# | Title | Journal | Year | Citations |
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1 | Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and βAPP processing | Nature | 2000 | 895 |
2 | Cognitive Dysfunction in Early-Onset Multiple Sclerosis | Archives of Neurology | 2001 | 586 |
3 | Multiple sclerosis-related cognitive changes: A review of cross-sectional and longitudinal studies | Journal of the Neurological Sciences | 2006 | 465 |
4 | Quality of life in multiple sclerosis: the impact of depression, fatigue and disability | Multiple Sclerosis Journal | 2001 | 409 |
5 | The Rao’s Brief Repeatable Battery and Stroop test: normative values with age, education and gender corrections in an Italian population | Multiple Sclerosis Journal | 2006 | 343 |
6 | Cognitive Impairment in Early-Onset Multiple Sclerosis | Archives of Neurology | 1995 | 329 |
7 | Cognitive impairment in multiple sclerosis: clinical management, MRI, and therapeutic avenues | Lancet Neurology, The | 2020 | 302 |
8 | Neocortical volume decrease in relapsing–remitting MS patients with mild cognitive impairment | Neurology | 2004 | 293 |
9 | Radiologically Isolated Syndrome: 5-Year Risk for an Initial Clinical Event | PLoS ONE | 2014 | 254 |
10 | New natural history of interferon-β-treated relapsing multiple sclerosis | Annals of Neurology | 2007 | 251 |
11 | Cognitive and psychosocial features of childhood and juvenile MS | Neurology | 2008 | 251 |
12 | Association of Neocortical Volume Changes With Cognitive Deterioration in Relapsing-Remitting Multiple Sclerosis | Archives of Neurology | 2007 | 203 |
13 | Cognitive and psychosocial features in childhood and juvenile MS | Neurology | 2010 | 198 |
14 | Clinical Pharmacokinetics of Valproic Acid - 1988 | Clinical Pharmacokinetics | 1988 | 181 |
15 | Cognitive impairment and its relation with disease measures in mildly disabled patients with relapsing–remitting multiple sclerosis: baseline results from the Cognitive Impairment in Multiple Sclerosis (COGIMUS) study | Multiple Sclerosis Journal | 2009 | 172 |
16 | Association of MRI metrics and cognitive impairment in radiologically isolated syndromes | Neurology | 2012 | 169 |
17 | Geographical Variations in Sex Ratio Trends over Time in Multiple Sclerosis | PLoS ONE | 2012 | 166 |
18 | Establishing pathological cut-offs of brain atrophy rates in multiple sclerosis | Journal of Neurology, Neurosurgery and Psychiatry | 2016 | 162 |
19 | Relevance of cognitive deterioration in early relapsing-remitting MS: a 3-year follow-up study | Multiple Sclerosis Journal | 2010 | 157 |
20 | Cognitive impairment in early stages of multiple sclerosis | Neurological Sciences | 2010 | 153 |
21 | Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease | European Journal of Human Genetics | 2006 | 152 |
22 | Predictors and dynamics of postpartum relapses in women with multiple sclerosis | Multiple Sclerosis Journal | 2014 | 148 |
23 | Benign multiple sclerosis | Journal of Neurology | 2006 | 147 |
24 | Cognitive impairment predicts conversion to multiple sclerosis in clinically isolated syndromes | Multiple Sclerosis Journal | 2010 | 144 |
25 | Glial fibrillary acidic protein in cryogenic lesions of the rat brain | Neuroscience Letters | 1981 | 143 |
26 | Pregnancy and fetal outcomes after interferon-β exposure in multiple sclerosis | Neurology | 2010 | 142 |
27 | Cognitive changes in multiple sclerosis | Expert Review of Neurotherapeutics | 2008 | 141 |
28 | Breastfeeding is not related to postpartum relapses in multiple sclerosis | Neurology | 2011 | 135 |
29 | Real‐life impact of early interferonβ therapy in relapsing multiple sclerosis | Annals of Neurology | 2009 | 132 |
30 | Interrater Reliability in Assessing Functional Systems and Disability on the Kurtzke Scale in Multiple Sclerosis | Archives of Neurology | 1988 | 130 |
31 | Primary Progressive Multiple Sclerosis Evolving From Radiologically Isolated Syndrome | Annals of Neurology | 2016 | 130 |
32 | Male Sex Is Independently Associated with Faster Disability Accumulation in Relapse-Onset MS but Not in Primary Progressive MS | PLoS ONE | 2015 | 122 |
33 | Incidence of stroke in young adults in Florence, Italy. | Stroke | 1988 | 115 |
34 | Cognitive reserve and cortical atrophy in multiple sclerosis | Neurology | 2013 | 113 |
35 | A prospective study on the natural history of multiple sclerosis: clues to the conduct and interpretation of clinical trials | Journal of the Neurological Sciences | 1999 | 112 |
36 | Coping strategies, psychological variables and their relationship with quality of life in multiple sclerosis | Neurological Sciences | 2009 | 110 |
37 | A multicentre follow-up study of 1152 patients with myasthenia gravis in Italy | Journal of Neurology | 1990 | 108 |
38 | Cognitive assessment and quantitative magnetic resonance metrics can help to identify benign multiple sclerosis | Neurology | 2008 | 104 |
39 | Ecology of Viruses Isolated from Sand Flies in Italy and Characterization of a New Phlebovirus (Arbia Virus) | American Journal of Tropical Medicine and Hygiene | 1988 | 102 |
40 | A prospective study on the prognosis of multiple sclerosis | Neurological Sciences | 2000 | 94 |
41 | Neuropsychological and MRI measures predict short-term evolution in benign multiple sclerosis | Neurology | 2009 | 90 |
42 | Effects of immunomodulatory treatment with subcutaneous interferon beta-1a oncognitive decline in mildly disabled patients with relapsing—remitting multiple sclerosis | Multiple Sclerosis Journal | 2010 | 89 |
43 | Coping strategies, cognitive impairment, psychological variables and their relationship with quality of life in multiple sclerosis | Neurological Sciences | 2010 | 87 |
44 | Long-Term Adherence to Interferon β Therapy in Relapsing-Remitting Multiple Sclerosis | European Neurology | 2008 | 86 |
45 | The different apoptotic potential of the p53 codon 72 alleles increases with age and modulates in vivo ischaemia-induced cell death | Cell Death and Differentiation | 2004 | 84 |
46 | Oxidative Stress and a Key Metabolic Enzyme in Alzheimer Brains, Cultured Cells, and an Animal Model of Chronic Oxidative Deficits | Annals of the New York Academy of Sciences | 1999 | 82 |
47 | Pregnancy and fetal outcomes after Glatiramer Acetate exposure in patients with multiple sclerosis: a prospective observational multicentric study | BMC Neurology | 2012 | 82 |
48 | Impact of Natalizumab on Cognitive Performances and Fatigue in Relapsing Multiple Sclerosis: A Prospective, Open-Label, Two Years Observational Study | PLoS ONE | 2012 | 82 |
49 | EFFECT OF PHOSPHATIDYLSERINE ON ACETYLCHOLINE OUTPUT FROM THE CEREBRAL CORTEX OF THE RAT | Journal of Neurochemistry | 1979 | 80 |
50 | Epidural analgesia and cesarean delivery in multiple sclerosis post-partum relapses: the Italian cohort study | BMC Neurology | 2012 | 78 |