| # | Title | Journal | Year | Citations |
|---|
| 1 | New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1) | European Journal of Cancer | 2009 | 21,739 |
| 2 | Improved Survival with Ipilimumab in Patients with Metastatic Melanoma | New England Journal of Medicine | 2010 | 13,065 |
| 3 | The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data | Cancer Discovery | 2012 | 12,801 |
| 4 | Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal | Science Signaling | 2013 | 11,344 |
| 5 | 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer | Thyroid | 2016 | 10,674 |
| 6 | Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation | New England Journal of Medicine | 2011 | 6,976 |
| 7 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 8 | Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer | Science | 2015 | 6,756 |
| 9 | The Cancer Genome Atlas Pan-Cancer analysis project | Nature Genetics | 2013 | 6,265 |
| 10 | Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1 | Cancer Cell | 2010 | 6,138 |
| 11 | Revised American Thyroid Association Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer | Thyroid | 2009 | 6,039 |
| 12 | The 2016 revision of the World Health Organization classification of lymphoid neoplasms | Blood | 2016 | 5,965 |
| 13 | Inferring tumour purity and stromal and immune cell admixture from expression data | Nature Communications | 2013 | 5,788 |
| 14 | Operating characteristics of a rank correlation test for publication bias | Biometrics | 1994 | 5,751 |
| 15 | Microenvironmental regulation of tumor progression and metastasis | Nature Medicine | 2013 | 5,730 |
| 16 | Sunitinib versus Interferon Alfa in Metastatic Renal-Cell Carcinoma | New England Journal of Medicine | 2007 | 5,409 |
| 17 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 18 | TGF-β SIGNAL TRANSDUCTION | Annual Review of Biochemistry | 1998 | 4,586 |
| 19 | Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel | Blood | 2017 | 4,375 |
| 20 | Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method | Cancer Research | 2010 | 4,304 |
| 21 | Prevention of Colorectal Cancer by Colonoscopic Polypectomy | New England Journal of Medicine | 1993 | 4,216 |
| 22 | Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies | Pharmacological Reviews | 2006 | 4,172 |
| 23 | Cancer nanomedicine: progress, challenges and opportunities | Nature Reviews Cancer | 2017 | 4,153 |
| 24 | International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma | Journal of Thoracic Oncology | 2011 | 4,127 |
| 25 | EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 4,106 |
| 26 | Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease | Cell | 2017 | 4,081 |
| 27 | Integrated genomic characterization of endometrial carcinoma | Nature | 2013 | 4,075 |
| 28 | Integrin Signaling | Science | 1999 | 4,053 |
| 29 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 | Cell Death and Differentiation | 2018 | 4,036 |
| 30 | The Somatic Genomic Landscape of Glioblastoma | Cell | 2013 | 3,979 |
| 31 | The Emerging Hallmarks of Cancer Metabolism | Cell Metabolism | 2016 | 3,943 |
| 32 | Tolerance of normal tissue to therapeutic irradiation | International Journal of Radiation Oncology Biology Physics | 1991 | 3,929 |
| 33 | Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy | New England Journal of Medicine | 2012 | 3,847 |
| 34 | Nivolumab plus Ipilimumab in Advanced Melanoma | New England Journal of Medicine | 2013 | 3,776 |
| 35 | Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma | New England Journal of Medicine | 2014 | 3,753 |
| 36 | Cancer Metastasis: Building a Framework | Cell | 2006 | 3,702 |
| 37 | Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors | Science | 2018 | 3,689 |
| 38 | Tumour exosome integrins determine organotropic metastasis | Nature | 2015 | 3,688 |
| 39 | Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies | Science Translational Medicine | 2014 | 3,665 |
| 40 | Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS | Science | 1984 | 3,645 |
| 41 | Restoring function in exhausted CD8 T cells during chronic viral infection | Nature | 2006 | 3,471 |
| 42 | Molecular chaperones in cellular protein folding | Nature | 1996 | 3,443 |
| 43 | Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation | Nature | 2013 | 3,412 |
| 44 | A microRNA polycistron as a potential human oncogene | Nature | 2005 | 3,390 |
| 45 | A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing | Cell | 2007 | 3,390 |
| 46 | Assessing the Performance of Prediction Models | Epidemiology | 2010 | 3,387 |
| 47 | TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells | Nature | 2018 | 3,359 |
| 48 | International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma | Lancet Oncology, The | 2014 | 3,343 |
| 49 | Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma | New England Journal of Medicine | 2018 | 3,334 |
| 50 | The landscape of somatic copy-number alteration across human cancers | Nature | 2010 | 3,331 |
