| # | Title | Journal | Year | Citations |
|---|
| 1 | Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Nature Genetics | 2019 | 1,962 |
| 2 | New insights into the genetic etiology of Alzheimer’s disease and related dementias | Nature Genetics | 2022 | 700 |
| 3 | Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa | Nature Genetics | 2019 | 641 |
| 4 | Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis | Lancet Neurology, The | 2015 | 432 |
| 5 | Editorial: The Role of Calcium Handling in Heart Failure and Heart Failure Associated Arrhythmias | Frontiers in Physiology | 2019 | 309 |
| 6 | The central vein sign and its clinical evaluation for the diagnosis of multiple sclerosis: a consensus statement from the North American Imaging in Multiple Sclerosis Cooperative | Nature Reviews Neurology | 2016 | 274 |
| 7 | Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference | Nature Communications | 2018 | 263 |
| 8 | Separate Mechanisms for Perception of Numerosity and Density | Psychological Science | 2014 | 178 |
| 9 | Opportunities for the repurposing of PARP inhibitors for the therapy of non‐oncological diseases | British Journal of Pharmacology | 2018 | 160 |
| 10 | The Vascular Impairment of Cognition Classification Consensus Study | Alzheimer's and Dementia | 2017 | 143 |
| 11 | Purinergic signalling in brain ischemia | Neuropharmacology | 2016 | 135 |
| 12 | Inhibition of α9α10 nicotinic acetylcholine receptors prevents chemotherapy-induced neuropathic pain | Proceedings of the National Academy of Sciences of the United States of America | 2017 | 135 |
| 13 | Heterozygous TREM2 mutations in frontotemporal dementia | Neurobiology of Aging | 2014 | 134 |
| 14 | Advances in the structural annotation of human carbonic anhydrases and impact on future drug discovery | Expert Opinion on Drug Discovery | 2019 | 123 |
| 15 | Circulating Oxidative Stress Biomarkers in Clinical Studies on Type 2 Diabetes and Its Complications | Oxidative Medicine and Cellular Longevity | 2019 | 117 |
| 16 | Autologous haematopoietic stem cell transplantation with an intermediate intensity conditioning regimen in multiple sclerosis: the Italian multi-centre experience | Multiple Sclerosis Journal | 2012 | 115 |
| 17 | The C9orf72 repeat expansion itself is methylated in ALS and FTLD patients | Acta Neuropathologica | 2015 | 114 |
| 18 | EFNS‐ENS/EAN Guideline on concomitant use of cholinesterase inhibitors and memantine in moderate to severe Alzheimer's disease | European Journal of Neurology | 2015 | 110 |
| 19 | Historical evolution of the concept of anorexia nervosa and relationships with orthorexia nervosa, autism, and obsessive-compulsive spectrum | Neuropsychiatric Disease and Treatment | 2016 | 109 |
| 20 | Visual sustained attention and numerosity sensitivity correlate with math achievement in children | Journal of Experimental Child Psychology | 2013 | 108 |
| 21 | Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia | Journal of Neurology, Neurosurgery and Psychiatry | 2020 | 106 |
| 22 | Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs–CAIs) for the Treatment of Rheumatoid Arthritis | Journal of Medicinal Chemistry | 2017 | 104 |
| 23 | Different coding strategies for the perception of stable and changeable facial attributes | Scientific Reports | 2016 | 102 |
| 24 | α-Conotoxin RgIA protects against the development of nerve injury-induced chronic pain and prevents both neuronal and glial derangement | Pain | 2014 | 100 |
| 25 | Olive polyphenols: new promising agents to combat aging-associated neurodegeneration | Expert Review of Neurotherapeutics | 2017 | 99 |
| 26 | Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study | Lancet Neurology, The | 2018 | 97 |
| 27 | Long-term effects of monocular deprivation revealed with binocular rivalry gratings modulated in luminance and in color | Journal of Vision | 2013 | 95 |
