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Top Articles

#TitleJournalYearCitations
1PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast CancerBreast Care201620,872
2Fast and sensitive protein alignment using DIAMONDNature Methods20158,761
3Down-Regulation of Na+/K+ATPase Activity by Human Parvovirus B19 Capsid Protein VP1Cellular Physiology and Biochemistry20137,499
4Application of Phylogenetic Networks in Evolutionary StudiesMolecular Biology and Evolution20067,402
5The PRIDE database and related tools and resources in 2019: improving support for quantification dataNucleic Acids Research20196,449
6Regulation of the Voltage Gated K+Channel Kv1.3by Recombinant Human Klotho ProteinKidney and Blood Pressure Research20145,235
7Surface plasmon resonance sensors: reviewSensors and Actuators B: Chemical19994,817
8Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Autophagy20164,701
9Neuroinflammation in Alzheimer's diseaseLancet Neurology, The20154,129
10Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018Cell Death and Differentiation20184,036
11Nuclear ribosomal internal transcribed spacer (ITS) region as a universal DNA barcode marker for FungiProceedings of the National Academy of Sciences of the United States of America20124,012
12An equation for continuous chaosPhysics Letters, Section A: General, Atomic and Solid State Physics19763,241
13Review of Particle PhysicsProgress of Theoretical and Experimental Physics20203,177
14Image Style Transfer Using Convolutional Neural NetworksProgress of Theoretical and Experimental Physics20163,141
15Guidelines for the use and interpretation of assays for monitoring autophagyAutophagy20123,122
16Towards a unified paradigm for sequence‐based identification of fungiMolecular Ecology20132,997
17MEGAN analysis of metagenomic dataGenome Research20072,764
18A Renaissance of Elicitors: Perception of Microbe-Associated Molecular Patterns and Danger Signals by Pattern-Recognition ReceptorsAnnual Review of Plant Biology20092,714
19DeepLabCut: markerless pose estimation of user-defined body parts with deep learningNature Neuroscience20182,710
20Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic PathologyNeuron20042,653
21Stereospecific Olefin Polymerization with Chiral Metallocene CatalystsAngewandte Chemie International Edition in English19952,623
22antiSMASH 5.0: updates to the secondary metabolite genome mining pipelineNucleic Acids Research20192,410
23PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1Nature Cell Biology20102,360
24Local, Efflux-Dependent Auxin Gradients as a Common Module for Plant Organ FormationCell20032,313
25Conduction Model of Metal Oxide Gas SensorsCell20012,216
26Genome-wide association study identifies novel breast cancer susceptibility lociNature20072,165
27SYFPEITHI: database for MHC ligands and peptide motifsImmunogenetics19992,156
28Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): Standardized protocol and reference valuesPain20061,939
29Combined Vemurafenib and Cobimetinib in BRAF-Mutated MelanomaNew England Journal of Medicine20141,824
30The PIN auxin efflux facilitator network controls growth and patterning in Arabidopsis rootsNature20051,789
31antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clustersNucleic Acids Research20151,764
32Genome-wide association study reveals genetic risk underlying Parkinson's diseaseNature Genetics20091,745
33RAGE Mediates a Novel Proinflammatory AxisCell19991,727
34Functional Significance of Cell Volume Regulatory MechanismsPhysiological Reviews19981,706
35Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's diseaseNature Genetics20141,685
36Review of Particle PhysicsProgress of Theoretical and Experimental Physics20221,679
37Efflux-dependent auxin gradients establish the apical–basal axis of ArabidopsisNature20031,672
38Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formationNature19951,666
39Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputationNature19951,659
40Nanosilver: A nanoproduct in medical applicationToxicology Letters20081,624
41A flagellin-induced complex of the receptor FLS2 and BAK1 initiates plant defenceNature20071,619
42Micro-algae as a source of proteinBiotechnology Advances20071,586
43Scale for the assessment and rating of ataxia: Development of a new clinical scaleNeurology20061,579
44A complex secretory program orchestrated by the inflammasome controls paracrine senescenceNature Cell Biology20131,566
45Feature-based attention influences motion processing gain in macaque visual cortexNature19991,563
46Banach Lattices and Positive OperatorsNature19741,530
47Electronic Nose:  Current Status and Future TrendsChemical Reviews20081,529
48Pharmacology ofCurcuma longaPlanta Medica19911,526
49Transmission and spreading of tauopathy in transgenic mouse brainNature Cell Biology20091,515
50Visualization of protein interactions in living plant cells using bimolecular fluorescence complementationPlant Journal20041,514