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Top Articles

#TitleJournalYearCitations
1Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and ObesityCell20081,188
2SV2 Is the Protein Receptor for Botulinum Neurotoxin AScience2006691
3Mechanism of shape determination in motile cellsNature2008658
4How Does Synaptotagmin Trigger Neurotransmitter Release?Annual Review of Biochemistry2008480
5The Hallucinogen N,N -Dimethyltryptamine (DMT) Is an Endogenous Sigma-1 Receptor RegulatorScience2009456
6Maximum velocity of shortening in relation to myosin isoform composition in single fibres from human skeletal muscles.Journal of Physiology1993435
7Synaptotagmin: A Ca2+ sensor that triggers exocytosis?Nature Reviews Molecular Cell Biology2002413
8Improved methodology for analysis and quantitation of proteins on one-dimensional silver-stained slab gelsAnalytical Biochemistry1983399
9SYNAPTIC MECHANISMS FOR CODING TIMING IN AUDITORY NEURONSAnnual Review of Physiology1999379
10MECHANISMS OF HAIR CELL TUNINGAnnual Review of Physiology1999363
11The Sigma Receptor as a Ligand-Regulated Auxiliary Potassium Channel SubunitNeuron2002363
12PIP2 increases the speed of response of synaptotagmin and steers its membrane-penetration activity toward the plasma membraneNature Structural and Molecular Biology2004354
13Reconstitution of Ca2+-Regulated Membrane Fusion by Synaptotagmin and SNAREsScience2004346
14CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpointNature Cell Biology2000343
15Transmembrane Segments of Syntaxin Line the Fusion Pore of Ca2+-Triggered ExocytosisScience2004320
16What's a cerebellar circuit doing in the auditory system?Trends in Neurosciences2004302
17THE ROLE OF TIMING IN THE BRAIN STEM AUDITORY NUCLEI OF VERTEBRATESAnnual Review of Physiology1999297
18Synaptotagmin Modulation of Fusion Pore Kinetics in Regulated Exocytosis of Dense-Core VesiclesScience2001278
19Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cellsJournal of Cell Biology2003278
20Variations in cross-bridge attachment rate and tension with phosphorylation of myosin in mammalian skinned skeletal muscle fibers. Implications for twitch potentiation in intact muscle.Journal of General Physiology1989268
21Reduction in density of transverse tubules and L-type Ca2+ channels in canine tachycardia-induced heart failureCardiovascular Research2001268
22Use of Salsalate to Target Inflammation in the Treatment of Insulin Resistance and Type 2 DiabetesClinical and Translational Science2008254
23Coincidence Detection in the Auditory SystemNeuron1998247
24Mechanisms involved in irreversible anoxic damage to the in vitro rat hippocampal sliceJournal of Physiology1982242
25Three-dimensional structure of vertebrate cardiac muscle myosin filamentsProceedings of the National Academy of Sciences of the United States of America2008232
26The Lateral Superior Olive: A Functional Role in Sound Source LocalizationNeuroscientist2003228
27Glycosylated SV2A and SV2B Mediate the Entry of Botulinum Neurotoxin E into NeuronsMolecular Biology of the Cell2008218
28A Rapid and Specific Ultramicro Method for Total Serum CholesterolClinical Chemistry1962215
29The basal ganglia: An overview of circuits and functionNeuroscience and Biobehavioral Reviews2008203
30Different domains of synaptotagmin control the choice between kiss-and-run and full fusionNature2003200
31Optical lock-in detection imaging microscopy for contrast-enhanced imaging in living cellsProceedings of the National Academy of Sciences of the United States of America2008200
32Somatic sensory representation in the cerebral cortex of the racoon (Procyon lotor)Journal of Comparative Neurology1959199
33Reduced ATP concentration as a basis for synaptic transmission failure during hypoxia in the in vitro guinea‐pig hippocampusJournal of Physiology1982198
34Temperature-Sensitive Paralytic Mutations Demonstrate that Synaptic Exocytosis Requires SNARE Complex Assembly and DisassemblyNeuron1998198
35Analysis of protein interactions using fluorescence technologiesCurrent Opinion in Chemical Biology2003196
36Reduced cortical inhibition in a mouse model of familial childhood absence epilepsyProceedings of the National Academy of Sciences of the United States of America2007192
37Variations in contractile properties of rabbit single muscle fibres in relation to troponin T isoforms and myosin light chains.Journal of Physiology1988191
38Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca2+Nature Structural and Molecular Biology2008182
39Enhancement of Synaptic Efficacy by Presynaptic GABAB ReceptorsNeuron1998180
40Neuropeptide Exocytosis Involving Synaptotagmin-4 and Oxytocin in Hypothalamic Programming of Body Weight and Energy BalanceNeuron2011180
41Drug-induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetineBritish Journal of Pharmacology2006177
42Fusion Pore Dynamics Are Regulated by Synaptotagmin•t-SNARE InteractionsNeuron2004174
43Synaptotagmin-IV modulates synaptic function and long-term potentiation by regulating BDNF releaseNature Neuroscience2009174
44Cardiac IKr Channels Minimally Comprise hERG 1a and 1b SubunitsJournal of Biological Chemistry2004172
45Beta-adrenergic receptor stimulation increases unloaded shortening velocity of skinned single ventricular myocytes from rats.Circulation Research1994167
46Characterization of Outward Currents in Neurons of the Avian Nucleus MagnocellularisJournal of Neurophysiology1998164
47Three distinct kinetic groupings of the synaptotagmin family: Candidate sensors for rapid and delayed exocytosisProceedings of the National Academy of Sciences of the United States of America2005164
48Ca2+–synaptotagmin directly regulates t-SNARE function during reconstituted membrane fusionNature Structural and Molecular Biology2006164
49Two atomic constraints unambiguously position the S4 segment relative to S1 and S2 segments in the closed state of Shaker K channelProceedings of the National Academy of Sciences of the United States of America2007164
50Electrophysiological Actions of Lidocaine on Canine Ventricular Muscle and Purkinje FibersCirculation Research1969163