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MRC Centre for Developmental and Biomedical Genetics
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top-articles
MRC Centre for Developmental and Biomedical Genetics
102
(top 1%)
papers
9.3K
(top 1%)
citations
45
(top 1%)
h
-index
94
(top 1%)
g
-index
106
all documents
10.0K
doc citations
1.6K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Guidelines for the use and interpretation of assays for monitoring autophagy
Autophagy
2012
3,122
2
A transgenic zebrafish model of neutrophilic inflammation
Blood
2006
915
3
PINK1 cleavage at position A103 by the mitochondrial protease PARL
Human Molecular Genetics
2011
385
4
A model 450 million years in the making: zebrafish and vertebrate immunity
DMM Disease Models and Mechanisms
2012
307
5
Activation of hypoxia-inducible factor-1α (Hif-1α) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model
Blood
2011
218
6
A novel vertebrate model of
Staphylococcus aureus
infection reveals phagocyte-dependent resistance of zebrafish to non-host specialized pathogens
Cellular Microbiology
2008
185
7
Simultaneous intravital imaging of macrophage and neutrophil behaviour during inflammation using a novel transgenic zebrafish
Thrombosis and Haemostasis
2011
182
8
Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson’s disease factors Pink1 and Parkin
DMM Disease Models and Mechanisms
2008
174
9
Tracking gene expression during zebrafish osteoblast differentiation
Developmental Dynamics
2009
156
10
Differentiated skeletal cells contribute to blastema formation during zebrafish fin regeneration
Development (Cambridge)
2011
133
11
Planar Polarity Specification through Asymmetric Subcellular Localization of Fat and Dachsous
Current Biology
2012
128
12
Zebrafish as a new animal model for movement disorders
Journal of Neurochemistry
2008
121
13
Oxazolone-Induced Enterocolitis in Zebrafish Depends on the Composition of the Intestinal Microbiota
Gastroenterology
2009
121
14
Burkholderia cenocepacia
Creates an Intramacrophage Replication Niche in Zebrafish Embryos, Followed by Bacterial Dissemination and Establishment of Systemic Infection
Infection and Immunity
2010
121
15
Prdm1‐ and Sox6‐mediated transcriptional repression specifies muscle fibre type in the zebrafish embryo
EMBO Reports
2008
119
16
Neutrophil-mediated tumour angiogenesis: Subversion of immune responses to promote tumour growth
Seminars in Cancer Biology
2013
119
17
A role for the Myoblast city homologues Dock1 and Dock5 and the adaptor proteins Crk and Crk-like in zebrafish myoblast fusion
Development (Cambridge)
2007
118
18
The PINK1/Parkin pathway: a mitochondrial quality control system?
Journal of Bioenergetics and Biomembranes
2009
118
19
Neutrophil-Delivered Myeloperoxidase Dampens the Hydrogen Peroxide Burst after Tissue Wounding in Zebrafish
Current Biology
2012
117
20
Pivotal Advance: Pharmacological manipulation of inflammation resolution during spontaneously resolving tissue neutrophilia in the zebrafish
Journal of Leukocyte Biology
2009
115
21
Dynamics of Core Planar Polarity Protein Turnover and Stable Assembly into Discrete Membrane Subdomains
Developmental Cell
2011
115
22
Regulation of Zebrafish Skeletogenesis by ext2/dackel and papst1/pinscher
PLoS Genetics
2008
114
23
Identification of compounds with anti-convulsant properties in a zebrafish model of epileptic seizures
DMM Disease Models and Mechanisms
2012
110
24
Live Imaging of Tumor Initiation in Zebrafish Larvae Reveals a Trophic Role for Leukocyte-Derived PGE2
Current Biology
2012
109
25
Loss of nuclear
TDP
‐43 in amyotrophic lateral sclerosis (
ALS
) causes altered expression of splicing machinery and widespread dysregulation of
RNA
splicing in motor neurones
Neuropathology and Applied Neurobiology
2014
98
26
Analysis of Pax7 expressing myogenic cells in zebrafish muscle development, injury, and models of disease
Developmental Dynamics
2011
95
27
Disrupted-in-schizophrenia 1 and neuregulin 1 are required for the specification of oligodendrocytes and neurones in the zebrafish brain
Human Molecular Genetics
2009
84
28
Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport
Nature Cell Biology
2014
84
29
The Frizzled-dependent planar polarity pathway locally promotes E-cadherin turnover via recruitment of RhoGEF2
Development (Cambridge)
2013
80
30
Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin
Cell Death and Differentiation
2009
77
31
From the cytoplasm into the cilium: Bon voyage
Organogenesis
2014
72
32
A Zebrafish Model to Study and Therapeutically Manipulate Hypoxia Signaling in Tumorigenesis
Cancer Research
2012
71
33
The Complex I Subunit NDUFA10 Selectively Rescues Drosophila pink1 Mutants through a Mechanism Independent of Mitophagy
PLoS Genetics
2014
68
34
Gradients of signalling in the developing limb
Current Opinion in Cell Biology
2012
67
35
Development of the Medial Hypothalamus
Current Topics in Developmental Biology
2013
67
36
Ischemia Is Not Required for Arteriogenesis in Zebrafish Embryos
Arteriosclerosis, Thrombosis, and Vascular Biology
2007
62
37
The epigenetic regulator Histone Deacetylase 1 promotes transcription of a core neurogenic programme in zebrafish embryos
BMC Genomics
2011
60
38
Sdf1a patterns zebrafish melanophores and links the somite and melanophore pattern defects in choker mutants
Development (Cambridge)
2007
59
39
Targeted mutation of the
talpid3
gene in zebrafish reveals its conserved requirement for ciliogenesis and Hedgehog signalling across the vertebrates
Development (Cambridge)
2011
57
40
Collagen XV, a novel factor in zebrafish notochord differentiation and muscle development
Developmental Biology
2008
55
41
How could Parkin-mediated ubiquitination of mitofusin promote mitophagy?
Autophagy
2010
55
42
Repelled from the wound, or randomly dispersed? Reverse migration behaviour of neutrophils characterized by dynamic modelling
Journal of the Royal Society Interface
2012
55
43
Tnfa Signaling Through Tnfr2 Protects Skin Against Oxidative Stress–Induced Inflammation
PLoS Biology
2014
55
44
RA and FGF Signalling Are Required in the Zebrafish Otic Vesicle to Pattern and Maintain Ventral Otic Identities
PLoS Genetics
2014
49
45
Gli2a protein localization reveals a role for Iguana/DZIP1 in primary ciliogenesis and a dependence of Hedgehog signal transduction on primary cilia in the zebrafish
BMC Biology
2010
48
46
Genetic and chemical modulation of spastin-dependent axon outgrowth in zebrafish embryos indicates a role for impaired microtubule dynamics in hereditary spastic paraplegia
DMM Disease Models and Mechanisms
2010
48
47
Positive and Negative Regulation of Gli Activity by Kif7 in the Zebrafish Embryo
PLoS Genetics
2013
46
48
Blood flow suppresses vascular Notch signalling via dll4 and is required for angiogenesis in response to hypoxic signalling
Cardiovascular Research
2013
45
49
The polycomb group protein EZH2 regulates actin polymerization in human prostate cancer cells
Prostate
2008
44
50
FatJ acts via the Hippo mediator Yap1 to restrict the size of neural progenitor cell pools
Development (Cambridge)
2011
43
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