| # | Title | Journal | Year | Citations |
|---|
| 1 | Paclitaxel Reduces Tumor Growth by Reprogramming Tumor-Associated Macrophages to an M1 Profile in a TLR4-Dependent Manner | Cancer Research | 2018 | 283 |
| 2 | Beneficial effects of colchicine for moderate to severe COVID-19: a randomised, double-blinded, placebo-controlled clinical trial | RMD Open | 2021 | 183 |
| 3 | IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population | Nature Communications | 2017 | 171 |
| 4 | Pyruvate Kinase M2: A Potential Target for Regulating Inflammation | Frontiers in Immunology | 2016 | 129 |
| 5 | Nrf2 as a Potential Mediator of Cardiovascular Risk in Metabolic Diseases | Frontiers in Pharmacology | 2019 | 128 |
| 6 | PKM2 promotes Th17 cell differentiation and autoimmune inflammation by fine-tuning STAT3 activation | Journal of Experimental Medicine | 2020 | 119 |
| 7 | Aldosterone, Inflammation, Immune System, and Hypertension | American Journal of Hypertension | 2021 | 105 |
| 8 | Protective Mechanisms of Butyrate on Inflammatory Bowel Disease | Current Pharmaceutical Design | 2019 | 97 |
| 9 | Endothelial nitric oxide synthase: From biochemistry and gene structure to clinical implications of NOS3 polymorphisms | Gene | 2016 | 95 |
| 10 | Hemolysis during cardiac surgery is associated with increased intravascular nitric oxide consumption and perioperative kidney and intestinal tissue damage | Frontiers in Physiology | 2014 | 94 |
| 11 | Mitochondrial DNA Activates the NLRP3 Inflammasome and Predisposes to Type 1 Diabetes in Murine Model | Frontiers in Immunology | 2017 | 91 |
| 12 | Ang-(1-7) is an endogenous β-arrestin-biased agonist of the AT1 receptor with protective action in cardiac hypertrophy | Scientific Reports | 2017 | 82 |
| 13 | CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice | Science Translational Medicine | 2020 | 80 |
| 14 | Perivascular Adipose Tissue as a Relevant Fat Depot for Cardiovascular Risk in Obesity | Frontiers in Physiology | 2018 | 79 |
| 15 | Gastric S-nitrosothiol formation drives the antihypertensive effects of oral sodium nitrite and nitrate in a rat model of renovascular hypertension | Free Radical Biology and Medicine | 2015 | 71 |
| 16 | TNF-α induces vascular insulin resistance via positive modulation of PTEN and decreased Akt/eNOS/NO signaling in high fat diet-fed mice | Cardiovascular Diabetology | 2016 | 70 |
| 17 | Dysregulation of Midbrain Dopamine System and the Pathophysiology of Schizophrenia | Frontiers in Psychiatry | 2020 | 70 |
| 18 | Toll-like receptor 4 inhibition reduces vascular inflammation in spontaneously hypertensive rats | Life Sciences | 2015 | 69 |
| 19 | Increased mitochondrial ROS generation mediates the loss of the anti‐contractile effects of perivascular adipose tissue in high‐fat diet obese mice | British Journal of Pharmacology | 2017 | 65 |
| 20 | PPAR-γ/IL-10 Axis Inhibits MyD88 Expression and Ameliorates Murine Polymicrobial Sepsis | Journal of Immunology | 2014 | 64 |
| 21 | Inducible Nitric Oxide Synthase as a Possible Target in Hypertension | Current Drug Targets | 2014 | 64 |
| 22 | Constrictor prostanoids and uridine adenosine tetraphosphate: vascular mediators and therapeutic targets in hypertension and diabetes | British Journal of Pharmacology | 2015 | 62 |
| 23 | Chemerin reduces vascular nitric oxide/cGMP signalling in rat aorta: a link to vascular dysfunction in obesity? | Clinical Science | 2014 | 58 |
| 24 | Targeting the minor pocket of C5aR for the rational design of an oral allosteric inhibitor for inflammatory and neuropathic pain relief | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 56 |
| 25 | Therapeutic potential and limitations of cholinergic anti-inflammatory pathway in sepsis | Pharmacological Research | 2017 | 56 |
| 26 | Succinate receptor deficiency attenuates arthritis by reducing dendritic cell traffic and expansion of Th17 cells in the lymph nodes | FASEB Journal | 2018 | 53 |
