| # | Title | Journal | Year | Citations |
|---|
| 1 | CheckM: assessing the quality of microbial genomes recovered from isolates, single cells, and metagenomes | Genome Research | 2015 | 7,539 |
| 2 | Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors | Nature | 2020 | 3,133 |
| 3 | Easyfig: a genome comparison visualizer | Bioinformatics | 2011 | 2,861 |
| 4 | BLAST Ring Image Generator (BRIG): simple prokaryote genome comparisons | BMC Genomics | 2011 | 2,691 |
| 5 | A standardized bacterial taxonomy based on genome phylogeny substantially revises the tree of life | Nature Biotechnology | 2018 | 2,615 |
| 6 | GTDB-Tk: a toolkit to classify genomes with the Genome Taxonomy Database | Bioinformatics | 2020 | 2,524 |
| 7 | Definition and testing of the GROMOS force-field versions 54A7 and 54B7 | European Biophysics Journal | 2011 | 1,902 |
| 8 | Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea | Nature Biotechnology | 2017 | 1,512 |
| 9 | Recovery of nearly 8,000 metagenome-assembled genomes substantially expands the tree of life | Nature Microbiology | 2017 | 1,465 |
| 10 | Fabrication of Graphene/Polyaniline Composite Paper via In Situ Anodic Electropolymerization for High-Performance Flexible Electrode | ACS Nano | 2009 | 1,464 |
| 11 | An Automated Force Field Topology Builder (ATB) and Repository: Version 1.0 | Journal of Chemical Theory and Computation | 2011 | 1,425 |
| 12 | First confirmed detection of SARS-CoV-2 in untreated wastewater in Australia: A proof of concept for the wastewater surveillance of COVID-19 in the community | Science of the Total Environment | 2020 | 1,393 |
| 13 | Structure of the RNA-dependent RNA polymerase from COVID-19 virus | Science | 2020 | 1,228 |
| 14 | Genome sequences of rare, uncultured bacteria obtained by differential coverage binning of multiple metagenomes | Nature Biotechnology | 2013 | 1,176 |
| 15 | Anaerobic oxidation of methane coupled to nitrate reduction in a novel archaeal lineage | Nature | 2013 | 1,029 |
| 16 | Emerging pathogenic links between microbiota and the gut–lung axis | Nature Reviews Microbiology | 2017 | 950 |
| 17 | Heterogeneous nanocarbon materials for oxygen reduction reaction | Energy and Environmental Science | 2014 | 922 |
| 18 | Antimicrobial Resistance in ESKAPE Pathogens | Clinical Microbiology Reviews | 2020 | 898 |
| 19 | A complete domain-to-species taxonomy for Bacteria and Archaea | Nature Biotechnology | 2020 | 883 |
| 20 | Proposal to reclassify the proteobacterial classes Deltaproteobacteria and Oligoflexia, and the phylum Thermodesulfobacteria into four phyla reflecting major functional capabilities | International Journal of Systematic and Evolutionary Microbiology | 2020 | 830 |
| 21 | Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation | Nature Nanotechnology | 2011 | 781 |
| 22 | Carbon–sulfur composites for Li–S batteries: status and prospects | Journal of Materials Chemistry A | 2013 | 757 |
| 23 | Fibrous Hybrid of Graphene and Sulfur Nanocrystals for High-Performance Lithium–Sulfur Batteries | ACS Nano | 2013 | 722 |
| 24 | Methane metabolism in the archaeal phylum Bathyarchaeota revealed by genome-centric metagenomics | Science | 2015 | 677 |
| 25 | Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase | Cell | 2020 | 672 |
| 26 | GTDB: an ongoing census of bacterial and archaeal diversity through a phylogenetically consistent, rank normalized and complete genome-based taxonomy | Nucleic Acids Research | 2022 | 662 |
| 27 | Clay nanosheets for topical delivery of RNAi for sustained protection against plant viruses | Nature Plants | 2017 | 641 |
| 28 | A unified catalog of 204,938 reference genomes from the human gut microbiome | Nature Biotechnology | 2021 | 628 |
| 29 | Minimum information about a marker gene sequence (MIMARKS) and minimum information about any (x) sequence (MIxS) specifications | Nature Biotechnology | 2011 | 608 |
| 30 | American Gut: an Open Platform for Citizen Science Microbiome Research | MSystems | 2018 | 604 |
| 31 | MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition | Nature Chemical Biology | 2019 | 561 |
| 32 | Effect of Piperacillin-Tazobactam vs Meropenem on 30-Day Mortality for Patients With E coli or Klebsiella pneumoniae Bloodstream Infection and Ceftriaxone Resistance | JAMA - Journal of the American Medical Association | 2018 | 538 |
| 33 | Impact of training sets on classification of high-throughput bacterial 16s rRNA gene surveys | ISME Journal | 2012 | 537 |
| 34 | Genomic characterization of the uncultured Bacteroidales family S24-7 inhabiting the guts of homeothermic animals | Microbiome | 2016 | 533 |
| 35 | The Human Immune Response to Dengue Virus Is Dominated by Highly Cross-Reactive Antibodies Endowed with Neutralizing and Enhancing Activity | Cell Host and Microbe | 2010 | 526 |
| 36 | Global dissemination of a multidrug resistant Escherichia coli clone | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 498 |
| 37 | Emerging evidence for functional peptides encoded by short open reading frames | Nature Reviews Genetics | 2014 | 496 |
| 38 | Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer | Nature Genetics | 2013 | 493 |
| 39 | Genome sequences of the human body louse and its primary endosymbiont provide insights into the permanent parasitic lifestyle | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 482 |
| 40 | Coordination of Atomic Co–Pt Coupling Species at Carbon Defects as Active Sites for Oxygen Reduction Reaction | Journal of the American Chemical Society | 2018 | 464 |
| 41 | Methylotrophic methanogenesis discovered in the archaeal phylum Verstraetearchaeota | Nature Microbiology | 2016 | 459 |
| 42 | Peptide-based synthetic vaccines | Chemical Science | 2016 | 450 |
| 43 | Functional diversity of the hnRNPs: past, present and perspectives | Biochemical Journal | 2010 | 439 |
| 44 | The flavivirus NS1 protein: Molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker | Antiviral Research | 2013 | 425 |
| 45 | Testing and validation of the Automated Topology Builder (ATB) version 2.0: prediction of hydration free enthalpies | Journal of Computer-Aided Molecular Design | 2014 | 416 |
| 46 | Minimum Information about an Uncultivated Virus Genome (MIUViG) | Nature Biotechnology | 2019 | 414 |
| 47 | Beyond the bacterium: planctomycetes challenge our concepts of microbial structure and function | Nature Reviews Microbiology | 2011 | 410 |
| 48 | Comparative Genomic Analysis of the Class Epsilonproteobacteria and Proposed Reclassification to Epsilonbacteraeota (phyl. nov.) | Frontiers in Microbiology | 2017 | 409 |
| 49 | AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC | Cell Death and Differentiation | 2013 | 402 |
| 50 | Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity | Journal of Experimental Medicine | 2018 | 396 |
