# | Title | Journal | Year | Citations |
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1 | Antidepressant‐like effects of cannabidiol in mice: possible involvement of 5‐HT1Areceptors | British Journal of Pharmacology | 2010 | 304 |
2 | 5‐HT1A receptors are involved in the cannabidiol‐induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats | British Journal of Pharmacology | 2009 | 218 |
3 | Mass spectrometry in plant metabolomics strategies: from analytical platforms to data acquisition and processing | Natural Product Reports | 2014 | 149 |
4 | Global chemical analysis of biology by mass spectrometry | Nature Reviews Chemistry | 2017 | 146 |
5 | A proposed sequence of events for cadmium-induced mitochondrial impairment | Journal of Inorganic Biochemistry | 2003 | 136 |
6 | Low expression of CD39 on regulatory T cells as a biomarker for resistance to methotrexate therapy in rheumatoid arthritis | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 125 |
7 | Cannabidiol Induces Rapid and Sustained Antidepressant-Like Effects Through Increased BDNF Signaling and Synaptogenesis in the Prefrontal Cortex | Molecular Neurobiology | 2019 | 124 |
8 | Antidepressant‐like effect induced by systemic and intra‐hippocampal administration of DNA methylation inhibitors | British Journal of Pharmacology | 2011 | 119 |
9 | Exploration of avocado by-products as natural sources of bioactive compounds | PLoS ONE | 2018 | 119 |
10 | Polyelectrolyte–protein complexation driven by charge regulation | Soft Matter | 2009 | 105 |
11 | Prioritizing Natural Product Diversity in a Collection of 146 Bacterial Strains Based on Growth and Extraction Protocols | Journal of Natural Products | 2017 | 105 |
12 | Bee Updated: Current Knowledge on Bee Venom and Bee Envenoming Therapy | Frontiers in Immunology | 2019 | 104 |
13 | Chemerin Regulates Crosstalk Between Adipocytes and Vascular Cells Through Nox | Hypertension | 2015 | 90 |
14 | Melatonin prevents mitochondrial dysfunction and insulin resistance in rat skeletal muscle | Journal of Pineal Research | 2014 | 87 |
15 | P2X7 Receptor Signaling in Stress and Depression | International Journal of Molecular Sciences | 2019 | 84 |
16 | Diclofenac Sodium and Mefenamic Acid: Potent Inducers of the Membrane Permeability Transition in Renal Cortex Mitochondria | Archives of Biochemistry and Biophysics | 1997 | 80 |
17 | Inhibition of iNOS induces antidepressant-like effects in mice: Pharmacological and genetic evidence | Neuropharmacology | 2012 | 74 |
18 | Disruption of Staphylococcus aureus biofilms using rhamnolipid biosurfactants | Journal of Dairy Science | 2017 | 66 |
19 | Assessment of multiple mycotoxins in breakfast cereals available in the Portuguese market | Food Chemistry | 2018 | 66 |
20 | Increased mitochondrial ROS generation mediates the loss of the anti‐contractile effects of perivascular adipose tissue in high‐fat diet obese mice | British Journal of Pharmacology | 2017 | 65 |
21 | Tityus serrulatus venom – A lethal cocktail | Toxicon | 2015 | 64 |
22 | The flavonoid quercetin inhibits titanium dioxide (TiO 2 )-induced chronic arthritis in mice | Journal of Nutritional Biochemistry | 2018 | 63 |
23 | Fluoxetine interacts with the lipid bilayer of the inner membrane in isolated rat brain mitochondria, inhibiting electron transport and F1F0-ATPase activity | Molecular and Cellular Biochemistry | 1999 | 62 |
24 | (+)α-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex I and is as effective as arsenic trioxide or ATRA against acute promyelocytic leukemia in vivo | Leukemia | 2012 | 60 |
25 | Metabolomics to Characterize Adaptive and Signaling Responses in Legume Crops under Abiotic Stresses | ACS Omega | 2020 | 60 |
26 | Development of nitrosyl ruthenium complex-loaded lipid carriers for topical administration: improvement in skin stability and in nitric oxide release by visible light irradiation | Journal of Pharmaceutical and Biomedical Analysis | 2010 | 59 |
