Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1 | Cell | 2011 | 922 |
Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer--shifting the paradigm | Human Pathology | 2011 | 767 |
Recent progress in the diagnosis and treatment of ovarian cancer | Ca-A Cancer Journal for Clinicians | 2011 | 502 |
Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands | Cancer Cell | 2011 | 389 |
Hypoxia-inducible factor 1: regulator of mitochondrial metabolism and mediator of ischemic preconditioning | Biochimica Et Biophysica Acta - Molecular Cell Research | 2011 | 310 |
Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 307 |
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 296 |
Regulation of metabolism by hypoxia-inducible factor 1 | Cold Spring Harbor Symposia on Quantitative Biology | 2011 | 229 |
Small animal radiotherapy research platforms | Physics in Medicine and Biology | 2011 | 183 |
A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities | Prostate | 2011 | 159 |
Hypoxia-inducible factor 1 mediates increased expression of NADPH oxidase-2 in response to intermittent hypoxia | Journal of Cellular Physiology | 2011 | 148 |
Pyruvate kinase M2 regulates glucose metabolism by functioning as a coactivator for hypoxia-inducible factor 1 in cancer cells | Oncotarget | 2011 | 139 |
Regulation of glioblastoma stem cells by retinoic acid: role for Notch pathway inhibition | Oncogene | 2011 | 137 |
Subnormal cytokine profile in the tear fluid of keratoconus patients | PLoS ONE | 2011 | 130 |
Conserved herpesvirus kinases target the DNA damage response pathway and TIP60 histone acetyltransferase to promote virus replication | Cell Host and Microbe | 2011 | 126 |
Diagnosis of serous tubal intraepithelial carcinoma based on morphologic and immunohistochemical features: a reproducibility study | American Journal of Surgical Pathology | 2011 | 116 |
Transcriptome-wide binding sites for components of the Saccharomyces cerevisiae non-poly(A) termination pathway: Nrd1, Nab3, and Sen1 | PLoS Genetics | 2011 | 116 |
Yes-associated protein 1 is widely expressed in human brain tumors and promotes glioblastoma growth | Journal of Neuropathology and Experimental Neurology | 2011 | 110 |
Blockade of B7-H1 (programmed death ligand 1) enhances humoral immunity by positively regulating the generation of T follicular helper cells | Journal of Immunology | 2011 | 108 |
Ribosomal protein gene deletions in Diamond-Blackfan anemia | Blood | 2011 | 101 |
Signaling diversity of PKA achieved via a Ca2+-cAMP-PKA oscillatory circuit | Nature Chemical Biology | 2011 | 99 |
B-cell stimulatory cytokines and markers of immune activation are elevated several years prior to the diagnosis of systemic AIDS-associated non-Hodgkin B-cell lymphoma | Cancer Epidemiology Biomarkers and Prevention | 2011 | 98 |
Proteasome inhibitors induce nucleolar aggregation of proteasome target proteins and polyadenylated RNA by altering ubiquitin availability | Oncogene | 2011 | 97 |
MicroRNA-192 and -215 are upregulated in human gastric cancer in vivo and suppress ALCAM expression in vitro | Oncogene | 2011 | 96 |
Challenges in immunotherapy presented by the glioblastoma multiforme microenvironment | Clinical and Developmental Immunology | 2011 | 93 |