# | Title | Journal | Year | Citations |
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1 | Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein | Nature | 1995 | 2,463 |
2 | Drug Addiction, Dysregulation of Reward, and Allostasis | Neuropsychopharmacology | 2001 | 2,425 |
3 | Drugs of abuse: anatomy, pharmacology and function of reward pathways | Trends in Pharmacological Sciences | 1992 | 1,943 |
4 | Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection | Journal of Virology | 1994 | 1,731 |
5 | Cognitive and biological determinants of P300: an integrative review | Biological Psychology | 1995 | 1,417 |
6 | A second endogenous cannabinoid that modulates long-term potentiation | Nature | 1997 | 1,374 |
7 | Assessing antidepressant activity in rodents: recent developments and future needs | Trends in Pharmacological Sciences | 2002 | 1,373 |
8 | Molecular profile of reactive astrocytes—Implications for their role in neurologic disease | Neuroscience | 1993 | 1,371 |
9 | Meditation states and traits: EEG, ERP, and neuroimaging studies. | Psychological Bulletin | 2006 | 1,287 |
10 | Antiviral pressure exerted by HIV-l-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus | Nature Medicine | 1997 | 1,138 |
11 | Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor | Nature | 1995 | 1,033 |
12 | Induction of Bystander T Cell Proliferation by Viruses and Type I Interferon in Vivo | Science | 1996 | 1,013 |
13 | Transition from Moderate to Excessive Drug Intake: Change in Hedonic Set Point | | 1998 | 990 |
14 | P3a and P3b from typical auditory and visual stimuli | Clinical Neurophysiology | 1999 | 965 |
15 | Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6. | Proceedings of the National Academy of Sciences of the United States of America | 1993 | 957 |
16 | Neuroscience of Addiction | Neuron | 1998 | 894 |
17 | Corticotropin Releasing Factor Receptor 1–Deficient Mice Display Decreased Anxiety, Impaired Stress Response, and Aberrant Neuroendocrine Development | Neuron | 1998 | 839 |
18 | Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress | Nature Genetics | 2000 | 792 |
19 | Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: Role of anti-self (virus) immune response | Cell | 1991 | 757 |
20 | Dopamine activation of endogenous cannabinoid signaling in dorsal striatum | Nature Neuroscience | 1999 | 731 |
21 | The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases | Cell | 1995 | 702 |
22 | Central nervous system damage produced by expression of the HIV-1 coat protein gpl20 in transgenic mice | Nature | 1994 | 685 |
23 | Neurobiological Similarities in Depression and Drug Dependence: A Self-Medication Hypothesis | Neuropsychopharmacology | 1998 | 663 |
24 | Alcoholism: Allostasis and Beyond | Alcoholism: Clinical and Experimental Research | 2003 | 641 |
25 | Major expansion of CD8+ T cells with a predominant Vβ usage during the primary immune response to HIV | Nature | 1994 | 630 |
26 | Dramatic decreases in brain reward function during nicotine withdrawal | Nature | 1998 | 625 |
27 | Neuropsychology and neuropharmacology of P3a and P3b | International Journal of Psychophysiology | 2006 | 611 |
28 | Identification of -Dystroglycan as a Receptor for Lymphocytic Choriomeningitis Virus and Lassa Fever Virus | | 1998 | 609 |
29 | Drug dependence: stress and dysregulation of brain reward pathways | Drug and Alcohol Dependence | 1998 | 595 |
30 | Chemical characterization of a family of brain lipids that induce sleep | Science | 1995 | 589 |
31 | Anchorless Prion Protein Results in Infectious Amyloid Disease Without Clinical Scrapie | Science | 2005 | 585 |
32 | Corticotropin-releasing factor, norepinephrine, and stress | Biological Psychiatry | 1999 | 576 |
33 | Coronavirus Spike Proteins in Viral Entry and Pathogenesis | Virology | 2001 | 569 |
34 | Oral alcohol self-administration stimulates dopamine release in the rat nucleus accumbens: genetic and motivational determinants | Journal of Pharmacology and Experimental Therapeutics | 1993 | 562 |
35 | Neural Mechanisms of Drug Reinforcement | Annals of the New York Academy of Sciences | 1992 | 549 |
36 | Appetite-Suppressing Effects of Urocortin, a CRF-Related Neuropeptide | Science | 1996 | 548 |
37 | Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory | Nature Medicine | 2001 | 545 |
38 | Increase of extracellular corticotropin-releasing factor-like immunoreactivity levels in the amygdala of awake rats during restraint stress and ethanol withdrawal as measured by microdialysis | Journal of Neuroscience | 1995 | 542 |
39 | Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides | Science | 1993 | 541 |
40 | Molecular mimicry and immune‐mediated diseases | FASEB Journal | 1998 | 538 |
41 | Animal models of drug craving | Psychopharmacology | 1993 | 537 |
42 | Neurobiological mechanisms in the transition from drug use to drug dependence | Neuroscience and Biobehavioral Reviews | 2004 | 513 |
43 | A role for corticotropin releasing factor and urocortin in behavioral responses to stressors | Brain Research | 1999 | 498 |
44 | Neurocircuitry Targets in Ethanol Reward and Dependence | Alcoholism: Clinical and Experimental Research | 1998 | 494 |
45 | The neurobiology of drug addiction | Journal of Neuropsychiatry and Clinical Neurosciences | 1997 | 487 |
46 | Modulation of cocaine self-administration in the rat through D-3 dopamine receptors | Science | 1993 | 486 |
47 | Neuropeptide S | Neuron | 2004 | 478 |
48 | Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses | Cell | 1994 | 474 |
49 | Tyro-3 family receptors are essential regulators of mammalian spermatogenesis | Nature | 1999 | 458 |
50 | Ethanol Self-Administration Restores Withdrawal-Associated Deficiencies in Accumbal Dopamine and 5-Hydroxytryptamine Release in Dependent Rats | Journal of Neuroscience | 1996 | 411 |