| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Factors Associated With Death in Critically Ill Patients With Coronavirus Disease 2019 in the US | JAMA Internal Medicine | 2020 | 754 |
| 2 | The Molecular Basis of Focal Cyst Formation in Human Autosomal Dominant Polycystic Kidney Disease Type I | Cell | 1996 | 564 |
| 3 | Tonicity-responsive enhancer binding protein, a Rel-like protein that stimulates transcription in response to hypertonicity | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 535 |
| 4 | Consensus guidelines for the diagnosis and clinical management of Erdheim-Chester disease | Blood | 2014 | 484 |
| 5 | Association Between Early Treatment With Tocilizumab and Mortality Among Critically Ill Patients With COVID-19 | JAMA Internal Medicine | 2021 | 404 |
| 6 | Transforming Growth Factor-β1 Induces an Epithelial-to-Mesenchymal Transition State in Mouse Hepatocytes in Vitro | Journal of Biological Chemistry | 2007 | 320 |
| 7 | Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 292 |
| 8 | Independent risk factors and natural history of renal dysfunction in liver transplant recipients | Liver Transplantation | 2003 | 250 |
| 9 | DASH (Dietary Approaches to Stop Hypertension) Diet and Risk of Subsequent Kidney Disease | American Journal of Kidney Diseases | 2016 | 234 |
| 10 | AKI Treated with Renal Replacement Therapy in Critically Ill Patients with COVID-19 | Journal of the American Society of Nephrology: JASN | 2021 | 223 |
| 11 | Association of Race and Ethnicity With Live Donor Kidney Transplantation in the United States From 1995 to 2014 | JAMA - Journal of the American Medical Association | 2018 | 219 |
| 12 | Polycystin:In vitrosynthesis,in vivotissue expression, and subcellular localization identifies a large membrane-associated protein | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 195 |
| 13 | Somatic Mutation in Individual Liver Cysts Supports a Two-Hit Model of Cystogenesis in Autosomal Dominant Polycystic Kidney Disease | Molecular Cell | 1998 | 195 |
| 14 | Biomarkers of Acute and Chronic Kidney Disease | Annual Review of Physiology | 2019 | 188 |
| 15 | Blood Pressure Excursions Below the Cerebral Autoregulation Threshold During Cardiac Surgery are Associated With Acute Kidney Injury* | Critical Care Medicine | 2013 | 186 |
| 16 | Regulation of Endothelial Nitric-oxide Synthase during Hypoxia | Journal of Biological Chemistry | 1996 | 176 |
| 17 | Dietary Protein Sources and Risk for Incident Chronic Kidney Disease: Results From the Atherosclerosis Risk in Communities (ARIC) Study | | 2017 | 176 |
| 18 | Transcription of the Sodium/myo-Inositol Cotransporter Gene Is Regulated by Multiple Tonicity-responsive Enhancers Spread over 50 Kilobase Pairs in the 5′-Flanking Region | Journal of Biological Chemistry | 1998 | 157 |
| 19 | A Flagellar Polycystin-2 Homolog Required for Male Fertility in Drosophila | Current Biology | 2003 | 147 |
| 20 | Effectiveness of Educational and Social Worker Interventions to Activate Patients' Discussion and Pursuit of Preemptive Living Donor Kidney Transplantation: A Randomized Controlled Trial | American Journal of Kidney Diseases | 2013 | 146 |
| 21 | An atlas of healthy and injured cell states and niches in the human kidney | Nature | 2023 | 144 |
| 22 | Polycystin-1 regulates STAT activity by a dual mechanism | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 125 |
| 23 | Hypertonicity-induced phosphorylation and nuclear localization of the transcription factor TonEBP | American Journal of Physiology - Cell Physiology | 2001 | 120 |
| 24 | WNK4 kinase regulates surface expression of the human sodium chloride cotransporter in mammalian cells | Kidney International | 2006 | 119 |
