Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase | Nature | 2005 | 3.5K |
Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015: A Systematic Analysis for the Global Burden of Disease Study | JAMA Oncology | 2017 | 2.4K |
Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus | Cell | 2020 | 2.3K |
Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK | Lancet, The | 2021 | 2.1K |
Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 2K |
Genome-wide association study identifies novel breast cancer susceptibility loci | Nature | 2007 | 2K |
Succinate is an inflammatory signal that induces IL-1β through HIF-1α | Nature | 2013 | 1.9K |
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes | Science | 2007 | 1.8K |
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions | Nature | 2005 | 1.7K |
Stem cell ageing: does it happen and can we intervene? | Expert Reviews in Molecular Medicine | 2007 | 1.5K |
World-wide projections for hip fracture | Osteoporosis International | 1997 | 1.3K |
SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues | Cell | 2020 | 1.3K |
The role of myeloid cells in the promotion of tumour angiogenesis | Nature Reviews Cancer | 2008 | 1.2K |
Local dispersal promotes biodiversity in a real-life game of rock-paper-scissors | Nature | 2002 | 1.2K |
Competency-based medical education: theory to practice | Medical Teacher | 2010 | 1.1K |
Predictive value of BMD for hip and other fractures | Journal of Bone and Mineral Research | 2005 | 1K |
Guidelines for the welfare and use of animals in cancer research | British Journal of Cancer | 2010 | 1K |
Global, regional, and national burden of neurological disorders during 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015 | Lancet Neurology, The | 2017 | 984 |
Sample size of 12 per group rule of thumb for a pilot study | Pharmaceutical Statistics | 2005 | 979 |
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci | Nature Genetics | 2010 | 969 |
The use of sacs of everted small intestine for the study of the transference of substances from the mucosal to the serosal surface | Journal of Physiology | 1954 | 957 |
The interleukin-1 genotype as a severity factor in adult periodontal disease | Journal of Clinical Periodontology | 1997 | 926 |
Hypoglycemia and diabetes: a report of a workgroup of the American Diabetes Association and the Endocrine Society | Diabetes Care | 2013 | 920 |
Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras | Journal of Bone and Mineral Research | 1998 | 898 |
European guidance for the diagnosis and management of osteoporosis in postmenopausal women | Osteoporosis International | 2013 | 885 |