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Top Articles

#TitleJournalYearCitations
1Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and βAPP processingNature2000895
2Cognitive Dysfunction in Early-Onset Multiple SclerosisArchives of Neurology2001586
3Multiple sclerosis-related cognitive changes: A review of cross-sectional and longitudinal studiesJournal of the Neurological Sciences2006465
4Quality of life in multiple sclerosis: the impact of depression, fatigue and disabilityMultiple Sclerosis Journal2001409
5The Rao’s Brief Repeatable Battery and Stroop test: normative values with age, education and gender corrections in an Italian populationMultiple Sclerosis Journal2006343
6Cognitive Impairment in Early-Onset Multiple SclerosisArchives of Neurology1995329
7Cognitive impairment in multiple sclerosis: clinical management, MRI, and therapeutic avenuesLancet Neurology, The2020302
8Neocortical volume decrease in relapsing–remitting MS patients with mild cognitive impairmentNeurology2004293
9Radiologically Isolated Syndrome: 5-Year Risk for an Initial Clinical EventPLoS ONE2014254
10New natural history of interferon-β-treated relapsing multiple sclerosisAnnals of Neurology2007251
11Cognitive and psychosocial features of childhood and juvenile MSNeurology2008251
12Association of Neocortical Volume Changes With Cognitive Deterioration in Relapsing-Remitting Multiple SclerosisArchives of Neurology2007203
13Cognitive and psychosocial features in childhood and juvenile MSNeurology2010198
14Clinical Pharmacokinetics of Valproic Acid - 1988Clinical Pharmacokinetics1988181
15Cognitive impairment and its relation with disease measures in mildly disabled patients with relapsing–remitting multiple sclerosis: baseline results from the Cognitive Impairment in Multiple Sclerosis (COGIMUS) studyMultiple Sclerosis Journal2009172
16Association of MRI metrics and cognitive impairment in radiologically isolated syndromesNeurology2012169
17Geographical Variations in Sex Ratio Trends over Time in Multiple SclerosisPLoS ONE2012166
18Establishing pathological cut-offs of brain atrophy rates in multiple sclerosisJournal of Neurology, Neurosurgery and Psychiatry2016162
19Relevance of cognitive deterioration in early relapsing-remitting MS: a 3-year follow-up studyMultiple Sclerosis Journal2010157
20Cognitive impairment in early stages of multiple sclerosisNeurological Sciences2010153
21Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's diseaseEuropean Journal of Human Genetics2006152
22Predictors and dynamics of postpartum relapses in women with multiple sclerosisMultiple Sclerosis Journal2014148
23Benign multiple sclerosisJournal of Neurology2006147
24Cognitive impairment predicts conversion to multiple sclerosis in clinically isolated syndromesMultiple Sclerosis Journal2010144
25Glial fibrillary acidic protein in cryogenic lesions of the rat brainNeuroscience Letters1981143
26Pregnancy and fetal outcomes after interferon-β exposure in multiple sclerosisNeurology2010142
27Cognitive changes in multiple sclerosisExpert Review of Neurotherapeutics2008141
28Breastfeeding is not related to postpartum relapses in multiple sclerosisNeurology2011135
29Real‐life impact of early interferonβ therapy in relapsing multiple sclerosisAnnals of Neurology2009132
30Interrater Reliability in Assessing Functional Systems and Disability on the Kurtzke Scale in Multiple SclerosisArchives of Neurology1988130
31Primary Progressive Multiple Sclerosis Evolving From Radiologically Isolated SyndromeAnnals of Neurology2016130
32Male Sex Is Independently Associated with Faster Disability Accumulation in Relapse-Onset MS but Not in Primary Progressive MSPLoS ONE2015122
33Incidence of stroke in young adults in Florence, Italy.Stroke1988115
34Cognitive reserve and cortical atrophy in multiple sclerosisNeurology2013113
35A prospective study on the natural history of multiple sclerosis: clues to the conduct and interpretation of clinical trialsJournal of the Neurological Sciences1999112
36Coping strategies, psychological variables and their relationship with quality of life in multiple sclerosisNeurological Sciences2009110
37A multicentre follow-up study of 1152 patients with myasthenia gravis in ItalyJournal of Neurology1990108
38Cognitive assessment and quantitative magnetic resonance metrics can help to identify benign multiple sclerosisNeurology2008104
39Ecology of Viruses Isolated from Sand Flies in Italy and Characterization of a New Phlebovirus (Arbia Virus)American Journal of Tropical Medicine and Hygiene1988102
40A prospective study on the prognosis of multiple sclerosisNeurological Sciences200094
41Neuropsychological and MRI measures predict short-term evolution in benign multiple sclerosisNeurology200990
42Effects of immunomodulatory treatment with subcutaneous interferon beta-1a oncognitive decline in mildly disabled patients with relapsing—remitting multiple sclerosisMultiple Sclerosis Journal201089
43Coping strategies, cognitive impairment, psychological variables and their relationship with quality of life in multiple sclerosisNeurological Sciences201087
44Long-Term Adherence to Interferon β Therapy in Relapsing-Remitting Multiple SclerosisEuropean Neurology200886
45The different apoptotic potential of the p53 codon 72 alleles increases with age and modulates in vivo ischaemia-induced cell deathCell Death and Differentiation200484
46Oxidative Stress and a Key Metabolic Enzyme in Alzheimer Brains, Cultured Cells, and an Animal Model of Chronic Oxidative DeficitsAnnals of the New York Academy of Sciences199982
47Pregnancy and fetal outcomes after Glatiramer Acetate exposure in patients with multiple sclerosis: a prospective observational multicentric studyBMC Neurology201282
48Impact of Natalizumab on Cognitive Performances and Fatigue in Relapsing Multiple Sclerosis: A Prospective, Open-Label, Two Years Observational StudyPLoS ONE201282
49EFFECT OF PHOSPHATIDYLSERINE ON ACETYLCHOLINE OUTPUT FROM THE CEREBRAL CORTEX OF THE RATJournal of Neurochemistry197980
50Epidural analgesia and cesarean delivery in multiple sclerosis post-partum relapses: the Italian cohort studyBMC Neurology201278