# | Title | Journal | Year | Citations |
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1 | Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor | Cell | 2013 | 2,013 |
2 | Quantitative reactivity profiling predicts functional cysteines in proteomes | Nature | 2010 | 1,359 |
3 | Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells | Nature Biotechnology | 2012 | 1,347 |
4 | Protein Analysis by Shotgun/Bottom-up Proteomics | Chemical Reviews | 2013 | 1,171 |
5 | Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells | Nature | 2012 | 1,069 |
6 | New World Bats Harbor Diverse Influenza A Viruses | PLoS Pathogens | 2013 | 1,050 |
7 | Dynamic Changes in the Copy Number of Pluripotency and Cell Proliferation Genes in Human ESCs and iPSCs during Reprogramming and Time in Culture | Cell Stem Cell | 2011 | 819 |
8 | The promise and peril of chemical probes | Nature Chemical Biology | 2015 | 698 |
9 | Proteome-wide covalent ligand discovery in native biological systems | Nature | 2016 | 651 |
10 | Regulation of mTORC1 by amino acids | Trends in Cell Biology | 2014 | 649 |
11 | The biological impact of mass-spectrometry-based proteomics | Nature | 2007 | 638 |
12 | Mass spectrometry for proteomics | Current Opinion in Chemical Biology | 2008 | 603 |
13 | Endothelial Cells Are Central Orchestrators of Cytokine Amplification during Influenza Virus Infection | Cell | 2011 | 582 |
14 | Transcriptional Control of Mitochondrial Biogenesis and Function | Annual Review of Physiology | 2009 | 528 |
15 | Isobaric Labeling-Based Relative Quantification in Shotgun Proteomics | Journal of Proteome Research | 2014 | 520 |
16 | Bora and the Kinase Aurora A Cooperatively Activate the Kinase Plk1 and Control Mitotic Entry | Science | 2008 | 515 |
17 | Neutrophil Extracellular Traps Promote the Development and Progression of Liver Metastases after Surgical Stress | Cancer Research | 2016 | 491 |
18 | The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR | Nature | 2014 | 485 |
19 | Cryptochromes mediate rhythmic repression of the glucocorticoid receptor | Nature | 2011 | 481 |
20 | Molecular Architecture of the Human Pre-mRNA 3′ Processing Complex | Molecular Cell | 2009 | 475 |
21 | Identification of Long-Lived Proteins Reveals Exceptional Stability of Essential Cellular Structures | Cell | 2013 | 469 |
22 | Mass spectrometry in high-throughput proteomics: ready for the big time | Nature Methods | 2010 | 465 |
23 | PYR/PYL/RCAR family members are majorin‐vivoABI1 protein phosphatase 2C‐interacting proteins in Arabidopsis | Plant Journal | 2010 | 451 |
24 | Distinct Argonaute-Mediated 22G-RNA Pathways Direct Genome Surveillance in the C. elegans Germline | Molecular Cell | 2009 | 449 |
25 | From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations | Molecular Biology of the Cell | 2016 | 446 |
26 | ProLuCID: An improved SEQUEST-like algorithm with enhanced sensitivity and specificity | Journal of Proteomics | 2015 | 440 |
27 | A blood based 12-miRNA signature of Alzheimer disease patients | Genome Biology | 2013 | 438 |
28 | The Exopolysaccharide Matrix Modulates the Interaction between 3D Architecture and Virulence of a Mixed-Species Oral Biofilm | PLoS Pathogens | 2012 | 428 |
29 | The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding | Nature Immunology | 2009 | 417 |
30 | A bioinformatic assay for pluripotency in human cells | Nature Methods | 2011 | 410 |
31 | Glycan Microarrays for Decoding the Glycome | Annual Review of Biochemistry | 2011 | 395 |
32 | Isogenic Human iPSC Parkinson’s Model Shows Nitrosative Stress-Induced Dysfunction in MEF2-PGC1α Transcription | Cell | 2013 | 380 |
33 | High-efficiency labeling of sialylated glycoproteins on living cells | Nature Methods | 2009 | 370 |
34 | Human SLX4 Is a Holliday Junction Resolvase Subunit that Binds Multiple DNA Repair/Recombination Endonucleases | Cell | 2009 | 369 |
35 | Citrullination regulates pluripotency and histone H1 binding to chromatin | Nature | 2014 | 358 |
36 | Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia | Molecular Psychiatry | 2015 | 358 |
37 | Jmjd6 Catalyses Lysyl-Hydroxylation of U2AF65, a Protein Associated with RNA Splicing | Science | 2009 | 356 |
38 | Recurrent Variations in DNA Methylation in Human Pluripotent Stem Cells and Their Differentiated Derivatives | Cell Stem Cell | 2012 | 352 |
39 | Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome | Nature Chemical Biology | 2012 | 347 |
40 | LRRTM2 Interacts with Neurexin1 and Regulates Excitatory Synapse Formation | Neuron | 2009 | 338 |
41 | Chemical and Biological Approaches Synergize to Ameliorate Protein-Folding Diseases | Cell | 2008 | 332 |
42 | Ligand and Target Discovery by Fragment-Based Screening in Human Cells | Cell | 2017 | 330 |
43 | Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers | Immunity | 2014 | 323 |
44 | Global profiling of lysine reactivity and ligandability in the human proteome | Nature Chemistry | 2017 | 319 |
45 | Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway | Nature Medicine | 2012 | 315 |
46 | Production of hepatocyte-like cells from human pluripotent stem cells | Nature Protocols | 2013 | 292 |
47 | Enzyme Inhibitor Discovery by Activity-Based Protein Profiling | Annual Review of Biochemistry | 2014 | 292 |
48 | Protein post-translational modifications and regulation of pluripotency in human stem cells | Cell Research | 2014 | 282 |
49 | Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 281 |
50 | Epigenetic Characterization of the FMR1 Gene and Aberrant Neurodevelopment in Human Induced Pluripotent Stem Cell Models of Fragile X Syndrome | PLoS ONE | 2011 | 274 |