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Top Articles

#TitleJournalYearCitations
1Metabolic reprogramming for cancer cells and their microenvironment: Beyond the Warburg EffectBiochimica Et Biophysica Acta: Reviews on Cancer2018241
2YTHDF2 promotes the liver cancer stem cell phenotype and cancer metastasis by regulating OCT4 expression via m6A RNA methylationOncogene2020218
3Constructing Fe-MOF-Derived Z-Scheme Photocatalysts with Enhanced Charge Transport: Nanointerface and Carbon Sheath Synergistic EffectACS Applied Materials & Interfaces2020217
4Pan-Asian adapted Clinical Practice Guidelines for the management of patients with metastatic non-small-cell lung cancer: a CSCO–ESMO initiative endorsed by JSMO, KSMO, MOS, SSO and TOSAnnals of Oncology2019214
5Radiomic machine-learning classifiers for prognostic biomarkers of advanced nasopharyngeal carcinomaCancer Letters2017211
6Tumor-Acidity-Cleavable Maleic Acid Amide (TACMAA): A Powerful Tool for Designing Smart Nanoparticles To Overcome Delivery Barriers in Cancer NanomedicineAccounts of Chemical Research2018195
7An Ultralocalized Cas13a Assay Enables Universal and Nucleic Acid Amplification-Free Single-Molecule RNA DiagnosticsACS Nano2021187
8Painful intervertebral disc degeneration and inflammation: from laboratory evidence to clinical interventionsBone Research2021184
9Semiconducting polymer-based nanoparticles with strong absorbance in NIR-II window for in vivo photothermal therapy and photoacoustic imagingBiomaterials2018180
10Strategies to improve tumor penetration of nanomedicines through nanoparticle designWiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology2019180
11Metabolic reprogramming and epigenetic modifications on the path to cancerProtein and Cell2022179
12CT-based radiomics signature: a potential biomarker for preoperative prediction of early recurrence in hepatocellular carcinomaAbdominal Radiology2017177
13Circular RNA circRNA_000203 aggravates cardiac hypertrophy via suppressing miR-26b-5p and miR-140-3p binding to Gata4Cardiovascular Research2020170
14Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic PathwaysCell2019163
15Spatial Targeting of Tumor-Associated Macrophages and Tumor Cells with a pH-Sensitive Cluster Nanocarrier for Cancer ChemoimmunotherapyNano Letters2017158
16Anti-Inflammatory and Intestinal Microbiota Modulation Properties of Jinxiang Garlic (Allium sativum L.) Polysaccharides toward Dextran Sodium Sulfate-Induced ColitisJournal of Agricultural and Food Chemistry2020154
17The development and validation of a CT-based radiomics signature for the preoperative discrimination of stage I-II and stage III-IV colorectal cancerOncotarget2016144
18A linear and large-range pressure sensor based on a graphene/silver nanowires nanobiocomposites network and a hierarchical structural spongeComposites Science and Technology2018142
19Targeting of NLRP3 inflammasome with gene editing for the amelioration of inflammatory diseasesNature Communications2018142
20Long noncoding RNA hotair mediated angiogenesis in nasopharyngeal carcinoma by direct and indirect signaling pathwaysOncotarget2016139
21Preparation and Properties of 3D Printed Alginate–Chitosan Polyion Complex Hydrogels for Tissue EngineeringPolymers2018126
22The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stressesAutophagy2021126
23Rational designs of in vivo CRISPR-Cas delivery systemsAdvanced Drug Delivery Reviews2021125
24A study on infectivity of asymptomatic SARS-CoV-2 carriersRespiratory Medicine2020118
25Fecal microbiota transplantation to treat Parkinson's disease with constipationMedicine (United States)2019114
26Emerging therapies for non-small cell lung cancerJournal of Hematology and Oncology2019111
27Bacterial cytoplasmic membranes synergistically enhance the antitumor activity of autologous cancer vaccinesScience Translational Medicine2021109
28Responsive Nanocarriers as an Emerging Platform for Cascaded Delivery of Nucleic Acids to CancerAdvanced Drug Delivery Reviews2017107
29Genomic Landscape and Immune Microenvironment Features of Preinvasive and Early Invasive Lung AdenocarcinomaJournal of Thoracic Oncology2019105
30IVD progenitor cells: a new horizon for understanding disc homeostasis and repairNature Reviews Rheumatology2019105
31STING-mediated intestinal barrier dysfunction contributes to lethal sepsisEBioMedicine2019104
32The potentiated checkpoint blockade immunotherapy by ROS-responsive nanocarrier-mediated cascade chemo-photodynamic therapyBiomaterials2019103
33HPV-positive status associated with inflamed immune microenvironment and improved response to anti-PD-1 therapy in head and neck squamous cell carcinomaScientific Reports2019103
34ROS-Sensitive Polymeric Nanocarriers with Red Light-Activated Size Shrinkage for Remotely Controlled Drug ReleaseChemistry of Materials2018100
35Expression patterns of immune checkpoints in acute myeloid leukemiaJournal of Hematology and Oncology2020100
36A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementiaAlzheimer's Research and Therapy202199
37TNF-α derived from M2 tumor-associated macrophages promotes epithelial-mesenchymal transition and cancer stemness through the Wnt/β-catenin pathway in SMMC-7721 hepatocellular carcinoma cellsExperimental Cell Research201995
38Specific TP53 subtype as biomarker for immune checkpoint inhibitors in lung adenocarcinomaEBioMedicine202095
39Rod-based urchin-like hollow microspheres of Bi2S3: Facile synthesis, photo-controlled drug release for photoacoustic imaging and chemo-photothermal therapy of tumor ablationBiomaterials202095
40Biomimetic mineralization of carboxymethyl chitosan nanofibers with improved osteogenic activity in vitro and in vivoCarbohydrate Polymers201892
41STING is an essential regulator of heart inflammation and fibrosis in mice with pathological cardiac hypertrophy via endoplasmic reticulum (ER) stressBiomedicine and Pharmacotherapy202089
42A General Strategy for Macrotheranostic Prodrug Activation: Synergy between the Acidic Tumor Microenvironment and Bioorthogonal ChemistryAngewandte Chemie - International Edition202089
43A review on methods for diagnosis of breast cancer cells and tissuesCell Proliferation202087
44Scientific frontiers in faecal microbiota transplantation: joint document of Asia-Pacific Association of Gastroenterology (APAGE) and Asia-Pacific Society for Digestive Endoscopy (APSDE)Gut202085
45Role of uremic toxin indoxyl sulfate in the progression of cardiovascular diseaseLife Sciences201780
46Mesenchymal Stem Cell Senescence and Rejuvenation: Current Status and ChallengesFrontiers in Cell and Developmental Biology202080
47Artificial intelligence quantified tumour-stroma ratio is an independent predictor for overall survival in resectable colorectal cancerEBioMedicine202076
48Chromatin Accessibility Dynamics during Chemical Induction of PluripotencyCell Stem Cell201875
49Red-light-triggered self-destructive mesoporous silica nanoparticles for cascade-amplifying chemo-photodynamic therapy favoring antitumor immune responsesBiomaterials202275
50Microgel assembly: Fabrication, characteristics and application in tissue engineering and regenerative medicineBioactive Materials202273