# | Title | Journal | Year | Citations |
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1 | AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading | Journal of Computational Chemistry | 2010 | 21,573 |
2 | AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility | Journal of Computational Chemistry | 2009 | 16,850 |
3 | Development and testing of a general amber force field | Journal of Computational Chemistry | 2004 | 14,342 |
4 | The 1982 revised criteria for the classification of systemic lupus erythematosus | Arthritis and Rheumatism | 1982 | 12,163 |
5 | Phosphorus Assay in Column Chromatography | Journal of Biological Chemistry | 1959 | 12,077 |
6 | Bioconductor: open software development for computational biology and bioinformatics | Genome Biology | 2004 | 10,796 |
7 | A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes | Angewandte Chemie - International Edition | 2002 | 10,242 |
8 | Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function | Journal of Computational Chemistry | 1998 | 8,897 |
9 | The Amber biomolecular simulation programs | Journal of Computational Chemistry | 2005 | 7,742 |
10 | Updating P300: An integrative theory of P3a and P3b | Clinical Neurophysiology | 2007 | 5,951 |
11 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
12 | Large-scale analysis of the yeast proteome by multidimensional protein identification technology | Nature Biotechnology | 2001 | 4,540 |
13 | Neurocircuitry of Addiction | Neuropsychopharmacology | 2010 | 4,187 |
14 | A second generation human haplotype map of over 3.1 million SNPs | Nature | 2007 | 4,137 |
15 | XCMS: Processing Mass Spectrometry Data for Metabolite Profiling Using Nonlinear Peak Alignment, Matching, and Identification | Analytical Chemistry | 2006 | 4,128 |
16 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 | Cell Death and Differentiation | 2018 | 4,036 |
17 | The proximal origin of SARS-CoV-2 | Nature Medicine | 2020 | 3,871 |
18 | Palladium(II)‐Catalyzed CH Activation/CC Cross‐Coupling Reactions: Versatility and Practicality | Angewandte Chemie - International Edition | 2009 | 3,842 |
19 | Synthesis of proteins by native chemical ligation | Science | 1994 | 3,712 |
20 | The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity | Proceedings of the National Academy of Sciences of the United States of America | 1998 | 3,579 |
21 | Intrinsically unstructured proteins and their functions | Nature Reviews Molecular Cell Biology | 2005 | 3,403 |
22 | Regulated portals of entry into the cell | Nature | 2003 | 3,355 |
23 | Interferon Alfa-2b Alone or in Combination with Ribavirin as Initial Treatment for Chronic Hepatitis C | New England Journal of Medicine | 1998 | 3,341 |
24 | Neurons Containing Hypocretin (Orexin) Project to Multiple Neuronal Systems | Journal of Neuroscience | 1998 | 3,182 |
25 | Extending the treatment of backbone energetics in protein force fields: Limitations of gas-phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics simulations | Journal of Computational Chemistry | 2004 | 3,145 |
26 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
27 | ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering | Trends in Biotechnology | 2013 | 3,116 |
28 | High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor | Science | 2007 | 3,112 |
29 | Requirement of vascular integrin alpha v beta 3 for angiogenesis | Science | 1994 | 2,964 |
30 | High-performance medicine: the convergence of human and artificial intelligence | Nature Medicine | 2019 | 2,938 |
31 | The growing impact of click chemistry on drug discovery | Drug Discovery Today | 2003 | 2,880 |
32 | AMBER, a package of computer programs for applying molecular mechanics, normal mode analysis, molecular dynamics and free energy calculations to simulate the structural and energetic properties of molecules | Computer Physics Communications | 1995 | 2,839 |
33 | Toll-like receptors in the induction of the innate immune response | Nature | 2000 | 2,784 |
34 | Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm | Journal of Molecular Biology | 1999 | 2,668 |
35 | A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells | Science | 1994 | 2,583 |
36 | Proline-Catalyzed Direct Asymmetric Aldol Reactions | Journal of the American Chemical Society | 2000 | 2,580 |
37 | Transcatheter Aortic-Valve Replacement with a Self-Expanding Valve in Low-Risk Patients | New England Journal of Medicine | 2019 | 2,530 |
38 | Weak Coordination as a Powerful Means for Developing Broadly Useful C–H Functionalization Reactions | Accounts of Chemical Research | 2012 | 2,513 |
39 | Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein | Nature | 1995 | 2,463 |
40 | Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance | Chemical Reviews | 2017 | 2,449 |
41 | Palladium-Catalyzed Cross-Coupling Reactions in Total Synthesis | Angewandte Chemie - International Edition | 2005 | 2,426 |
42 | Drug Addiction, Dysregulation of Reward, and Allostasis | Neuropsychopharmacology | 2001 | 2,425 |
43 | The Chlamydomonas Genome Reveals the Evolution of Key Animal and Plant Functions | Science | 2007 | 2,354 |
44 | Drug Abuse: Hedonic Homeostatic Dysregulation | Science | 1997 | 2,304 |
45 | A Model for Random Sampling and Estimation of Relative Protein Abundance in Shotgun Proteomics | Analytical Chemistry | 2004 | 2,280 |
46 | Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels | Cell | 1994 | 2,265 |
47 | 1H, 13C and 15N chemical shift referencing in biomolecular NMR | Journal of Biomolecular NMR | 1995 | 2,216 |
48 | Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment | Cell | 1993 | 2,215 |
49 | Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 2,198 |
50 | Focal adhesion kinase: in command and control of cell motility | Nature Reviews Molecular Cell Biology | 2005 | 2,193 |