| # | Title | Journal | Year | Citations |
|---|
| 1 | Cell Survival Responses to Environmental Stresses Via the Keap1-Nrf2-ARE Pathway | Annual Review of Pharmacology and Toxicology | 2007 | 3,054 |
| 2 | Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function | Trends in Pharmacological Sciences | 2006 | 1,237 |
| 3 | IMMUNOLOGIC BASIS OF ANTIGEN-INDUCED AIRWAY HYPERRESPONSIVENESS | Annual Review of Immunology | 1999 | 993 |
| 4 | Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray | Cancer Research | 2002 | 947 |
| 5 | Dysfunctional KEAP1–NRF2 Interaction in Non-Small-Cell Lung Cancer | PLoS Medicine | 2006 | 894 |
| 6 | Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis | Journal of Clinical Investigation | 2006 | 874 |
| 7 | Multiple-laboratory comparison of microarray platforms | Nature Methods | 2005 | 814 |
| 8 | Lead Exposure and Cardiovascular Disease—A Systematic Review | Environmental Health Perspectives | 2007 | 775 |
| 9 | Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria | Science | 2018 | 733 |
| 10 | The built environment and obesity: A systematic review of the epidemiologic evidence | Health and Place | 2010 | 678 |
| 11 | Respiratory risks from household air pollution in low and middle income countries | Lancet Respiratory Medicine,the | 2014 | 670 |
| 12 | Cumulative Childhood Stress and Autoimmune Diseases in Adults | Psychosomatic Medicine | 2009 | 616 |
| 13 | Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells | Nature | 2011 | 581 |
| 14 | Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction | Nature Medicine | 2010 | 549 |
| 15 | Co-Occurrence of Triclocarban and Triclosan in U.S. Water Resources | Environmental Science & Technology | 2005 | 544 |
| 16 | Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke–induced emphysema in mice | Journal of Clinical Investigation | 2004 | 535 |
| 17 | Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice | Journal of Experimental Medicine | 2005 | 529 |
| 18 | Enhanced Expression of the Transcription Factor Nrf2 by Cancer Chemopreventive Agents: Role of Antioxidant Response Element-Like Sequences in the nrf2 Promoter | Molecular and Cellular Biology | 2002 | 527 |
| 19 | Cord Serum Concentrations of Perfluorooctane Sulfonate (PFOS) and Perfluorooctanoate (PFOA) in Relation to Weight and Size at Birth | Environmental Health Perspectives | 2007 | 519 |
| 20 | Aflatoxin: A 50-Year Odyssey of Mechanistic and Translational Toxicology | Toxicological Sciences | 2011 | 519 |
| 21 | The human volatilome: volatile organic compounds (VOCs) in exhaled breath, skin emanations, urine, feces and saliva | Journal of Breath Research | 2014 | 504 |
| 22 | Sex Differences in Autoimmune Disease from a Pathological Perspective | American Journal of Pathology | 2008 | 476 |
| 23 | Emergency Admissions for Cardiovascular and Respiratory Diseases and the Chemical Composition of Fine Particle Air Pollution | Environmental Health Perspectives | 2009 | 450 |
| 24 | Public Health Impacts of Foodborne Mycotoxins | Annual Review of Food Science and Technology | 2014 | 439 |
| 25 | Signal Transducer and Activator of Transcription Factor 6 (Stat6)-deficient Mice Are Protected from Antigen-induced Airway Hyperresponsiveness and Mucus Production | Journal of Experimental Medicine | 1998 | 416 |
| 26 | Nrf2: friend or foe for chemoprevention? | Carcinogenesis | 2010 | 412 |
| 27 | Arsenic Exposure and Prevalence of Type 2 Diabetes in US Adults | JAMA - Journal of the American Medical Association | 2008 | 408 |
| 28 | Oxidative mechanisms in carcinogenesis | British Medical Bulletin | 1993 | 393 |
| 29 | The composition and signaling of the IL-35 receptor are unconventional | Nature Immunology | 2012 | 371 |
| 30 | IL-4 and IL-13 signaling in allergic airway disease | Cytokine | 2015 | 364 |
| 31 | Small Molecule Inhibitor of NRF2 Selectively Intervenes Therapeutic Resistance in KEAP1-Deficient NSCLC Tumors | ACS Chemical Biology | 2016 | 364 |
| 32 | Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity | Biochemical and Biophysical Research Communications | 2006 | 356 |
| 33 | The Role of Keap1 in Cellular Protective Responses | Chemical Research in Toxicology | 2005 | 345 |
| 34 | Decline in NRF2-regulated Antioxidants in Chronic Obstructive Pulmonary Disease Lungs Due to Loss of Its Positive Regulator, DJ-1 | American Journal of Respiratory and Critical Care Medicine | 2008 | 339 |
| 35 | RNAi-Mediated Silencing of Nuclear Factor Erythroid-2–Related Factor 2 Gene Expression in Non–Small Cell Lung Cancer Inhibits Tumor Growth and Increases Efficacy of Chemotherapy | Cancer Research | 2008 | 331 |
| 36 | Prediction of Germline Mutations and Cancer Risk in the Lynch Syndrome | JAMA - Journal of the American Medical Association | 2006 | 328 |
| 37 | Nrf2-dependent protection from LPS induced inflammatory response and mortality by CDDO-Imidazolide | Biochemical and Biophysical Research Communications | 2006 | 321 |
| 38 | Current status of clinical breath analysis | Applied Physics B: Lasers and Optics | 2006 | 321 |
| 39 | Exposure to Electronic Cigarettes Impairs Pulmonary Anti-Bacterial and Anti-Viral Defenses in a Mouse Model | PLoS ONE | 2015 | 321 |
| 40 | Targeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 318 |
| 41 | Blood Cadmium and Lead and Chronic Kidney Disease in US Adults: A Joint Analysis | American Journal of Epidemiology | 2009 | 313 |
| 42 | Evaluation of Murine Norovirus, Feline Calicivirus, Poliovirus, and MS2 as Surrogates for Human Norovirus in a Model of Viral Persistence in Surface Water and Groundwater | Applied and Environmental Microbiology | 2008 | 303 |
| 43 | Evaluation of the Association between Arsenic and Diabetes: A National Toxicology Program Workshop Review | Environmental Health Perspectives | 2012 | 299 |
| 44 | Characterization of BRCA1 and BRCA2 Mutations in a Large United States Sample | Journal of Clinical Oncology | 2006 | 298 |
| 45 | Manganese and Parkinson’s Disease: A Critical Review and New Findings | Environmental Health Perspectives | 2010 | 297 |
| 46 | Effects of Glucosinolate-Rich Broccoli Sprouts on Urinary Levels of Aflatoxin-DNA Adducts and Phenanthrene Tetraols in a Randomized Clinical Trial in He Zuo Township, Qidong, People's Republic of China | Cancer Epidemiology Biomarkers and Prevention | 2005 | 287 |
| 47 | NRF2 Modulates Aryl Hydrocarbon Receptor Signaling: Influence on Adipogenesis | Molecular and Cellular Biology | 2007 | 283 |
| 48 | Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis | Journal of Clinical Investigation | 2013 | 283 |
| 49 | Arsenic Exposure and Cardiovascular Disease:An Updated Systematic Review | Current Atherosclerosis Reports | 2012 | 279 |
| 50 | Keap1–Nrf2 Signaling: A Target for Cancer Prevention by Sulforaphane | Topics in Current Chemistry | 2012 | 272 |
