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| Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells | Nature Biotechnology | 2004 | 868 |
| Risk factors for obstructive sleep apnea in adults | JAMA - Journal of the American Medical Association | 2004 | 669 |
| Education. Scientific teaching | Science | 2004 | 635 |
| Unhealthy landscapes: Policy recommendations on land use change and infectious disease emergence | Environmental Health Perspectives | 2004 | 593 |
| Positive health: connecting well-being with biology | Philosophical Transactions of the Royal Society B: Biological Sciences | 2004 | 479 |
| Assay variation confounds the diagnosis of hypovitaminosis D: a call for standardization | Journal of Clinical Endocrinology and Metabolism | 2004 | 465 |
| Dual-agent molecular targeting of the epidermal growth factor receptor (EGFR): combining anti-EGFR antibody with tyrosine kinase inhibitor | Cancer Research | 2004 | 343 |
| Model for end stage liver disease score predicts mortality across a broad spectrum of liver disease | Journal of Hepatology | 2004 | 328 |
| The Future of Family Medicine: a collaborative project of the family medicine community | Annals of Family Medicine | 2004 | 318 |
| Estimating equations for association structures | Statistics in Medicine | 2004 | 311 |
| Reconstitution of Ca2+-regulated membrane fusion by synaptotagmin and SNAREs | Science | 2004 | 302 |
| Development and characterization of an in vivo central venous catheter Candida albicans biofilm model | Infection and Immunity | 2004 | 301 |
| In vivo pharmacodynamic activity of daptomycin | Antimicrobial Agents and Chemotherapy | 2004 | 287 |
| Mutations in the transmembrane natriuretic peptide receptor NPR-B impair skeletal growth and cause acromesomelic dysplasia, type Maroteaux | American Journal of Human Genetics | 2004 | 279 |
| Biological length scale topography enhances cell-substratum adhesion of human corneal epithelial cells | Journal of Cell Science | 2004 | 265 |
| Monitoring and testing dairy herds for metabolic disease | Veterinary Clinics of North America - Food Animal Practice | 2004 | 263 |
| Validity of the alcohol use disorders identification test in college students | Alcoholism: Clinical and Experimental Research | 2004 | 260 |
| The pathogenesis of catheter-related bloodstream infection with noncuffed short-term central venous catheters | Intensive Care Medicine | 2004 | 255 |
| Rituximab as treatment for refractory kidney transplant rejection | American Journal of Transplantation | 2004 | 254 |
| Oligodendroglial modulation of fast axonal transport in a mouse model of hereditary spastic paraplegia | Journal of Cell Biology | 2004 | 248 |
| A challenge to traditional radiation oncology | International Journal of Radiation Oncology Biology Physics | 2004 | 247 |
| Cell-specific, spike timing-dependent plasticities in the dorsal cochlear nucleus | Nature Neuroscience | 2004 | 242 |
| MEPE has the properties of an osteoblastic phosphatonin and minhibin | Bone | 2004 | 229 |
| Resistant hypertension, obesity, sleep apnea, and aldosterone: theory and therapy | Hypertension | 2004 | 214 |
