# | Title | Journal | Year | Citations |
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1 | Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease | Nature | 2012 | 4,038 |
2 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
3 | The complete genome sequence of the Gram-positive bacterium Bacillus subtilis | Nature | 1997 | 3,519 |
4 | A reference panel of 64,976 haplotypes for genotype imputation | Nature Genetics | 2016 | 2,421 |
5 | Consensus Statement: Chromosomal Microarray Is a First-Tier Clinical Diagnostic Test for Individuals with Developmental Disabilities or Congenital Anomalies | American Journal of Human Genetics | 2010 | 2,325 |
6 | Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics | PLoS Genetics | 2014 | 2,012 |
7 | Genetics of rheumatoid arthritis contributes to biology and drug discovery | Nature | 2014 | 1,974 |
8 | Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations | Nature Genetics | 2015 | 1,965 |
9 | Environment dominates over host genetics in shaping human gut microbiota | Nature | 2018 | 1,958 |
10 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
11 | Population-level analysis of gut microbiome variation | Science | 2016 | 1,716 |
12 | Systematic identification of trans eQTLs as putative drivers of known disease associations | Nature Genetics | 2013 | 1,544 |
13 | mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity | Science | 2014 | 1,517 |
14 | Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity | Science | 2016 | 1,398 |
15 | Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity | Science | 2014 | 1,338 |
16 | New genetic loci link adipose and insulin biology to body fat distribution | Nature | 2015 | 1,328 |
17 | The neuroactive potential of the human gut microbiota in quality of life and depression | Nature Microbiology | 2019 | 1,206 |
18 | Genome-wide association study identifies 74 loci associated with educational attainment | Nature | 2016 | 1,204 |
19 | Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits | Nature Genetics | 2018 | 924 |
20 | Biodiversity of plankton by species oscillations and chaos | Nature | 1999 | 871 |
21 | Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses | Nature Genetics | 2016 | 870 |
22 | Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases | Nature Genetics | 2019 | 854 |
23 | Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity | Nature Genetics | 2012 | 848 |
24 | Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects | Nature Genetics | 2017 | 838 |
25 | Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity | Cell | 2016 | 806 |
26 | GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment | Science | 2013 | 750 |
27 | Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity | Nature | 2017 | 743 |
28 | DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis | American Journal of Human Genetics | 2016 | 717 |
29 | Biological interpretation of genome-wide association studies using predicted gene functions | Nature Communications | 2015 | 706 |
30 | Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming | Cell | 2018 | 705 |
31 | Getting up to speed with transcription elongation by RNA polymerase II | Nature Reviews Molecular Cell Biology | 2015 | 692 |
32 | Large-scale association analyses identify host factors influencing human gut microbiome composition | Nature Genetics | 2021 | 676 |
33 | The proteotytic systems of lactic acid bacteria | Antonie Van Leeuwenhoek | 1996 | 672 |
34 | The effect of host genetics on the gut microbiome | Nature Genetics | 2016 | 672 |
35 | Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts | Gut | 2013 | 630 |
36 | Evidence Based Selection of Housekeeping Genes | PLoS ONE | 2007 | 617 |
37 | Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci | Nature Genetics | 2016 | 617 |
38 | Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease | Gut | 2018 | 590 |
39 | Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression | Nature Genetics | 2021 | 590 |
40 | Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture | Nature Genetics | 2013 | 578 |
41 | Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche | Nature | 2014 | 548 |
42 | The transcriptional landscape of age in human peripheral blood | Nature Communications | 2015 | 533 |
43 | Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine | Nature Genetics | 2016 | 520 |
44 | Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis | Nature Genetics | 2016 | 494 |
45 | Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer | Nature Genetics | 2013 | 493 |
46 | Detecting shared pathogenesis from the shared genetics of immune-related diseases | Nature Reviews Genetics | 2009 | 475 |
47 | An Alternative Bactericidal Mechanism of Action for Lantibiotic Peptides That Target Lipid II | Science | 2006 | 459 |
48 | Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk | Nature Genetics | 2017 | 426 |
49 | Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy | Journal of Allergy and Clinical Immunology | 2011 | 424 |
50 | Critical depth and critical turbulence: Two different mechanisms for the development of phytoplankton blooms | Limnology and Oceanography | 1999 | 412 |