| Regulation of PD-L1: a novel role of pro-survival signalling in cancer | Annals of Oncology | 2016 | 429 |
| Global economic burden of schizophrenia: a systematic review | Neuropsychiatric Disease and Treatment | 2016 | 249 |
| The importance of amylose and amylopectin fine structure for textural properties of cooked rice grains | Food Chemistry | 2016 | 234 |
| Continuous versus Intermittent β-Lactam Infusion in Severe Sepsis. A Meta-analysis of Individual Patient Data from Randomized Trials | American Journal of Respiratory and Critical Care Medicine | 2016 | 192 |
| Bioerodable PLGA-Based Microparticles for Producing Sustained-Release Drug Formulations and Strategies for Improving Drug Loading | Frontiers in Pharmacology | 2016 | 179 |
| Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis | Intensive Care Medicine | 2016 | 172 |
| Prospective Associations between Depression and Obesity for Adolescent Males and Females- A Systematic Review and Meta-Analysis of Longitudinal Studies | PLoS ONE | 2016 | 171 |
| Skin models for the testing of transdermal drugs | Clinical Pharmacology: Advances and Applications | 2016 | 131 |
| Is there a bi-directional relationship between depression and obesity among adult men and women? Systematic review and bias-adjusted meta analysis | Asian Journal of Psychiatry | 2016 | 105 |
| Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort | Journal of Antimicrobial Chemotherapy | 2016 | 104 |
| The necessity-concerns framework predicts adherence to medication in multiple illness conditions: A meta-analysis | Patient Education and Counseling | 2016 | 96 |
| Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) | World Journal of Emergency Surgery | 2016 | 95 |
| Clinical and economic impact of non-adherence to antidepressants in major depressive disorder: A systematic review | Journal of Affective Disorders | 2016 | 91 |
| Single-cell lineage tracing in the mammary gland reveals stochastic clonal dispersion of stem/progenitor cell progeny | Nature Communications | 2016 | 88 |
| Discovery and Structure-Activity Relationships of a Highly Selective Butyrylcholinesterase Inhibitor by Structure-Based Virtual Screening | Journal of Medicinal Chemistry | 2016 | 84 |
| Therapeutic drug monitoring of anti-infective agents in critically ill patients | Expert Review of Clinical Pharmacology | 2016 | 77 |
| Metal chelation, radical scavenging and inhibition of Aβ₄₂ fibrillation by food constituents in relation to Alzheimer's disease | Food Chemistry | 2016 | 76 |
| Enhancing delivery and cytotoxicity of resveratrol through a dual nanoencapsulation approach | Journal of Colloid and Interface Science | 2016 | 75 |
| Analgesic Effects of GpTx-1, PF-04856264 and CNV1014802 in a Mouse Model of NaV1.7-Mediated Pain | Toxins | 2016 | 75 |
| Cost-effectiveness of Store-and-Forward Teledermatology: A Systematic Review | JAMA Dermatology | 2016 | 75 |
| Short- and Long-Term Tracking of Anionic Ultrasmall Nanoparticles in Kidney | ACS Nano | 2016 | 72 |
| The effect of a patient centred care bundle intervention on pressure ulcer incidence (INTACT): A cluster randomised trial | International Journal of Nursing Studies | 2016 | 64 |
| Effect of obesity on the pharmacokinetics of antimicrobials in critically ill patients: A structured review | International Journal of Antimicrobial Agents | 2016 | 63 |
| Angiotensin- I- converting enzyme (ACE) inhibitory peptides from Pacific cod skin gelatin using ultrafiltration membranes | Process Biochemistry | 2016 | 63 |
| Altered purinergic receptor-Ca²⁺ signaling associated with hypoxia-induced epithelial-mesenchymal transition in breast cancer cells | Molecular Oncology | 2016 | 61 |
