| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 3 | How many human proteoforms are there? | Nature Chemical Biology | 2018 | 580 |
| 4 | Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys | Nature Communications | 2014 | 579 |
| 5 | Cardiac Repair in a Porcine Model of Acute Myocardial Infarction with Human Induced Pluripotent Stem Cell-Derived Cardiovascular Cells | Cell Stem Cell | 2014 | 407 |
| 6 | The Designer Methcathinone Analogs, Mephedrone and Methylone, are Substrates for Monoamine Transporters in Brain Tissue | Neuropsychopharmacology | 2012 | 386 |
| 7 | Powerful Cocaine-Like Actions of 3,4-Methylenedioxypyrovalerone (MDPV), a Principal Constituent of Psychoactive ‘Bath Salts’ Products | Neuropsychopharmacology | 2013 | 361 |
| 8 | 3D Collagen Alignment Limits Protrusions to Enhance Breast Cancer Cell Persistence | Biophysical Journal | 2014 | 346 |
| 9 | Cytotoxicity of Paclitaxel in Breast Cancer Is due to Chromosome Missegregation on Multipolar Spindles | Science Translational Medicine | 2014 | 298 |
| 10 | Phenotypic heterogeneity of disseminated tumour cells is preset by primary tumour hypoxic microenvironments | Nature Cell Biology | 2017 | 258 |
| 11 | Best practices and benchmarks for intact protein analysis for top-down mass spectrometry | Nature Methods | 2019 | 241 |
| 12 | GATA2 haploinsufficiency caused by mutations in a conserved intronic element leads to MonoMAC syndrome | Blood | 2013 | 209 |
| 13 | Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 207 |
| 14 | Caloric restriction delays age-related methylation drift | Nature Communications | 2017 | 204 |
| 15 | Why the stroma matters in breast cancer | Cell Adhesion and Migration | 2012 | 196 |
| 16 | A Remote GATA2 Hematopoietic Enhancer Drives Leukemogenesis in inv(3)(q21;q26) by Activating EVI1 Expression | Cancer Cell | 2014 | 194 |
| 17 | Meflin-Positive Cancer-Associated Fibroblasts Inhibit Pancreatic Carcinogenesis | Cancer Research | 2019 | 194 |
| 18 | Attenuated BMP1 Function Compromises Osteogenesis, Leading to Bone Fragility in Humans and Zebrafish | American Journal of Human Genetics | 2012 | 192 |
| 19 | Production, safety and efficacy of iPSC-derived mesenchymal stromal cells in acute steroid-resistant graft versus host disease: a phase I, multicenter, open-label, dose-escalation study | Nature Medicine | 2020 | 187 |
| 20 | Dnr1 mutations cause neurodegeneration in Drosophila by activating the innate immune response in the brain | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 179 |
| 21 | Fungal Cytochrome P450 Monooxygenases: Their Distribution, Structure, Functions, Family Expansion, and Evolutionary Origin | Genome Biology and Evolution | 2014 | 179 |
| 22 | Top‐down proteomics in health and disease: Challenges and opportunities | Proteomics | 2014 | 169 |
| 23 | Tumor Cell–Driven Extracellular Matrix Remodeling Drives Haptotaxis during Metastatic Progression | Cancer Discovery | 2016 | 164 |
| 24 | A live cell reporter of exosome secretion and uptake reveals pathfinding behavior of migrating cells | Nature Communications | 2020 | 162 |
| 25 | Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity | Journal of Clinical Investigation | 2012 | 162 |
| 26 | Top-Down Proteomics: Ready for Prime Time? | Analytical Chemistry | 2018 | 159 |
| 27 | Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies | Nucleic Acids Research | 2012 | 157 |
| 28 | Comparable calcium handling of human iPSC-derived cardiomyocytes generated by multiple laboratories | Journal of Molecular and Cellular Cardiology | 2015 | 134 |
| 29 | Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo | Journal of Experimental Medicine | 2013 | 127 |
| 30 | Living in CIN: Mitotic Infidelity and Its Consequences for Tumor Promotion and Suppression | Developmental Cell | 2016 | 121 |
| 31 | ATM kinase inhibition in glial cells activates the innate immune response and causes neurodegeneration in Drosophila | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 120 |
| 32 | Autophagy Driven by a Master Regulator of Hematopoiesis | Molecular and Cellular Biology | 2012 | 119 |
| 33 | Hematopoietic specification from human pluripotent stem cells: current advances and challenges toward de novo generation of hematopoietic stem cells | Blood | 2013 | 117 |
| 34 | A Drosophila model of closed head traumatic brain injury | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 116 |
| 35 | The GATA factor revolution in hematology | Blood | 2017 | 115 |
| 36 | Decoupling the effects of stiffness and fiber density on cellular behaviors via an interpenetrating network of gelatin-methacrylate and collagen | Biomaterials | 2017 | 114 |
| 37 | Top-Down Proteomics of Large Proteins up to 223 kDa Enabled by Serial Size Exclusion Chromatography Strategy | Analytical Chemistry | 2017 | 108 |
| 38 | Pharmacokinetics of Escalating Doses of Oral Psilocybin in Healthy Adults | Clinical Pharmacokinetics | 2017 | 107 |
| 39 | Mechanisms of erythrocyte development and regeneration: implications for regenerative medicine and beyond | Development (Cambridge) | 2018 | 107 |
| 40 | The Human Proteoform Project: Defining the human proteome | Science Advances | 2021 | 106 |
| 41 | The hypoblast (visceral endoderm): an evo-devo perspective | Development (Cambridge) | 2012 | 105 |
| 42 | Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling | Journal of Experimental Medicine | 2013 | 104 |
| 43 | Genetic framework for GATA factor function in vascular biology | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 96 |
| 44 | Top-down Proteomics Reveals Concerted Reductions in Myofilament and Z-disc Protein Phosphorylation after Acute Myocardial Infarction | Molecular and Cellular Proteomics | 2014 | 96 |
| 45 | Death following traumatic brain injury in Drosophila is associated with intestinal barrier dysfunction | ELife | 2015 | 95 |
| 46 | COX-2 modulates mammary tumor progression in response to collagen density | Breast Cancer Research | 2016 | 94 |
| 47 | Collagen Alignment as a Predictor of Recurrence after Ductal Carcinoma In Situ | Cancer Epidemiology Biomarkers and Prevention | 2018 | 94 |
| 48 | Non-human primates as a model for aging | Biochimica Et Biophysica Acta - Molecular Basis of Disease | 2018 | 93 |
| 49 | Collagen Matrix Density Drives the Metabolic Shift in Breast Cancer Cells | EBioMedicine | 2016 | 90 |
| 50 | The Innate Immune Response Transcription Factor Relish Is Necessary for Neurodegeneration in a Drosophila Model of Ataxia-Telangiectasia | Genetics | 2013 | 89 |
