# | Title | Journal | Year | Citations |
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1 | T-cell activation by transitory neo-antigens derived from distinct microbial pathways | Nature | 2014 | 731 |
2 | Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells | Journal of Experimental Medicine | 2013 | 516 |
3 | Natural product and natural product derived drugs in clinical trials | Natural Product Reports | 2014 | 471 |
4 | Antibiotics in the clinical pipeline in 2013 | Journal of Antibiotics | 2013 | 348 |
5 | Constraining Cyclic Peptides To Mimic Protein Structure Motifs | Angewandte Chemie - International Edition | 2014 | 338 |
6 | Role for NLRP3 Inflammasome–mediated, IL-1β–Dependent Responses in Severe, Steroid-Resistant Asthma | American Journal of Respiratory and Critical Care Medicine | 2017 | 304 |
7 | Structural and Functional Analysis of a Plant Resistance Protein TIR Domain Reveals Interfaces for Self-Association, Signaling, and Autoregulation | Cell Host and Microbe | 2011 | 301 |
8 | ConoServer: updated content, knowledge, and discovery tools in the conopeptide database | Nucleic Acids Research | 2012 | 298 |
9 | Alpha-synuclein structure and Parkinson’s disease – lessons and emerging principles | Molecular Neurodegeneration | 2019 | 262 |
10 | Recognition of vitamin B metabolites by mucosal-associated invariant T cells | Nature Communications | 2013 | 261 |
11 | A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells | Journal of Experimental Medicine | 2014 | 245 |
12 | Antibiotics in the clinical pipeline in 2011 | Journal of Antibiotics | 2011 | 236 |
13 | Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals | Mucosal Immunology | 2017 | 216 |
14 | Conopeptide characterization and classifications: An analysis using ConoServer | Toxicon | 2010 | 198 |
15 | Taking the Myc out of cancer: toward therapeutic strategies to directly inhibit c-Myc | Molecular Cancer | 2021 | 191 |
16 | Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase | Nature Communications | 2015 | 186 |
17 | MAIT cells protect against pulmonary Legionella longbeachae infection | Nature Communications | 2018 | 177 |
18 | Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension | Cardiovascular Research | 2019 | 165 |
19 | Discovery of a selective Na V 1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 164 |
20 | Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 162 |
21 | Comparative α‐Helicity of Cyclic Pentapeptides in Water | Angewandte Chemie - International Edition | 2014 | 153 |
22 | Complement C5a Receptor Facilitates Cancer Metastasis by Altering T-Cell Responses in the Metastatic Niche | Cancer Research | 2014 | 151 |
23 | Systemic delivery of peptides by the oral route: Formulation and medicinal chemistry approaches | Advanced Drug Delivery Reviews | 2020 | 150 |
24 | Targeting virulence not viability in the search for future antibacterials | British Journal of Clinical Pharmacology | 2015 | 144 |
25 | Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt‐induced hypertension in mice | British Journal of Pharmacology | 2016 | 143 |
26 | Bioactive cystine knot proteins | Current Opinion in Chemical Biology | 2011 | 142 |
27 | Recent advances in microtubule-stabilizing agents | European Journal of Medicinal Chemistry | 2018 | 133 |
28 | The intracellular pathway for the presentation of vitamin B–related antigens by the antigen-presenting molecule MR1 | Nature Immunology | 2016 | 127 |
29 | Inflammasomes in the lung | Molecular Immunology | 2017 | 126 |
30 | Solving the α-Conotoxin Folding Problem: Efficient Selenium-Directed On-Resin Generation of More Potent and Stable Nicotinic Acetylcholine Receptor Antagonists | Journal of the American Chemical Society | 2010 | 124 |
31 | Improving on Nature: Making a Cyclic Heptapeptide Orally Bioavailable | Angewandte Chemie - International Edition | 2014 | 123 |
32 | Recognition of Vitamin B Precursors and Byproducts by Mucosal Associated Invariant T Cells | Journal of Biological Chemistry | 2015 | 123 |
33 | Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites | Journal of Immunology | 2015 | 121 |
34 | Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells | Nature Communications | 2017 | 113 |
35 | Inflammasomes in COPD and neutrophilic asthma | Thorax | 2015 | 109 |
36 | Catalyst‐Free N‐Arylation Using Unactivated Fluorobenzenes | Angewandte Chemie - International Edition | 2012 | 105 |
37 | Possible roles for Munc18-1 domain 3a and Syntaxin1 N-peptide and C-terminal anchor in SNARE complex formation | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 101 |
38 | MAIT Cells Promote Tumor Initiation, Growth, and Metastases via Tumor MR1 | Cancer Discovery | 2020 | 101 |
39 | Clawing through Evolution: Toxin Diversification and Convergence in the Ancient Lineage Chilopoda (Centipedes) | Molecular Biology and Evolution | 2014 | 100 |
40 | Therapeutic Potential of Cone Snail Venom Peptides (Conopeptides) | Current Topics in Medicinal Chemistry | 2012 | 96 |
41 | Novel Agonists and Antagonists for Human Protease Activated Receptor 2 | Journal of Medicinal Chemistry | 2010 | 91 |
42 | Invited reviewnative chemical ligation applied to the synthesis and bioengineering of circular peptides and proteins | Biopolymers | 2010 | 90 |
43 | Staurosporines Disrupt Phosphatidylserine Trafficking and Mislocalize Ras Proteins | Journal of Biological Chemistry | 2012 | 89 |
44 | Optimized deep-targeted proteotranscriptomic profiling reveals unexplored Conus toxin diversity and novel cysteine frameworks | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 85 |
45 | Determination of the α-Conotoxin Vc1.1 Binding Site on the α9α10 Nicotinic Acetylcholine Receptor | Journal of Medicinal Chemistry | 2013 | 84 |
46 | Circular proteins and mechanisms of cyclization | Biopolymers | 2010 | 79 |
47 | Blockade of Neuronal α7-nAChR by α-Conotoxin ImI Explained by Computational Scanning and Energy Calculations | PLoS Computational Biology | 2011 | 77 |
48 | α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABABreceptors | Gut | 2017 | 77 |
49 | Extracting value: mechanistic insights into the formation of natural product artifacts – case studies in marine natural products | Natural Product Reports | 2020 | 76 |
50 | IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection | Science Immunology | 2019 | 75 |