| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 2 | SCENIC: single-cell regulatory network inference and clustering | Nature Methods | 2017 | 3,086 |
| 3 | Role of PFKFB3-Driven Glycolysis in Vessel Sprouting | Cell | 2013 | 1,117 |
| 4 | Identification of the tumour transition states occurring during EMT | Nature | 2018 | 1,083 |
| 5 | Large-scale genotyping identifies 41 new loci associated with breast cancer risk | Nature Genetics | 2013 | 960 |
| 6 | Hippo–YAP/TAZ signalling in organ regeneration and regenerative medicine | Nature Reviews Molecular Cell Biology | 2019 | 552 |
| 7 | Combined antiangiogenic and anti–PD-L1 therapy stimulates tumor immunity through HEV formation | Science Translational Medicine | 2017 | 541 |
| 8 | Interrogating open issues in cancer precision medicine with patient-derived xenografts | Nature Reviews Cancer | 2017 | 527 |
| 9 | Tumour hypoxia causes DNA hypermethylation by reducing TET activity | Nature | 2016 | 521 |
| 10 | Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer | Nature Genetics | 2013 | 493 |
| 11 | Fatty acid carbon is essential for dNTP synthesis in endothelial cells | Nature | 2015 | 466 |
| 12 | Endothelial Cell Metabolism in Normal and Diseased Vasculature | Circulation Research | 2015 | 462 |
| 13 | FOXO1 couples metabolic activity and growth state in the vascular endothelium | Nature | 2016 | 438 |
| 14 | The metabolism of cancer cells during metastasis | Nature Reviews Cancer | 2021 | 431 |
| 15 | Consensus guidelines for the use and interpretation of angiogenesis assays | Angiogenesis | 2018 | 429 |
| 16 | Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk | Nature Genetics | 2017 | 426 |
| 17 | Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study | Lancet Oncology, The | 2016 | 396 |
| 18 | A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling | Cell Research | 2020 | 391 |
| 19 | Lipogenesis and lipolysis: The pathways exploited by the cancer cells to acquire fatty acids | Progress in Lipid Research | 2013 | 389 |
| 20 | Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer | Nature Genetics | 2020 | 380 |
| 21 | Metabolism of stromal and immune cells in health and disease | Nature | 2014 | 377 |
| 22 | Genome-wide association studies identify four ER negative–specific breast cancer risk loci | Nature Genetics | 2013 | 374 |
| 23 | MET is required for the recruitment of anti-tumoural neutrophils | Nature | 2015 | 359 |
| 24 | Tumor Vessel Normalization by Chloroquine Independent of Autophagy | Cancer Cell | 2014 | 358 |
| 25 | Afatinib versus methotrexate as second-line treatment in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck progressing on or after platinum-based therapy (LUX-Head & Neck 1): an open-label, randomised phase 3 trial | Lancet Oncology, The | 2015 | 358 |
| 26 | Adenoid cystic carcinoma of the head and neck – An update | Oral Oncology | 2015 | 352 |
| 27 | Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis | Cell Metabolism | 2016 | 352 |
| 28 | A single-cell map of intratumoral changes during anti-PD1 treatment of patients with breast cancer | Nature Medicine | 2021 | 330 |
| 29 | Post-Transplantation Lymphoproliferative Disorders in Adults | New England Journal of Medicine | 2018 | 303 |
| 30 | Quantitative radiomics studies for tissue characterization: a review of technology and methodological procedures | British Journal of Radiology | 2017 | 270 |
| 31 | Elevated levels of the angiogenic cytokines basic fibroblast growth factor and vascular endothelial growth factor in sera of cancer patients | British Journal of Cancer | 1997 | 262 |
| 32 | Prognosis of Women With Primary Breast Cancer Diagnosed During Pregnancy: Results From an International Collaborative Study | Journal of Clinical Oncology | 2013 | 261 |
| 33 | The Link Between Angiogenesis and Endothelial Metabolism | Annual Review of Physiology | 2017 | 257 |
| 34 | FGF-dependent metabolic control of vascular development | Nature | 2017 | 256 |
| 35 | YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis | Developmental Cell | 2017 | 249 |
| 36 | The role of fatty acid β-oxidation in lymphangiogenesis | Nature | 2017 | 240 |
| 37 | Oncological management and obstetric and neonatal outcomes for women diagnosed with cancer during pregnancy: a 20-year international cohort study of 1170 patients | Lancet Oncology, The | 2018 | 235 |
| 38 | Dynamic Endothelial Cell Rearrangements Drive Developmental Vessel Regression | PLoS Biology | 2015 | 231 |
| 39 | Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages | Cell Research | 2021 | 229 |
| 40 | Treatment of breast cancer during pregnancy: an observational study | Lancet Oncology, The | 2012 | 224 |
| 41 | Predicting the risk of malignancy in adnexal masses based on the Simple Rules from the International Ovarian Tumor Analysis group | American Journal of Obstetrics and Gynecology | 2016 | 212 |
| 42 | Lipid metabolism in cancer cells under metabolic stress | British Journal of Cancer | 2019 | 212 |
| 43 | The Link between the Multiverse of Immune Microenvironments in Metastases and the Survival of Colorectal Cancer Patients | Cancer Cell | 2018 | 209 |
| 44 | Lipid metabolism in cancer: New perspectives and emerging mechanisms | Developmental Cell | 2021 | 207 |
| 45 | Role of glutamine and interlinked asparagine metabolism in vessel formation | EMBO Journal | 2017 | 195 |
| 46 | ATP13A2 deficiency disrupts lysosomal polyamine export | Nature | 2020 | 193 |
| 47 | Gastrointestinal stromal tumours(GISTs) negative for KIT(CD117 antigen) immunoreactivity | Journal of Pathology | 2004 | 188 |
| 48 | TOPGEAR: A Randomized, Phase III Trial of Perioperative ECF Chemotherapy with or Without Preoperative Chemoradiation for Resectable Gastric Cancer: Interim Results from an International, Intergroup Trial of the AGITG, TROG, EORTC and CCTG | Annals of Surgical Oncology | 2017 | 186 |
| 49 | CRISP-ID: decoding CRISPR mediated indels by Sanger sequencing | Scientific Reports | 2016 | 180 |
| 50 | Filopodia are dispensable for endothelial tip cell guidance | Development (Cambridge) | 2013 | 178 |
