| # | Title | Journal | Year | Citations |
|---|
| 1 | Qualitative content analysis in nursing research: concepts, procedures and measures to achieve trustworthiness | Nurse Education Today | 2004 | 13,080 |
| 2 | A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity | Science | 2012 | 12,811 |
| 3 | Involvement of the Superoxide Anion Radical in the Autoxidation of Pyrogallol and a Convenient Assay for Superoxide Dismutase | FEBS Journal | 1974 | 7,903 |
| 4 | PLS-regression: a basic tool of chemometrics | Chemometrics and Intelligent Laboratory Systems | 2001 | 7,224 |
| 5 | Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol | Lancet, The | 2002 | 4,917 |
| 6 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 7 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
| 8 | ILAE Official Report: A practical clinical definition of epilepsy | Epilepsia | 2014 | 3,770 |
| 9 | Imaging Cognition II: An Empirical Review of 275 PET and fMRI Studies | Journal of Cognitive Neuroscience | 2000 | 3,281 |
| 10 | Fragmentation and Flow Regulation of the World's Large River Systems | Science | 2005 | 2,811 |
| 11 | Discovery and refinement of loci associated with lipid levels | Nature Genetics | 2013 | 2,641 |
| 12 | EAU Guidelines on Renal Cell Carcinoma: 2014 Update | European Urology | 2015 | 2,445 |
| 13 | The reproductive number of COVID-19 is higher compared to SARS coronavirus | Journal of Travel Medicine | 2020 | 2,370 |
| 14 | A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial | Lancet, The | 2015 | 2,307 |
| 15 | Cross-Validatory Estimation of the Number of Components in Factor and Principal Components Models | Technometrics | 1978 | 2,161 |
| 16 | CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III | Nature | 2011 | 2,093 |
| 17 | Evolution and classification of the CRISPR–Cas systems | Nature Reviews Microbiology | 2011 | 2,078 |
| 18 | Bevacizumab plus Radiotherapy–Temozolomide for Newly Diagnosed Glioblastoma | New England Journal of Medicine | 2014 | 2,078 |
| 19 | Biodiversity redistribution under climate change: Impacts on ecosystems and human well-being | Science | 2017 | 2,026 |
| 20 | New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk | Nature Genetics | 2010 | 1,982 |
| 21 | Genetics of rheumatoid arthritis contributes to biology and drug discovery | Nature | 2014 | 1,974 |
| 22 | Orthogonal projections to latent structures (O-PLS) | Journal of Chemometrics | 2002 | 1,958 |
| 23 | Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis | New England Journal of Medicine | 2018 | 1,944 |
| 24 | Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension (STOP-Hypertension) | Lancet, The | 1991 | 1,829 |
| 25 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 26 | What is the cause of the ageing atrophy? | Journal of the Neurological Sciences | 1988 | 1,792 |
| 27 | Insulin-promoter-factor 1 is required for pancreas development in mice | Nature | 1994 | 1,712 |
| 28 | Methodological challenges in qualitative content analysis: A discussion paper | Nurse Education Today | 2017 | 1,694 |
| 29 | Inheritance of Alcohol Abuse | Archives of General Psychiatry | 1981 | 1,680 |
| 30 | Mortality risk attributable to high and low ambient temperature: a multicountry observational study | Lancet, The | 2015 | 1,676 |
| 31 | Global Patterns of Influenza A Virus in Wild Birds | Science | 2006 | 1,619 |
| 32 | Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis | Arthritis and Rheumatism | 2003 | 1,574 |
| 33 | High‐resolution mapping of the world's reservoirs and dams for sustainable river‐flow management | Frontiers in Ecology and the Environment | 2011 | 1,540 |
| 34 | European Prospective Investigation into Cancer and Nutrition (EPIC): study populations and data collection | Public Health Nutrition | 2002 | 1,539 |
| 35 | Incidence trends for childhood type 1 diabetes in Europe during 1989–2003 and predicted new cases 2005–20: a multicentre prospective registration study | Lancet, The | 2009 | 1,524 |
| 36 | Coding and use of tactile signals from the fingertips in object manipulation tasks | Nature Reviews Neuroscience | 2009 | 1,519 |
| 37 | Pretreatment of lignocellulose: Formation of inhibitory by-products and strategies for minimizing their effects | Bioresource Technology | 2016 | 1,507 |
| 38 | Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients | Progress in Nuclear Magnetic Resonance Spectroscopy | 1999 | 1,490 |
| 39 | Fragmentation and Flow Regulation of River Systems in the Northern Third of the World | Science | 1994 | 1,485 |
| 40 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 41 | Roles of glabrous skin receptors and sensorimotor memory in automatic control of precision grip when lifting rougher or more slippery objects | Experimental Brain Research | 1984 | 1,410 |
| 42 | The content and development of mobbing at work | European Journal of Work and Organizational Psychology | 1996 | 1,385 |
| 43 | Attack vulnerability of complex networks | Physical Review E | 2002 | 1,365 |
| 44 | A pigment-binding protein essential for regulation of photosynthetic light harvesting | Nature | 2000 | 1,354 |
| 45 | Factors affecting the long-term results of endodontic treatment | Journal of Endodontics | 1990 | 1,346 |
| 46 | Affective picture processing: An integrative review of ERP findings | Biological Psychology | 2008 | 1,334 |
| 47 | New genetic loci link adipose and insulin biology to body fat distribution | Nature | 2015 | 1,328 |
| 48 | The evolution of polyandry: multiple mating and female fitness in insects | Animal Behaviour | 2000 | 1,323 |
| 49 | Health and climate change: policy responses to protect public health | Lancet, The | 2015 | 1,311 |
| 50 | The Norway spruce genome sequence and conifer genome evolution | Nature | 2013 | 1,303 |
