| HISAT: a fast spliced aligner with low memory requirements | Nature Methods | 2015 | 8K |
| The prescription opioid and heroin crisis: a public health approach to an epidemic of addiction | Annual Review of Public Health | 2015 | 892 |
| Ballgown bridges the gap between transcriptome assembly and expression analysis | Nature Biotechnology | 2015 | 413 |
| Energy balance measurement: when something is not better than nothing | International Journal of Obesity | 2015 | 338 |
| What childhood obesity prevention programmes work? A systematic review and meta-analysis | Obesity Reviews | 2015 | 315 |
| The Bacteroides fragilis toxin gene is prevalent in the colon mucosa of colorectal cancer patients | Clinical Infectious Diseases | 2015 | 289 |
| A targeted real-time early warning score (TREWScore) for septic shock | Science Translational Medicine | 2015 | 279 |
| The relationship of the local food environment with obesity: A systematic review of methods, study quality, and results | Obesity | 2015 | 266 |
| Only three driver gene mutations are required for the development of lung and colorectal cancers | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 248 |
| Exposure to electronic cigarettes impairs pulmonary anti-bacterial and anti-viral defenses in a mouse model | PLoS ONE | 2015 | 241 |
| IL-4 and IL-13 signaling in allergic airway disease | Cytokine | 2015 | 232 |
| Pharmacotherapy for post-traumatic stress disorder: systematic review and meta-analysis | British Journal of Psychiatry | 2015 | 223 |
| Wasted Food: U.S. Consumers' Reported Awareness, Attitudes, and Behaviors | PLoS ONE | 2015 | 216 |
| Frailty and mortality in kidney transplant recipients | American Journal of Transplantation | 2015 | 204 |
| Metabolism links bacterial biofilms and colon carcinogenesis | Cell Metabolism | 2015 | 201 |
| The varying faces of IL-6: From cardiac protection to cardiac failure | Cytokine | 2015 | 190 |
| Telomere dysfunction causes alveolar stem cell failure | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 187 |
| Commercial aquaponics production and profitability: Findings from an international survey | Aquaculture | 2015 | 185 |
| Long non-coding RNA Linc00152 is involved in cell cycle arrest, apoptosis, epithelial to mesenchymal transition, cell migration and invasion in gastric cancer | Cell Cycle | 2015 | 177 |
| Effect of Florida's Prescription Drug Monitoring Program and Pill Mill Laws on Opioid Prescribing and Use | JAMA Internal Medicine | 2015 | 170 |
| Polyester: simulating RNA-seq datasets with differential transcript expression | Bioinformatics | 2015 | 160 |
| mActive: A Randomized Clinical Trial of an Automated mHealth Intervention for Physical Activity Promotion | Journal of the American Heart Association | 2015 | 151 |
| Neighborhood poverty, urban residence, race/ethnicity, and asthma: Rethinking the inner-city asthma epidemic | Journal of Allergy and Clinical Immunology | 2015 | 144 |
| Bacterial infection remodels the DNA methylation landscape of human dendritic cells | Genome Research | 2015 | 138 |
| Diabetes, fasting glucose, and the risk of glaucoma: a meta-analysis | Ophthalmology | 2015 | 134 |
