| # | Title | Journal | Year | Citations |
|---|
| 1 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
| 2 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 3 | Angiotensin–Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction | New England Journal of Medicine | 2019 | 1,485 |
| 4 | New genetic loci link adipose and insulin biology to body fat distribution | Nature | 2015 | 1,328 |
| 5 | Genome-wide association study identifies 74 loci associated with educational attainment | Nature | 2016 | 1,204 |
| 6 | Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes | Nature Genetics | 2018 | 1,124 |
| 7 | Genome-wide association study identifies eight loci associated with blood pressure | Nature Genetics | 2009 | 1,104 |
| 8 | How to diagnose heart failure with preserved ejection fraction: the HFA–PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) | European Heart Journal | 2019 | 944 |
| 9 | Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits | Nature Genetics | 2018 | 924 |
| 10 | Beneficial effects of long-term intravenous iron therapy with ferric carboxymaltose in patients with symptomatic heart failure and iron deficiency | European Heart Journal | 2015 | 902 |
| 11 | Lenient versus Strict Rate Control in Patients with Atrial Fibrillation | New England Journal of Medicine | 2010 | 851 |
| 12 | Identification of seven loci affecting mean telomere length and their association with disease | Nature Genetics | 2013 | 808 |
| 13 | Increased Central Venous Pressure Is Associated With Impaired Renal Function and Mortality in a Broad Spectrum of Patients With Cardiovascular Disease | Journal of the American College of Cardiology | 2009 | 796 |
| 14 | Angiotensin‐converting enzyme 2 (ACE2), SARS‐CoV‐2 and the pathophysiology of coronavirus disease 2019 (COVID‐19) | Journal of Pathology | 2020 | 791 |
| 15 | Cardiac death and reinfarction after 1 year in the Thrombus Aspiration during Percutaneous coronary intervention in Acute myocardial infarction Study (TAPAS): a 1-year follow-up study | Lancet, The | 2008 | 784 |
| 16 | Proposal for a revised definition of dilated cardiomyopathy, hypokinetic non-dilated cardiomyopathy, and its implications for clinical practice: a position statement of the ESC working group on myocardial and pericardial diseases | European Heart Journal | 2016 | 757 |
| 17 | Renal impairment, worsening renal function, and outcome in patients with heart failure: an updated meta-analysis | European Heart Journal | 2014 | 747 |
| 18 | Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways | Nature Genetics | 2012 | 746 |
| 19 | Genome-wide association analyses identify 18 new loci associated with serum urate concentrations | Nature Genetics | 2013 | 675 |
| 20 | Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture | Nature Genetics | 2013 | 578 |
| 21 | HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials | Lancet, The | 2015 | 562 |
| 22 | Multi-ethnic genome-wide association study for atrial fibrillation | Nature Genetics | 2018 | 552 |
| 23 | A catalog of genetic loci associated with kidney function from analyses of a million individuals | Nature Genetics | 2019 | 549 |
| 24 | Predictors of pregnancy complications in women with congenital heart disease | European Heart Journal | 2010 | 538 |
| 25 | Iron deficiency in chronic heart failure: An international pooled analysis | American Heart Journal | 2013 | 532 |
| 26 | Worsening Renal Function and Prognosis in Heart Failure: Systematic Review and Meta-Analysis | Journal of Cardiac Failure | 2007 | 527 |
| 27 | Mitochondrial function as a therapeutic target in heart failure | Nature Reviews Cardiology | 2017 | 525 |
| 28 | Predictive value of plasma galectin-3 levels in heart failure with reduced and preserved ejection fraction | Annals of Medicine | 2011 | 506 |
| 29 | Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma | Nature Genetics | 2011 | 501 |
| 30 | Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk | Nature Genetics | 2017 | 492 |
| 31 | Clinical practice update on heart failure 2019: pharmacotherapy, procedures, devices and patient management. An expert consensus meeting report of the Heart Failure Association of the European Society of Cardiology | European Journal of Heart Failure | 2019 | 490 |
| 32 | Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure | Nature Communications | 2020 | 466 |
| 33 | Incidence and epidemiology of new onset heart failure with preserved vs. reduced ejection fraction in a community-based cohort: 11-year follow-up of PREVEND | European Heart Journal | 2013 | 451 |
| 34 | Palliative care in heart failure: a position statement from the palliative care workshop of the Heart Failure Association of the European Society of Cardiology | European Journal of Heart Failure | 2009 | 449 |
| 35 | Heart Failure Association of the European Society of Cardiology practical guidance on the use of natriuretic peptide concentrations | European Journal of Heart Failure | 2019 | 446 |
| 36 | Effect of Moderate or Intensive Disease Management Program on Outcome in Patients With Heart Failure<subtitle>Coordinating Study Evaluating Outcomes of Advising and Counseling in Heart Failure (COACH)</subtitle> | Archives of Internal Medicine | 2008 | 443 |
| 37 | The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies | BMC Endocrine Disorders | 2014 | 440 |
| 38 | Type 2 diabetes mellitus and heart failure: a position statement from the Heart Failure Association of the European Society of Cardiology | European Journal of Heart Failure | 2018 | 434 |
| 39 | Compliance in heart failure patients: the importance of knowledge and beliefs | European Heart Journal | 2006 | 433 |
| 40 | Duration of device-detected subclinical atrial fibrillation and occurrence of stroke in ASSERT | European Heart Journal | 2017 | 428 |
| 41 | Beta-blockers for heart failure with reduced, mid-range, and preserved ejection fraction: an individual patient-level analysis of double-blind randomized trials | European Heart Journal | 2018 | 426 |
| 42 | Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function | Nature Communications | 2016 | 412 |
| 43 | Treating oxidative stress in heart failure: past, present and future | European Journal of Heart Failure | 2019 | 407 |
| 44 | Beta-Blockade With Nebivolol in Elderly Heart Failure Patients With Impaired and Preserved Left Ventricular Ejection Fraction | Journal of the American College of Cardiology | 2009 | 405 |
| 45 | New gene functions in megakaryopoiesis and platelet formation | Nature | 2011 | 401 |
| 46 | Decreased cardiac output, venous congestion and the association with renal impairment in patients with cardiac dysfunction | European Journal of Heart Failure | 2007 | 393 |
| 47 | Prognostic value of galectin-3, a novel marker of fibrosis, in patients with chronic heart failure: data from the DEAL-HF study | Clinical Research in Cardiology | 2010 | 393 |
| 48 | Intrathoracic Impedance Monitoring, Audible Patient Alerts, and Outcome in Patients With Heart Failure | Circulation | 2011 | 392 |
| 49 | The kidney in heart failure: an update | European Heart Journal | 2015 | 384 |
| 50 | FTO genotype is associated with phenotypic variability of body mass index | Nature | 2012 | 383 |
