| # | Title | Journal | Year | Citations |
|---|
| 1 | Gut microbiome alterations in Alzheimer’s disease | Scientific Reports | 2017 | 1,256 |
| 2 | Regulation by Small RNAs in Bacteria: Expanding Frontiers | Molecular Cell | 2011 | 1,087 |
| 3 | Influence of culture parameters on lignin metabolism byPhanerochaete chrysosporium | Archives of Microbiology | 1978 | 1,010 |
| 4 | The sigma 70 family: sequence conservation and evolutionary relationships | Journal of Bacteriology | 1992 | 893 |
| 5 | Fungal secondary metabolism: regulation, function and drug discovery | Nature Reviews Microbiology | 2019 | 804 |
| 6 | Direct observation of base-pair stepping by RNA polymerase | Nature | 2005 | 797 |
| 7 | A third recognition element in bacterial promoters: DNA binding by the alpha subunit of RNA polymerase | Science | 1993 | 745 |
| 8 | Thermophilic Microorganisms and Life at High Temperatures | Springer Series in Microbiology | 1978 | 700 |
| 9 | Mapping and sequencing of mutations in the Escherichia colirpoB gene that lead to rifampicin resistance | Journal of Molecular Biology | 1988 | 666 |
| 10 | The htpR gene product of E. coli is a sigma factor for heat-shock promoters | Cell | 1984 | 606 |
| 11 | Transcription Against an Applied Force | Science | 1995 | 571 |
| 12 | Is hsp70 the cellular thermometer? | Trends in Biochemical Sciences | 1991 | 557 |
| 13 | Characterization of an acetate-decarboxylating, non-hydrogen-oxidizing methane bacterium | Archives of Microbiology | 1980 | 555 |
| 14 | Sir2-Dependent Activation of Acetyl-CoA Synthetase by Deacetylation of Active Lysine | Science | 2002 | 541 |
| 15 | Intestinal Microbiota Composition Modulates Choline Bioavailability from Diet and Accumulation of the Proatherogenic Metabolite Trimethylamine- N -Oxide | MBio | 2015 | 535 |
| 16 | Genome, transcriptome, and secretome analysis of wood decay fungus Postia placenta supports unique mechanisms of lignocellulose conversion | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 530 |
| 17 | Aspergillus flavus | Annual Review of Phytopathology | 2011 | 521 |
| 18 | A light-sensing knot revealed by the structure of the chromophore-binding domain of phytochrome | Nature | 2005 | 495 |
| 19 | Global analysis of small RNA and mRNA targets of Hfq | Molecular Microbiology | 2003 | 494 |
| 20 | Peptidases and amino acid catabolism in lactic acid bacteria | Antonie Van Leeuwenhoek | 1999 | 493 |
| 21 | Metabolic network analysis reveals microbial community interactions in anammox granules | Nature Communications | 2017 | 489 |
| 22 | VIBRANT: automated recovery, annotation and curation of microbial viruses, and evaluation of viral community function from genomic sequences | Microbiome | 2020 | 482 |
| 23 | Functional metagenomics reveals diverse β-lactamases in a remote Alaskan soil | ISME Journal | 2009 | 462 |
| 24 | DksA | Cell | 2004 | 444 |
| 25 | Symbiotic Nitrogen Fixation and the Challenges to Its Extension to Nonlegumes | Applied and Environmental Microbiology | 2016 | 443 |
| 26 | The heat shock response of E. coli is regulated by changes in the concentration of σ32 | Nature | 1987 | 442 |
| 27 | Single-Cell Microbiology: Tools, Technologies, and Applications | Microbiology and Molecular Biology Reviews | 2004 | 415 |
| 28 | Bacterial Protection of Beetle-Fungus Mutualism | Science | 2008 | 411 |
| 29 | The biosynthesis of adenosylcobalamin (vitamin B12) | Natural Product Reports | 2002 | 409 |
| 30 | Diet-Microbiota Interactions Mediate Global Epigenetic Programming in Multiple Host Tissues | Molecular Cell | 2016 | 405 |
| 31 | Identification of the sigma E subunit of Escherichia coli RNA polymerase: a second alternate sigma factor involved in high-temperature gene expression. | Genes and Development | 1989 | 403 |
| 32 | A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors | Cell | 2020 | 397 |
| 33 | Transcription Regulation by Initiating NTP Concentration: rRNA Synthesis in Bacteria | Science | 1997 | 377 |
| 34 | Pausing by bacterial RNA polymerase is mediated by mechanistically distinct classes of signals | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 375 |
| 35 | Changing the identity of a tRNA by introducing a G-U wobble pair near the 3' acceptor end | Science | 1988 | 373 |
| 36 | The activity of sigma E, an Escherichia coli heat-inducible sigma-factor, is modulated by expression of outer membrane proteins. | Genes and Development | 1993 | 373 |
| 37 | Community-led, integrated, reproducible multi-omics with anvi’o | Nature Microbiology | 2021 | 370 |
| 38 | Altered promoter recognition by mutant forms of the σ70 subunit of Escherichia coli RNA polymerase | Journal of Molecular Biology | 1989 | 363 |
| 39 | Rules of Engagement: Interspecies Interactions that Regulate Microbial Communities | Annual Review of Microbiology | 2008 | 362 |
| 40 | Dentigerumycin: a bacterial mediator of an ant-fungus symbiosis | Nature Chemical Biology | 2009 | 360 |
| 41 | DnaK, DnaJ, and GrpE heat shock proteins negatively regulate heat shock gene expression by controlling the synthesis and stability of sigma 32. | Genes and Development | 1990 | 351 |
| 42 | Expanded diversity of microbial groups that shape the dissimilatory sulfur cycle | ISME Journal | 2018 | 347 |
| 43 | E.coli Fis protein activates ribosomal RNA transcription in vitro and in vivo. | EMBO Journal | 1990 | 346 |
| 44 | Backtracking by single RNA polymerase molecules observed at near-base-pair resolution | Nature | 2003 | 340 |
| 45 | Calculating solar radiation for ecological studies | Ecological Modelling | 1981 | 339 |
| 46 | AN ABUNDANCE OF RNA REGULATORS | Annual Review of Biochemistry | 2005 | 337 |
| 47 | Structural basis for substrate loading in bacterial RNA polymerase | Nature | 2007 | 333 |
| 48 | Single-Molecule Study of Transcriptional Pausing and Arrest by E. coli RNA Polymerase | Science | 2000 | 330 |
| 49 | Polypeptides containing highly conserved regions of transcription initiation factor σ70 exhibit specificity of binding to promoter DNA | Cell | 1992 | 326 |
| 50 | Catabolite repression of ? amylase gene expression in Bacillus subtilis involves a trans-acting gene product homologous to the Escherichia coli lacl and galR repressors | Molecular Microbiology | 1991 | 322 |
