| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Allergic Rhinitis and its Impact on Asthma (ARIA) 2008* | Allergy: European Journal of Allergy and Clinical Immunology | 2008 | 3,827 |
| 3 | The Montreal Definition and Classification of Gastroesophageal Reflux Disease: A Global Evidence-Based Consensus | American Journal of Gastroenterology | 2006 | 3,207 |
| 4 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 5 | Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the Intensive Care Unit | Critical Care Medicine | 2013 | 3,066 |
| 6 | Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee | Journal of Bone and Mineral Research | 2013 | 2,023 |
| 7 | Clinical Guidelines for the Use of Chronic Opioid Therapy in Chronic Noncancer Pain | Journal of Pain | 2009 | 1,960 |
| 8 | Use of Carotid Ultrasound to Identify Subclinical Vascular Disease and Evaluate Cardiovascular Disease Risk: A Consensus Statement from the American Society of Echocardiography Carotid Intima-Media Thickness Task Force Endorsed by the Society for Vascular Medicine | Journal of the American Society of Echocardiography | 2008 | 1,941 |
| 9 | Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis | Lancet Respiratory Medicine,the | 2019 | 1,866 |
| 10 | The NIH Roadmap Epigenomics Mapping Consortium | Nature Biotechnology | 2010 | 1,705 |
| 11 | Grand challenges in global mental health | Nature | 2011 | 1,654 |
| 12 | Pathophysiology of Sleep Apnea | Physiological Reviews | 2010 | 1,592 |
| 13 | Therapeutic monitoring of vancomycin in adult patients: A consensus review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, and the Society of Infectious Diseases Pharmacists | American Journal of Health-System Pharmacy | 2009 | 1,502 |
| 14 | Efficacy of Varenicline, an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist, vs Placebo or Sustained-Release Bupropion for Smoking CessationA Randomized Controlled Trial | JAMA - Journal of the American Medical Association | 2006 | 1,415 |
| 15 | The Human Serum Metabolome | PLoS ONE | 2011 | 1,378 |
| 16 | A compendium of RNA-binding motifs for decoding gene regulation | Nature | 2013 | 1,281 |
| 17 | Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes | Nature | 2010 | 1,261 |
| 18 | Gut microbiome alterations in Alzheimer’s disease | Scientific Reports | 2017 | 1,256 |
| 19 | An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells | Journal of Immunology | 2010 | 1,248 |
| 20 | Guidelines for Performing a Comprehensive Transthoracic Echocardiographic Examination in Adults: Recommendations from the American Society of Echocardiography | Journal of the American Society of Echocardiography | 2019 | 1,208 |
| 21 | Prospective Surveillance for Invasive Fungal Infections in Hematopoietic Stem Cell Transplant Recipients, 2001–2006: Overview of the Transplant‐Associated Infection Surveillance Network (TRANSNET) Database | Clinical Infectious Diseases | 2010 | 1,194 |
| 22 | Nomenclature Revision for Encapsulated Follicular Variant of Papillary Thyroid Carcinoma | JAMA Oncology | 2016 | 1,192 |
| 23 | Benralizumab, an anti-interleukin-5 receptor α monoclonal antibody, as add-on treatment for patients with severe, uncontrolled, eosinophilic asthma (CALIMA): a randomised, double-blind, placebo-controlled phase 3 trial | Lancet, The | 2016 | 1,070 |
| 24 | In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses | Nature | 2009 | 1,002 |
| 25 | Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase | Nature | 2014 | 989 |
| 26 | Peripheral cytokine and chemokine alterations in depression: a meta‐analysis of 82 studies | Acta Psychiatrica Scandinavica | 2017 | 946 |
| 27 | Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 927 |
| 28 | Guidelines for Diagnosis of Cystic Fibrosis in Newborns through Older Adults: Cystic Fibrosis Foundation Consensus Report | Journal of Pediatrics | 2008 | 904 |
| 29 | Quantitative Analyses of Normal Tissue Effects in the Clinic (QUANTEC): An Introduction to the Scientific Issues | International Journal of Radiation Oncology Biology Physics | 2010 | 879 |
| 30 | CAR-T cell therapy: current limitations and potential strategies | Blood Cancer Journal | 2021 | 871 |
| 31 | Image-guided Tumor Ablation: Standardization of Terminology and Reporting Criteria—A 10-Year Update | Radiology | 2014 | 870 |
| 32 | Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology | Nature Reviews Cancer | 2006 | 868 |
| 33 | The Role of Chest Imaging in Patient Management During the COVID-19 Pandemic | Chest | 2020 | 832 |
| 34 | All-cause mortality attributable to chronic kidney disease: a prospective cohort study based on 462 293 adults in Taiwan | Lancet, The | 2008 | 799 |
| 35 | Alcoholic Hepatitis | New England Journal of Medicine | 2009 | 799 |
| 36 | Clinical Practice Guideline: Tonsillectomy in Children | Otolaryngology - Head and Neck Surgery | 2011 | 788 |
| 37 | Randomized Trial of Omalizumab (Anti-IgE) for Asthma in Inner-City Children | New England Journal of Medicine | 2011 | 783 |
| 38 | Exploring the Effects of Omalizumab in Allergic Asthma | American Journal of Respiratory and Critical Care Medicine | 2013 | 772 |
| 39 | The Infant Nasopharyngeal Microbiome Impacts Severity of Lower Respiratory Infection and Risk of Asthma Development | Cell Host and Microbe | 2015 | 721 |
| 40 | Vancomycin Therapeutic Guidelines: A Summary of Consensus Recommendations from the Infectious Diseases Society of America, the American Society of Health-System Pharmacists, and the Society of Infectious Diseases Pharmacists | Clinical Infectious Diseases | 2009 | 702 |
| 41 | Respiratory and Allergic Health Effects of Dampness, Mold, and Dampness-Related Agents: A Review of the Epidemiologic Evidence | Environmental Health Perspectives | 2011 | 698 |
| 42 | Mesenchymal stem cell–educated macrophages: A novel type of alternatively activated macrophages | Experimental Hematology | 2009 | 686 |
| 43 | Therapy-Induced Senescence in Cancer | Journal of the National Cancer Institute | 2010 | 650 |
| 44 | AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch | Nature Immunology | 2012 | 646 |
| 45 | New trends in gender and mathematics performance: A meta-analysis. | Psychological Bulletin | 2010 | 641 |
| 46 | Effects of Diurnal Variation of Gut Microbes and High-Fat Feeding on Host Circadian Clock Function and Metabolism | Cell Host and Microbe | 2015 | 634 |
| 47 | Radiological Society of North America Expert Consensus Statement on Reporting Chest CT Findings Related to COVID-19. Endorsed by the Society of Thoracic Radiology, the American College of Radiology, and RSNA - Secondary Publication | Journal of Thoracic Imaging | 2020 | 629 |
| 48 | Tethered to the EHR: Primary Care Physician Workload Assessment Using EHR Event Log Data and Time-Motion Observations | Annals of Family Medicine | 2017 | 627 |
| 49 | Role of viral respiratory infections in asthma and asthma exacerbations | Lancet, The | 2010 | 624 |
| 50 | The Search for Endogenous Activators of the Aryl Hydrocarbon Receptor | Chemical Research in Toxicology | 2008 | 621 |
