 13 | Current approaches in dendritic cell generation and future implications for cancer immunotherapy | Cancer Immunology, Immunotherapy | 2007 | 149 |
| 14 | Euthanasia requests, procedures and outcomes for 100 Belgian patients suffering from psychiatric disorders: a retrospective, descriptive study | BMJ Open | 2015 | 141 |
| 15 | Renal replacement therapy is an independent risk factor for mortality in critically ill patients with acute kidney injury | Critical Care | 2010 | 140 |
| 16 | Brain-derived neurotrophic factor as a driving force behind neuroplasticity in neuropathic and central sensitization pain: a new therapeutic target? | Expert Opinion on Therapeutic Targets | 2015 | 137 |
| 17 | Human exposure to endocrine disrupting chemicals and fertility: A case–control study in male subfertility patients | Environment International | 2015 | 136 |
| 18 | Understanding the nature of psychiatric comorbidity in migraine: a systematic review focused on interactions and treatment implications | Journal of Headache and Pain | 2019 | 127 |
| 19 | Nutrition in Pediatric Inflammatory Bowel Disease | Journal of Pediatric Gastroenterology and Nutrition | 2018 | 121 |
| 20 | Identification and validation of biomarkers of persistent acute kidney injury: the RUBY study | Intensive Care Medicine | 2020 | 120 |
| 21 | 2019 EACTS/EACTA/EBCP guidelines on cardiopulmonary bypass in adult cardiac surgery | British Journal of Anaesthesia | 2019 | 116 |
| 22 | A randomized assessor-blind trial comparing highly purified hMG and recombinant FSH in a GnRH antagonist cycle with compulsory single-blastocyst transfer | Fertility and Sterility | 2012 | 113 |
| 23 | Recommendations for neonatologist performed echocardiography in Europe: Consensus Statement endorsed by European Society for Paediatric Research (ESPR) and European Society for Neonatology (ESN) | Pediatric Research | 2016 | 113 |
| 24 | Why do patients with ischemic cardiomyopathy and a substantial amount of viable myocardium not always recover in function after revascularization? | Journal of Thoracic and Cardiovascular Surgery | 2004 | 103 |
| 25 | Sleep disturbances and severe stress as glial activators: key targets for treating central sensitization in chronic pain patients? | Expert Opinion on Therapeutic Targets | 2017 | 95 |
| 26 | Application of Neonatologist Performed Echocardiography in the assessment of a patent ductus arteriosus | Pediatric Research | 2018 | 95 |
| 27 | Multicentric parallel phase II trial of the polo-like kinase 1 inhibitor BI 2536 in patients with advanced head and neck cancer, breast cancer, ovarian cancer, soft tissue sarcoma and melanoma. The first protocol of the European Organization for Research and Treatment of Cancer (EORTC) Network Of Core Institutes (NOCI) | European Journal of Cancer | 2010 | 94 |
| 28 | Treatment of central sensitization in patients with ‘unexplained’ chronic pain: what options do we have? | Expert Opinion on Pharmacotherapy | 2011 | 94 |
| 29 | Treatment of central sensitization in patients with chronic pain: time for change? | Expert Opinion on Pharmacotherapy | 2019 | 94 |
| 30 | Prescription of inhalers in asthma and COPD: Towards a rational, rapid and effective approach | Respiratory Medicine | 2013 | 87 |
| 31 | TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis | Human Mutation | 2017 | 87 |
| 32 | Determination of free thyroid hormones | Best Practice and Research in Clinical Endocrinology and Metabolism | 2013 | 84 |
| 33 | Nociception Affects Motor Output | Clinical Journal of Pain | 2012 | 83 |
| 34 | A synbiotic-containing amino-acid-based formula improves gut microbiota in non-IgE-mediated allergic infants | Pediatric Research | 2018 | 76 |
| 35 | Delayed immune-related adverse events with anti-PD-1-based immunotherapy in melanoma | Annals of Oncology | 2021 | 76 |
| 36 | Rezafungin Versus Caspofungin in a Phase 2, Randomized, Double-blind Study for the Treatment of Candidemia and Invasive Candidiasis: The STRIVE Trial | Clinical Infectious Diseases | 2021 | 75 |
| 37 | The αE-catenin gene (CTNNA1) acts as an invasion-suppressor gene in human colon cancer cells | Oncogene | 1999 | 73 |
| 38 | HLA-G Expression in Human Embryonic Stem Cells and Preimplantation Embryos | Journal of Immunology | 2011 | 73 |
| 39 | Efficacy of the HPV-16/18 AS04-Adjuvanted Vaccine Against Low-Risk HPV Types (PATRICIA Randomized Trial): An Unexpected Observation | Journal of Infectious Diseases | 2013 | 73 |
| 40 | Decreased in vivo availability of the cannabinoid type 2 receptor in Alzheimer’s disease | European Journal of Nuclear Medicine and Molecular Imaging | 2016 | 69 |
| 41 | Malfunctioning of the autonomic nervous system in patients with chronic fatigue syndrome: a systematic literature review | European Journal of Clinical Investigation | 2014 | 67 |
| 42 | Intracranial artery dissection | European Journal of Neurology | 2014 | 63 |
| 43 | Uveitis-like syndrome and iris transillumination after the use of oral moxifloxacin | Eye | 2009 | 62 |
| 44 | The hybrid approach for the surgical treatment of lone atrial fibrillation: One-year results employing a monopolar radiofrequency source | Journal of Cardiothoracic Surgery | 2012 | 61 |
| 45 | Meta‐analysis for the effect of medical therapy vs. Placebo on recovery of idiopathic sudden hearing loss | Laryngoscope | 2010 | 60 |
| 46 | Malignancy and Mortality in Pediatric Patients with Inflammatory Bowel Disease | Inflammatory Bowel Diseases | 2014 | 60 |
| 47 | Durable clinical benefit with nivolumab (NIVO) plus low-dose ipilimumab (IPI) as first-line therapy in microsatellite instability-high/mismatch repair deficient (MSI-H/dMMR) metastatic colorectal cancer (mCRC) | Annals of Oncology | 2018 | 60 |
| 48 | Cerebrovascular Autoregulation Monitoring in the Management of Adult Severe Traumatic Brain Injury: A Delphi Consensus of Clinicians | Neurocritical Care | 2021 | 59 |
| 49 | Decrease in uric acid in acute ischemic stroke correlates with stroke severity, evolution and outcome | Clinical Chemistry and Laboratory Medicine | 2010 | 57 |
| 50 | 2019 EACTS/EACTA/EBCP guidelines on cardiopulmonary bypass in adult cardiac surgery | European Journal of Cardio-thoracic Surgery | 2020 | 57 |