| 25 | TonEBP transcriptional activator in the cellular response to increased osmolality | Pflugers Archiv European Journal of Physiology | 2002 | 117 |
| 26 | Cis- andtrans-acting factors regulating transcription of the BGT1 gene in response to hypertonicity | American Journal of Physiology - Renal Physiology | 1998 | 105 |
| 27 | Post–Acute Kidney Injury Proteinuria and Subsequent Kidney Disease Progression | JAMA Internal Medicine | 2020 | 104 |
| 28 | Association between prediabetes and risk of chronic kidney disease: a systematic review and meta‐analysis | Diabetic Medicine | 2016 | 100 |
| 29 | Association of Multiple Plasma Biomarker Concentrations with Progression of Prevalent Diabetic Kidney Disease: Findings from the Chronic Renal Insufficiency Cohort (CRIC) Study | Journal of the American Society of Nephrology: JASN | 2021 | 91 |
| 30 | Characterization of cis-Autoproteolysis of Polycystin-1, the Product of Human Polycystic Kidney Disease 1 Gene | Journal of Biological Chemistry | 2007 | 90 |
| 31 | Gene conversion is a likely cause of mutation in PKD1 | Human Molecular Genetics | 1998 | 89 |
| 32 | HIV Type 1 RNA Level as a Clinical Indicator of Renal Pathology in HIV‐Infected Patients | Clinical Infectious Diseases | 2006 | 85 |
| 33 | A prospective cohort study of acute kidney injury and kidney outcomes, cardiovascular events, and death | Kidney International | 2021 | 85 |
| 34 | Use of Intravenous Iodinated Contrast Media in Patients With Kidney Disease | Kidney Medicine | 2020 | 78 |
| 35 | Sound Science before Quick Judgement Regarding RAS Blockade in COVID-19 | Clinical Journal of the American Society of Nephrology: CJASN | 2020 | 76 |
| 36 | Eculizumab cessation in atypical hemolytic uremic syndrome | Blood | 2017 | 73 |
| 37 | Reproducibility and Variability of Protein Analytes Measured Using a Multiplexed Modified Aptamer Assay | journal of applied laboratory medicine, The | 2019 | 68 |
| 38 | Long COVID and kidney disease | Nature Reviews Nephrology | 2021 | 68 |
| 39 | Association of Kidney Disease Measures With Ischemic Versus Hemorrhagic Strokes | Stroke | 2014 | 67 |
| 40 | Obesity, Hypertension, and Dyslipidemia in Childhood Are Key Modifiable Antecedents of Adult Cardiovascular Disease | Circulation | 2018 | 67 |
| 41 | Effects of phosphorylation of P-glycoprotein on multidrug resistance | Journal of Bioenergetics and Biomembranes | 1995 | 65 |
| 42 | Establishing core outcome domains in pediatric kidney disease: report of the Standardized Outcomes in Nephrology—Children and Adolescents (SONG-KIDS) consensus workshops | Kidney International | 2020 | 65 |
| 43 | Identification of a Polycystin-1 Cleavage Product, P100, That Regulates Store Operated Ca2+ Entry through Interactions with STIM1 | PLoS ONE | 2010 | 65 |
| 44 | Aortic abnormalities in males with Alport syndrome | Nephrology Dialysis Transplantation | 2010 | 62 |
| 45 | Evidence For and Against Direct Kidney Infection by SARS-CoV-2 in Patients with COVID-19 | Clinical Journal of the American Society of Nephrology: CJASN | 2021 | 61 |
| 46 | Kidney Function, Polypharmacy, and Potentially Inappropriate Medication Use in a Community-Based Cohort of Older Adults | Drugs and Aging | 2018 | 60 |
| 47 | Comorbidities in Chronic Pediatric Peritoneal Dialysis Patients: A Report of the International Pediatric Peritoneal Dialysis Network | Peritoneal Dialysis International | 2012 | 59 |
| 48 | Plasma galectin-3 levels are associated with the risk of incident chronic kidney disease | Kidney International | 2018 | 59 |
| 49 | Contrast-Associated Acute Kidney Injury and Serious Adverse Outcomes Following Angiography | Journal of the American College of Cardiology | 2020 | 59 |
| 50 | Transcriptional regulation by changes in tonicity | Kidney International | 2001 | 56 |
