| # | Title | Journal | Year | Citations |
|---|
| 1 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 9,397 |
| 2 | The worldwide leaf economics spectrum | Nature | 2004 | 6,489 |
| 3 | Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 6,376 |
| 4 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 5 | Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019 | Journal of the American College of Cardiology | 2020 | 4,468 |
| 6 | World Health Organization 2020 guidelines on physical activity and sedentary behaviour | British Journal of Sports Medicine | 2020 | 4,050 |
| 7 | Allergic Rhinitis and its Impact on Asthma (ARIA) 2008* | Allergy: European Journal of Allergy and Clinical Immunology | 2008 | 3,827 |
| 8 | Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis | Lancet Infectious Diseases, The | 2018 | 3,672 |
| 9 | Plastic Pollution in the World's Oceans: More than 5 Trillion Plastic Pieces Weighing over 250,000 Tons Afloat at Sea | PLoS ONE | 2014 | 3,144 |
| 10 | An Official American Thoracic Society/European Respiratory Society Statement: Update of the International Multidisciplinary Classification of the Idiopathic Interstitial Pneumonias | American Journal of Respiratory and Critical Care Medicine | 2013 | 3,134 |
| 11 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 12 | Trophic Downgrading of Planet Earth | Science | 2011 | 3,030 |
| 13 | International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma | European Respiratory Journal | 2014 | 2,898 |
| 14 | Naturalization and invasion of alien plants: concepts and definitions | Diversity and Distributions | 2000 | 2,724 |
| 15 | RDP4: Detection and analysis of recombination patterns in virus genomes | Virus Evolution | 2015 | 2,621 |
| 16 | Obesity and the risk of myocardial infarction in 27 000 participants from 52 countries: a case-control study | Lancet, The | 2005 | 2,414 |
| 17 | Paris Agreement climate proposals need a boost to keep warming well below 2 °C | Nature | 2016 | 2,397 |
| 18 | Fire in the Earth System | Science | 2009 | 2,330 |
| 19 | A DNA barcode for land plants | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 2,120 |
| 20 | Biodiversity redistribution under climate change: Impacts on ecosystems and human well-being | Science | 2017 | 2,026 |
| 21 | TRY – a global database of plant traits | Global Change Biology | 2011 | 2,002 |
| 22 | The epidemiology of obsessive-compulsive disorder in the National Comorbidity Survey Replication | Molecular Psychiatry | 2010 | 1,995 |
| 23 | Holocene climate variability | Quaternary Research | 2004 | 1,994 |
| 24 | Macrophage-specific PPARγ controls alternative activation and improves insulin resistance | Nature | 2007 | 1,804 |
| 25 | Fire as a global ‘herbivore’: the ecology and evolution of flammable ecosystems | Trends in Ecology and Evolution | 2005 | 1,750 |
| 26 | Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 1,708 |
| 27 | Declining oxygen in the global ocean and coastal waters | Science | 2018 | 1,707 |
| 28 | Grand challenges in global mental health | Nature | 2011 | 1,654 |
| 29 | The Global Syndemic of Obesity, Undernutrition, and Climate Change: The Lancet Commission report | Lancet, The | 2019 | 1,638 |
| 30 | An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis | Nature | 2010 | 1,632 |
| 31 | Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial | Lancet, The | 2019 | 1,625 |
| 32 | Ehlers-Danlos syndromes: Revised nosology, Villefranche, 1997 | American Journal of Medical Genetics Part A | 1998 | 1,624 |
| 33 | Challenges in the Quest for Keystones | BioScience | 1996 | 1,557 |
| 34 | Determinants of woody cover in African savannas | Nature | 2005 | 1,543 |
| 35 | RDP3: a flexible and fast computer program for analyzing recombination | Bioinformatics | 2010 | 1,524 |
| 36 | Worldwide access to treatment for end-stage kidney disease: a systematic review | Lancet, The | 2015 | 1,522 |
| 37 | The global distribution of ecosystems in a world without fire | New Phytologist | 2005 | 1,509 |
| 38 | Extending the Cross-Cultural Validity of the Theory of Basic Human Values with a Different Method of Measurement | Journal of Cross-Cultural Psychology | 2001 | 1,498 |
| 39 | THE STAR FORMATION EFFICIENCY IN NEARBY GALAXIES: MEASURING WHERE GAS FORMS STARS EFFECTIVELY | Astronomical Journal | 2008 | 1,481 |
| 40 | THE STAR FORMATION LAW IN NEARBY GALAXIES ON SUB-KPC SCALES | Astronomical Journal | 2008 | 1,409 |
| 41 | Detection of a SARS-CoV-2 variant of concern in South Africa | Nature | 2021 | 1,381 |
| 42 | RDP: detection of recombination amongst aligned sequences | Bioinformatics | 2000 | 1,369 |
| 43 | Defining trained immunity and its role in health and disease | Nature Reviews Immunology | 2020 | 1,345 |
| 44 | Functional landscape heterogeneity and animal biodiversity in agricultural landscapes | Ecology Letters | 2011 | 1,279 |
| 45 | A global perspective on environmental flow assessment: emerging trends in the development and application of environmental flow methodologies for rivers | River Research and Applications | 2003 | 1,250 |
| 46 | Global, regional, and national levels and causes of maternal mortality during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 | Lancet, The | 2014 | 1,230 |
| 47 | Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa | Nature | 2022 | 1,210 |
| 48 | SDT: A Virus Classification Tool Based on Pairwise Sequence Alignment and Identity Calculation | PLoS ONE | 2014 | 1,208 |
| 49 | The spectrum of latent tuberculosis: rethinking the biology and intervention strategies | Nature Reviews Microbiology | 2009 | 1,179 |
| 50 | Ecology of sprouting in woody plants: the persistence niche | Trends in Ecology and Evolution | 2001 | 1,168 |
