# | Title | Journal | Year | Citations |
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1 | Chronic inflammation in the etiology of disease across the life span | Nature Medicine | 2019 | 2,195 |
2 | Rheumatoid arthritis | Nature Reviews Disease Primers | 2018 | 1,441 |
3 | Noncovalent functionalization of carbon nanotubes for highly specific electronic biosensors | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 1,373 |
4 | Serum uric acid and cardiovascular disease: Recent developments, and where do they leave us? | American Journal of Medicine | 2005 | 302 |
5 | Diagnostic Criteria of Ulcerative Pyoderma Gangrenosum | JAMA Dermatology | 2018 | 292 |
6 | Pannexin-1 hemichannel–mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse | Blood | 2010 | 273 |
7 | Efficacy and safety of epratuzumab in patients with moderate/severe active systemic lupus erythematosus: results from EMBLEM, a phase IIb, randomised, double-blind, placebo-controlled, multicentre study | Annals of the Rheumatic Diseases | 2014 | 266 |
8 | Efficacy and safety of the selective co-stimulation modulator abatacept following 2 years of treatment in patients with rheumatoid arthritis and an inadequate response to anti-tumour necrosis factor therapy | Annals of the Rheumatic Diseases | 2008 | 232 |
9 | Rituximab inhibits structural joint damage in patients with rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitor therapies | Annals of the Rheumatic Diseases | 2009 | 228 |
10 | Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction | Nature Reviews Rheumatology | 2018 | 219 |
11 | Effect of Filgotinib vs Placebo on Clinical Response in Patients With Moderate to Severe Rheumatoid Arthritis Refractory to Disease-Modifying Antirheumatic Drug Therapy | JAMA - Journal of the American Medical Association | 2019 | 210 |
12 | An oral Syk kinase inhibitor in the treatment of rheumatoid arthritis: A three‐month randomized, placebo‐controlled, phase II study in patients with active rheumatoid arthritis that did not respond to biologic agents | Arthritis and Rheumatism | 2011 | 190 |
13 | Antigen-specific T cell–mediated gene therapy in collagen-induced arthritis | Journal of Clinical Investigation | 2001 | 171 |
14 | Epigenetic signature of PD-1+ TCF1+ CD8 T cells that act as resource cells during chronic viral infection and respond to PD-1 blockade | Proceedings of the National Academy of Sciences of the United States of America | 2019 | 157 |
15 | Clinical and pathological evolution of giant cell arteritis: a prospective study of follow-up temporal artery biopsies in 40 treated patients | Modern Pathology | 2017 | 148 |
16 | Are COX-2 inhibitors preferable to non-selective non-steroidal anti-inflammatory drugs in patients with risk of cardiovascular events taking low-dose aspirin? | Lancet, The | 2007 | 145 |
17 | Role of CD4 and CD8 in T Cell Activation and Differentiation | Advances in Immunology | 1993 | 144 |
18 | The relative toxicity of nonsteroidal antiinflammatory drugs | Arthritis and Rheumatism | 1991 | 136 |
19 | Identifying core domains to assess flare in rheumatoid arthritis: an OMERACT international patient and provider combined Delphi consensus | Annals of the Rheumatic Diseases | 2012 | 131 |
20 | Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by Treg depletion | Blood | 2009 | 121 |
21 | IFN-γ and IL-17: the two faces of T-cell pathology in giant cell arteritis | Current Opinion in Rheumatology | 2011 | 120 |
22 | Portable, one-step, and rapid GMR biosensor platform with smartphone interface | Biosensors and Bioelectronics | 2016 | 111 |
23 | A 24-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study of the Efficacy of Oral SCIO-469, a p38 Mitogen-activated Protein Kinase Inhibitor, in Patients with Active Rheumatoid Arthritis | Journal of Rheumatology | 2011 | 108 |
24 | High-throughput sequencing of natively paired antibody chains provides evidence for original antigenic sin shaping the antibody response to influenza vaccination | Clinical Immunology | 2014 | 108 |