27 | Chemerin reduces vascular nitric oxide/cGMP signalling in rat aorta: a link to vascular dysfunction in obesity? | Clinical Science | 2014 | 58 |
28 | Assessment of aflatoxin exposure using serum and urinary biomarkers in São Paulo, Brazil: A pilot study | International Journal of Hygiene and Environmental Health | 2016 | 58 |
29 | Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lymph node metastasis in xenograft tumor models | Molecular Cancer | 2014 | 57 |
30 | Antidepressant-like effects of N-acetyl-L-cysteine in rats | Behavioural Pharmacology | 2008 | 53 |
31 | Acute reversible inactivation of the ventral medial prefrontal cortex induces antidepressant-like effects in rats | Behavioural Brain Research | 2010 | 52 |
32 | Antidepressant- and anticompulsive-like effects of purinergic receptor blockade: Involvement of nitric oxide | European Neuropsychopharmacology | 2013 | 50 |
33 | Decreased endothelial nitric oxide, systemic oxidative stress, and increased sympathetic modulation contribute to hypertension in obese rats | American Journal of Physiology - Heart and Circulatory Physiology | 2014 | 49 |
34 | Ruthenium-nitrite complex as pro-drug releases NO in a tissue and enzyme-dependent way | Nitric Oxide - Biology and Chemistry | 2011 | 48 |
35 | Portuguese children dietary exposure to multiple mycotoxins – An overview of risk assessment under MYCOMIX project | Food and Chemical Toxicology | 2018 | 47 |
36 | Polyphenol-enriched cocoa protects the diabetic retina from glial reaction through the sirtuin pathway | Journal of Nutritional Biochemistry | 2015 | 45 |
37 | Fructose 1,6-bisphosphate, a high-energy intermediate of glycolysis, attenuates experimental arthritis by activating anti-inflammatory adenosinergic pathway | Scientific Reports | 2015 | 44 |
38 | Adipokine Chemerin Bridges Metabolic Dyslipidemia and Alveolar Bone Loss in Mice | Journal of Bone and Mineral Research | 2017 | 43 |
39 | Inhibition of acute nociceptive responses in rats after i.c.v. injection of Thr6 -bradykinin, isolated from the venom of the social wasp, Polybia occidentalis | British Journal of Pharmacology | 2007 | 42 |
40 | The adipokine chemerin augments vascular reactivity to contractile stimuli via activation of the MEK-ERK1/2 pathway | Life Sciences | 2012 | 42 |
41 | Global proteomic and functional analysis of Crotalus durissus collilineatus individual venom variation and its impact on envenoming | Journal of Proteomics | 2019 | 42 |
42 | Brain Oxidative Stress During Experimental Sepsis Is Attenuated by Simvastatin Administration | Molecular Neurobiology | 2017 | 41 |
43 | Acute reversible inactivation of the bed nucleus of stria terminalis induces antidepressant-like effect in the rat forced swimming test | Behavioral and Brain Functions | 2010 | 40 |
44 | Neuronal NOS Inhibitor and Conventional Antidepressant Drugs Attenuate Stress-induced Fos Expression in Overlapping Brain Regions | Cellular and Molecular Neurobiology | 2012 | 40 |
45 | Effect of Charge Regulation and Ion–Dipole Interactions on the Selectivity of Protein–Nanoparticle Binding | Langmuir | 2014 | 40 |
46 | In situ evidence of an alternative oxidase and an uncoupling protein in the respiratory chain of Aspergillus fumigatus | International Journal of Biochemistry and Cell Biology | 2004 | 39 |
47 | Effect of methylene blue-induced photodynamic therapy on a Streptococcus mutans biofilm model | Photodiagnosis and Photodynamic Therapy | 2017 | 39 |
48 | Bioaccumulation of Atrazine in Freshwater Bivalves Anodontites trapesialis (Lamarck, 1819) and Corbicula fluminea (Müller, 1774) | Archives of Environmental Contamination and Toxicology | 2006 | 38 |
49 | Effects of reversible inactivation of the dorsal hippocampus on the behavioral and cardiovascular responses to an aversive conditioned context | Behavioural Pharmacology | 2008 | 38 |
50 | Nanoassisted Laser Desorption-Ionization-MS Imaging of Tumors | Analytical Chemistry | 2012 | 38 |