| 27 | Clinical and pharmacogenetic impact of endothelial nitric oxide synthase polymorphisms on cardiovascular diseases | Nitric Oxide - Biology and Chemistry | 2017 | 52 |
| 28 | Interleukin-10 limits increased blood pressure and vascular RhoA/Rho-kinase signaling in angiotensin II-infused mice | Life Sciences | 2016 | 51 |
| 29 | NLRP3 Inflammasome and Mineralocorticoid Receptors Are Associated with Vascular Dysfunction in Type 2 Diabetes Mellitus | Cells | 2019 | 51 |
| 30 | Consistent antioxidant and antihypertensive effects of oral sodium nitrite in DOCA-salt hypertension | Redox Biology | 2015 | 50 |
| 31 | Cannabidiol attenuates behavioral changes in a rodent model of schizophrenia through 5-HT1A, but not CB1 and CB2 receptors | Pharmacological Research | 2020 | 50 |
| 32 | Quercetin decreases the activity of matrix metalloproteinase-2 and ameliorates vascular remodeling in renovascular hypertension | Atherosclerosis | 2018 | 49 |
| 33 | Targeting IL-33/ST2 signaling: regulation of immune function and analgesia | Expert Opinion on Therapeutic Targets | 2017 | 47 |
| 34 | Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase | PLoS Pathogens | 2016 | 47 |
| 35 | Vascular injury in diabetic db/db mice is ameliorated by atorvastatin: role of Rac1/2-sensitive Nox-dependent pathways | Clinical Science | 2015 | 41 |
| 36 | Neuroimmune Interactions in Schizophrenia: Focus on Vagus Nerve Stimulation and Activation of the Alpha-7 Nicotinic Acetylcholine Receptor | Frontiers in Immunology | 2017 | 41 |
| 37 | Involvement of nuclear factor kappa B in the maintenance of persistent inflammatory hypernociception | Pharmacology Biochemistry and Behavior | 2015 | 40 |
| 38 | Omeprazole impairs vascular redox biology and causes xanthine oxidoreductase-mediated endothelial dysfunction | Redox Biology | 2016 | 40 |
| 39 | Dynamic weight bearing is an efficient and predictable method for evaluation of arthritic nociception and its pathophysiological mechanisms in mice | Scientific Reports | 2015 | 39 |
| 40 | Tissue inhibitor of matrix metalloproteinase-1 polymorphism, plasma TIMP-1 levels, and antihypertensive therapy responsiveness in hypertensive disorders of pregnancy | Pharmacogenomics Journal | 2014 | 38 |
| 41 | Smoking-induced aggravation of experimental arthritis is dependent of aryl hydrocarbon receptor activation in Th17 cells | Arthritis Research and Therapy | 2018 | 38 |
| 42 | Green propolis increases myeloid suppressor cells and CD4+Foxp3+ cells and reduces Th2 inflammation in the lungs after allergen exposure | Journal of Ethnopharmacology | 2020 | 38 |
| 43 | β1-Adrenergic blockers exert antioxidant effects, reduce matrix metalloproteinase activity, and improve renovascular hypertension-induced cardiac hypertrophy | Free Radical Biology and Medicine | 2014 | 37 |
| 44 | Peripheral nitric oxide signaling directly blocks inflammatory pain | Biochemical Pharmacology | 2020 | 37 |
| 45 | The involvement of aldosterone on vascular insulin resistance: implications in obesity and type 2 diabetes | Diabetology and Metabolic Syndrome | 2014 | 35 |
| 46 | Role of the endothelin system in sexual dimorphism in cardiovascular and renal diseases | Life Sciences | 2016 | 35 |
| 47 | Atorvastatin and sildenafil lower blood pressure and improve endothelial dysfunction, but only atorvastatin increases vascular stores of nitric oxide in hypertension | Redox Biology | 2013 | 34 |
| 48 | Oral nitrite circumvents antiseptic mouthwash-induced disruption of enterosalivary circuit of nitrate and promotes nitrosation and blood pressure lowering effect | Free Radical Biology and Medicine | 2016 | 33 |
| 49 | Apocynin and Nox2 regulate NF-κB by modifying thioredoxin-1 redox-state | Scientific Reports | 2016 | 33 |
| 50 | DMH-CBD, a cannabidiol analog with reduced cytotoxicity, inhibits TNF production by targeting NF-kB activity dependent on A2A receptor | Toxicology and Applied Pharmacology | 2019 | 33 |
