| # | Title | Journal | Year | Citations |
|---|
| 1 | Peginterferon Alfa-2a plus Ribavirin for Chronic Hepatitis C Virus Infection | New England Journal of Medicine | 2002 | 6,268 |
| 2 | International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS) | Journal of Thrombosis and Haemostasis | 2006 | 6,039 |
| 3 | 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure | European Heart Journal | 2021 | 5,558 |
| 4 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 5 | Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes | Trends in Immunology | 2002 | 4,494 |
| 6 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 7 | The ferritins: molecular properties, iron storage function and cellular regulation | Biochimica Et Biophysica Acta - Bioenergetics | 1996 | 2,273 |
| 8 | Hepatocellular carcinoma in cirrhosis: Incidence and risk factors | Gastroenterology | 2004 | 2,168 |
| 9 | Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer | New England Journal of Medicine | 2010 | 2,066 |
| 10 | Nomenclature of monocytes and dendritic cells in blood | Blood | 2010 | 2,046 |
| 11 | Autoantibodies against type I IFNs in patients with life-threatening COVID-19 | Science | 2020 | 1,983 |
| 12 | Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 | Science | 2020 | 1,749 |
| 13 | Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol Or Metoprolol European Trial (COMET): randomised controlled trial | Lancet, The | 2003 | 1,664 |
| 14 | The Global Health and Economic Burden of Hospitalizations for Heart Failure | Journal of the American College of Cardiology | 2014 | 1,640 |
| 15 | Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: ‘establishing normal and reference values’ | European Heart Journal | 2010 | 1,637 |
| 16 | Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon | Nature Medicine | 1999 | 1,560 |
| 17 | Activation-Induced Cytidine Deaminase (AID) Deficiency Causes the Autosomal Recessive Form of the Hyper-IgM Syndrome (HIGM2) | Cell | 2000 | 1,489 |
| 18 | Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19) | JAMA Cardiology | 2020 | 1,465 |
| 19 | Criteria for the diagnosis of corticobasal degeneration | Neurology | 2013 | 1,445 |
| 20 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 21 | A High-Order Accurate Discontinuous Finite Element Method for the Numerical Solution of the Compressible Navier–Stokes Equations | Journal of Computational Physics | 1997 | 1,422 |
| 22 | Industrial Internet of Things: Challenges, Opportunities, and Directions | IEEE Transactions on Industrial Informatics | 2018 | 1,418 |
| 23 | Stable and highly sensitive gas sensors based on semiconducting oxide nanobelts | Applied Physics Letters | 2002 | 1,400 |
| 24 | Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes | Nature Biotechnology | 2008 | 1,275 |
| 25 | 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus | Annals of the Rheumatic Diseases | 2019 | 1,265 |
| 26 | Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document | Journal of Hypertension | 2009 | 1,236 |
| 27 | Peginterferon Alfa-2a plus Ribavirin for Chronic Hepatitis C Virus Infection in HIV-Infected Patients | New England Journal of Medicine | 2004 | 1,220 |
| 28 | Central Role for G Protein-Coupled Phosphoinositide 3-Kinase in Inflammation | Science | 2000 | 1,187 |
| 29 | Diagnosis and Complications of Cushing’s Syndrome: A Consensus Statement | Journal of Clinical Endocrinology and Metabolism | 2003 | 1,184 |
| 30 | The COVID-19 social media infodemic | Scientific Reports | 2020 | 1,167 |
| 31 | Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis | Cytokine and Growth Factor Reviews | 2005 | 1,126 |
| 32 | A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity | Nature | 2009 | 1,114 |
| 33 | Critical illness polyneuropathy and myopathy: a major cause of muscle weakness and paralysis | Lancet Neurology, The | 2011 | 1,113 |
| 34 | Mitochondrial Biogenesis in Mammals: The Role of Endogenous Nitric Oxide | Science | 2003 | 1,110 |
| 35 | Natural history of chronic hepatitis B: Special emphasis on disease progression and prognostic factors | Journal of Hepatology | 2008 | 1,105 |
| 36 | Sotagliflozin in Patients with Diabetes and Recent Worsening Heart Failure | New England Journal of Medicine | 2021 | 1,080 |
| 37 | Cardiovascular pre-participation screening of young competitive athletes for prevention of sudden death: proposal for a common European protocol | European Heart Journal | 2005 | 1,037 |
| 38 | TREM-1 amplifies inflammation and is a crucial mediator of septic shock | Nature | 2001 | 1,013 |
| 39 | A technical guide to tDCS, and related non-invasive brain stimulation tools | Clinical Neurophysiology | 2016 | 998 |
| 40 | Pathophysiology of the Neuroregulation of Growth Hormone Secretion in Experimental Animals and the Human* | Endocrine Reviews | 1998 | 942 |
| 41 | Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature | 2022 | 929 |
| 42 | Glucocorticoid-induced osteoporosis: pathophysiology and therapy | Osteoporosis International | 2007 | 914 |
| 43 | 2016 European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents | Journal of Hypertension | 2016 | 898 |
| 44 | The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM | Nature | 1998 | 894 |
| 45 | Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly | Neurobiology of Aging | 2017 | 870 |
| 46 | Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID) | Nature | 1995 | 864 |
| 47 | Immunosuppressive therapy in lupus nephritis: The Euro-Lupus Nephritis Trial, a randomized trial of low-dose versus high-dose intravenous cyclophosphamide | Arthritis and Rheumatism | 2002 | 849 |
| 48 | The 2018 update of the WHO-EORTC classification for primary cutaneous lymphomas | Blood | 2019 | 846 |
| 49 | Criteria for Cure of Acromegaly: A Consensus Statement | Journal of Clinical Endocrinology and Metabolism | 2000 | 839 |
| 50 | RECEPTORS FOR HLA CLASS-I MOLECULES IN HUMAN NATURAL KILLER CELLS | Annual Review of Immunology | 1996 | 833 |