| 28 | Neuroendocrinology and brain imaging of reward in eating disorders: A possible key to the treatment of anorexia nervosa and bulimia nervosa | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2018 | 95 |
| 29 | Solid lipid nanoparticles for delivery of andrographolide across the blood-brain barrier: in vitro and in vivo evaluation | Colloids and Surfaces B: Biointerfaces | 2018 | 95 |
| 30 | Olive Polyphenols: Antioxidant and Anti-Inflammatory Properties | Antioxidants | 2021 | 92 |
| 31 | Effects of natural and synthetic isothiocyanate-based H 2 S-releasers against chemotherapy-induced neuropathic pain: Role of Kv7 potassium channels | Neuropharmacology | 2017 | 90 |
| 32 | Exosomes secreted from human colon cancer cells influence the adhesion of neighboring metastatic cells: Role of microRNA-210 | Cancer Biology and Therapy | 2016 | 89 |
| 33 | Nutritionally relevant concentrations of resveratrol and hydroxytyrosol mitigate oxidative burst of human granulocytes and monocytes and the production of pro-inflammatory mediators in LPS-stimulated RAW 264.7 macrophages | International Immunopharmacology | 2017 | 89 |
| 34 | De Novo Pathogenic Variants in CACNA1E Cause Developmental and Epileptic Encephalopathy with Contractures, Macrocephaly, and Dyskinesias | American Journal of Human Genetics | 2018 | 87 |
| 35 | Mutation analysis ofCHCHD10in different neurodegenerative diseases | Brain | 2015 | 86 |
| 36 | Nanoscale Ion Emitters in Native Mass Spectrometry for Measuring Ligand–Protein Binding Affinities | ACS Central Science | 2019 | 84 |
| 37 | Antineuropathic Profile of N-Palmitoylethanolamine in a Rat Model of Oxaliplatin-Induced Neurotoxicity | PLoS ONE | 2015 | 81 |
| 38 | Development of solid lipid nanoparticles as carriers for improving oral bioavailability of glibenclamide | European Journal of Pharmaceutics and Biopharmaceutics | 2016 | 80 |
| 39 | Adult Autism Subthreshold Spectrum (AdAS Spectrum): Validation of a questionnaire investigating subthreshold autism spectrum | Comprehensive Psychiatry | 2017 | 79 |
| 40 | Preventing adolescent stress-induced cognitive and microbiome changes by diet | Proceedings of the National Academy of Sciences of the United States of America | 2019 | 79 |
| 41 | Hyperactive mTOR pathway promotes lymphoproliferation and abnormal differentiation in autoimmune lymphoproliferative syndrome | Blood | 2016 | 77 |
| 42 | Who has the worst attitudes toward sexual minorities? Comparison of transphobia and homophobia levels in gender dysphoric individuals, the general population and health care providers | Journal of Endocrinological Investigation | 2017 | 75 |
| 43 | Hypermethylation of the CpG-island near the C9orf72 G4C2-repeat expansion in FTLD patients | Human Molecular Genetics | 2014 | 74 |
| 44 | The pharmacological basis of opioids | Clinical Cases in Mineral and Bone Metabolism | 2015 | 74 |
| 45 | Amelioration of diastolic dysfunction by dapagliflozin in a non-diabetic model involves coronary endothelium | Pharmacological Research | 2020 | 74 |
| 46 | Effects of ranolazine in a model of doxorubicin‐induced left ventricle diastolic dysfunction | British Journal of Pharmacology | 2017 | 73 |
| 47 | Effect of Mediterranean Diet Enriched in High Quality Extra Virgin Olive Oil on Oxidative Stress, Inflammation and Gut Microbiota in Obese and Normal Weight Adult Subjects | Frontiers in Pharmacology | 2019 | 72 |
| 48 | The novel H 2 S-donor 4-carboxyphenyl isothiocyanate promotes cardioprotective effects against ischemia/reperfusion injury through activation of mitoK ATP channels and reduction of oxidative stress | Pharmacological Research | 2016 | 71 |
| 49 | Nonalcoholic steatohepatitis as a novel player in metabolic syndrome-induced erectile dysfunction: An experimental study in the rabbit | Molecular and Cellular Endocrinology | 2014 | 70 |
| 50 | From Subjective Cognitive Decline to Alzheimer’s Disease: The Predictive Role of Neuropsychological Assessment, Personality Traits, and Cognitive Reserve. A 7-Year Follow-Up Study | Journal of Alzheimer's Disease | 2018 | 68 |