25 | Quantitative Tissue Characterization of Infarct Core and Border Zone in Patients With Ischemic Cardiomyopathy by Magnetic Resonance Is Associated With Future Cardiovascular Events | Journal of the American College of Cardiology | 2010 | 104 |
26 | Blood autoantibody and cytokine profiles predict response to anti-tumor necrosis factor therapy in rheumatoid arthritis | Arthritis Research and Therapy | 2009 | 99 |
27 | A pilot study of tumor necrosis factor inhibition in erosive/inflammatory osteoarthritis of the hands | Journal of Rheumatology | 2007 | 97 |
28 | Adalimumab long-term safety: infections, vaccination response and pregnancy outcomes in patients with rheumatoid arthritis | Annals of the Rheumatic Diseases | 2017 | 94 |
29 | A phase II, double-blind, randomised, placebo-controlled study of BMS945429 (ALD518) in patients with rheumatoid arthritis with an inadequate response to methotrexate | Annals of the Rheumatic Diseases | 2012 | 87 |
30 | Hypertonic stress regulates T cell function via pannexin-1 hemichannels and P2X receptors | Journal of Leukocyte Biology | 2010 | 86 |
31 | Non-progressing cancer patients have persistent B cell responses expressing shared antibody paratopes that target public tumor antigens | Clinical Immunology | 2018 | 86 |
32 | Breaking self-tolerance in nonobese diabetic mice. | Journal of Experimental Medicine | 1996 | 84 |
33 | Fenebrutinib Versus Placebo or Adalimumab in Rheumatoid Arthritis: A Randomized, Double‐Blind, Phase II Trial | Arthritis and Rheumatology | 2020 | 83 |
34 | Self-antigen recognition by follicular lymphoma B-cell receptors | Blood | 2012 | 81 |
35 | Self-report was a viable method for obtaining health care utilization data in community-dwelling seniors | Journal of Clinical Epidemiology | 2005 | 74 |
36 | Immune Aging and Rheumatoid Arthritis | Rheumatic Disease Clinics of North America | 2010 | 71 |
37 | Hallmarks of the aging T‐cell system | FEBS Journal | 2021 | 70 |
38 | A Novel E3 Ubiquitin Ligase Substrate Screen Identifies Rho Guanine Dissociation Inhibitor as a Substrate of Gene Related to Anergy in Lymphocytes | Journal of Immunology | 2006 | 69 |
39 | A systematic review and meta-analysis to inform cancer screening guidelines in idiopathic inflammatory myopathies | Rheumatology | 2021 | 69 |
40 | Clinical presentation and evaluation of dermatomyositis | Indian Journal of Dermatology | 2012 | 69 |
41 | Epstein-Barr virus and multiple sclerosis | Science | 2022 | 68 |
42 | Murine CD4+CD25+ Regulatory T Cells Fail to Undergo Chromatin Remodeling Across the Proximal Promoter Region of the IL-2 Gene | Journal of Immunology | 2004 | 66 |
43 | Tabalumab, an anti-BAFF monoclonal antibody, in patients with active rheumatoid arthritis with an inadequate response to TNF inhibitors | Annals of the Rheumatic Diseases | 2013 | 66 |
44 | T Cell–Macrophage Interactions and Granuloma Formation in Vasculitis | Frontiers in Immunology | 2014 | 65 |
45 | AIRE expression controls the peripheral selection of autoreactive B cells | Science Immunology | 2019 | 65 |
46 | Revealing the specificity of regulatory T cells in murine autoimmune diabetes | Proceedings of the National Academy of Sciences of the United States of America | 2018 | 64 |
47 | An integrated analysis of five double-blind, randomized controlled trials evaluating the safety and efficacy of a hyaluronan product for intra-articular injection in osteoarthritis of the knee | Osteoarthritis and Cartilage | 2006 | 63 |
48 | Hospitalizations and mortality in systemic sclerosis: results from the Nationwide Inpatient Sample | Rheumatology | 2007 | 63 |
49 | Improvements in patient-reported outcomes with apremilast, an oral phosphodiesterase 4 inhibitor, in the treatment of moderate to severe psoriasis: results from a phase IIb randomized, controlled study | Health and Quality of Life Outcomes | 2013 | 63 |
50 | Identification of anticitrullinated protein antibody reactivities in a subset of anti-CCP-negative rheumatoid arthritis: association with cigarette smoking and HLA-DRB1 ‘shared epitope’ alleles | Annals of the Rheumatic Diseases | 2015 | 62 |