| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 3 | Quantification of biofilm in microtiter plates: overview of testing conditions and practical recommendations for assessment of biofilm production by staphylococci | Apmis | 2007 | 1,407 |
| 4 | Everolimus for the treatment of advanced, non-functional neuroendocrine tumours of the lung or gastrointestinal tract (RADIANT-4): a randomised, placebo-controlled, phase 3 study | Lancet, The | 2016 | 962 |
| 5 | Artificial neural networks in medical diagnosis | Journal of Applied Biomedicine | 2013 | 629 |
| 6 | Cellular Mechanotransduction: From Tension to Function | Frontiers in Physiology | 2018 | 594 |
| 7 | Reduced-intensity chemotherapy and PET-guided radiotherapy in patients with advanced stage Hodgkin's lymphoma (HD15 trial): a randomised, open-label, phase 3 non-inferiority trial | Lancet, The | 2012 | 564 |
| 8 | Isavuconazole treatment for mucormycosis: a single-arm open-label trial and case-control analysis | Lancet Infectious Diseases, The | 2016 | 528 |
| 9 | Interrogating open issues in cancer precision medicine with patient-derived xenografts | Nature Reviews Cancer | 2017 | 527 |
| 10 | Clinical picture and treatment of 2212 patients with common variable immunodeficiency | Journal of Allergy and Clinical Immunology | 2014 | 512 |
| 11 | Increasing incidence of colorectal cancer in young adults in Europe over the last 25 years | Gut | 2019 | 463 |
| 12 | TGF-β – an excellent servant but a bad master | Journal of Translational Medicine | 2012 | 390 |
| 13 | Muscle-specific microRNAs in skeletal muscle development | Developmental Biology | 2016 | 389 |
| 14 | Cannabinoid receptors 1 and 2 (CB1 and CB2), their distribution, ligands and functional involvement in nervous system structures — A short review | Pharmacology Biochemistry and Behavior | 2008 | 367 |
| 15 | Quaternary protoberberine alkaloids | Phytochemistry | 2007 | 366 |
| 16 | Consensus recommendations for the diagnosis and clinical management of Rosai-Dorfman-Destombes disease | Blood | 2018 | 335 |
| 17 | Personalized therapy in multiple myeloma according to patient age and vulnerability: a report of the European Myeloma Network (EMN) | Blood | 2011 | 309 |
| 18 | MicroRNAs in colorectal cancer: translation of molecular biology into clinical application | Molecular Cancer | 2009 | 302 |
| 19 | Effect of tumor microenvironment on pathogenesis of the head and neck squamous cell carcinoma: a systematic review | Molecular Cancer | 2019 | 288 |
| 20 | Simplified protocol for flow cytometry analysis of fluorescently labeled exosomes and microvesicles using dedicated flow cytometer | Journal of Extracellular Vesicles | 2015 | 287 |
| 21 | Prevalence of COVID-19 Vaccine Side Effects among Healthcare Workers in the Czech Republic | Journal of Clinical Medicine | 2021 | 251 |
| 22 | Effect of Intra-arrest Transport, Extracorporeal Cardiopulmonary Resuscitation, and Immediate Invasive Assessment and Treatment on Functional Neurologic Outcome in Refractory Out-of-Hospital Cardiac Arrest | JAMA - Journal of the American Medical Association | 2022 | 242 |
| 23 | Biphasic Effects of Anandamide | Pharmacology Biochemistry and Behavior | 1998 | 240 |
| 24 | EFNS‐ENS Guidelines on the diagnosis and management of disorders associated with dementia | European Journal of Neurology | 2012 | 239 |
| 25 | Body Mass Index and Mortality in Acutely Decompensated Heart Failure Across the World | Journal of the American College of Cardiology | 2014 | 213 |
| 26 | Cannabinoids and Cytochrome P450 Interactions | Current Drug Metabolism | 2016 | 205 |
| 27 | Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd | Nature Communications | 2016 | 204 |
| 28 | Sleep scoring using artificial neural networks | Sleep Medicine Reviews | 2012 | 185 |
| 29 | A Complex Role for FGF-2 in Self-Renewal, Survival, and Adhesion of Human Embryonic Stem Cells | Stem Cells | 2009 | 184 |
| 30 | Treponema pallidum, the syphilis spirochete: making a living as a stealth pathogen | Nature Reviews Microbiology | 2016 | 184 |
| 31 | B‐cell receptor signalling and its crosstalk with other pathways in normal and malignant cells | European Journal of Haematology | 2015 | 173 |
| 32 | Nasopharyngeal carcinoma: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up† | Annals of Oncology | 2021 | 165 |
| 33 | Monoallelic and biallelic inactivation of TP53 gene in chronic lymphocytic leukemia: selection, impact on survival, and response to DNA damage | Blood | 2009 | 164 |
| 34 | Cytogenetic complexity in chronic lymphocytic leukemia: definitions, associations, and clinical impact | Blood | 2019 | 164 |
| 35 | Soluble BAFF Levels Inversely Correlate with Peripheral B Cell Numbers and the Expression of BAFF Receptors | Journal of Immunology | 2012 | 155 |
| 36 | Atlas of the normal intracranial electroencephalogram: neurophysiological awake activity in different cortical areas | Brain | 2018 | 155 |
| 37 | Mammalian DIS3L2 exoribonuclease targets the uridylated precursors of let-7 miRNAs | Rna | 2013 | 153 |
| 38 | Higher spermidine intake is linked to lower mortality: a prospective population-based study | American Journal of Clinical Nutrition | 2018 | 150 |
| 39 | Side Effects of mRNA-Based and Viral Vector-Based COVID-19 Vaccines among German Healthcare Workers | Biology | 2021 | 150 |
| 40 | MiR‐195, miR‐196b, miR‐181c, miR‐21 expression levels and O‐6‐methylguanine‐DNA methyltransferase methylation status are associated with clinical outcome in glioblastoma patients | Cancer Science | 2011 | 145 |
| 41 | Randomized Comparison of Tenofovir Disoproxil Fumarate vs Emtricitabine and Tenofovir Disoproxil Fumarate in Patients With Lamivudine-Resistant Chronic Hepatitis B | Gastroenterology | 2014 | 145 |
| 42 | Exacerbation of substrate toxicity by IPTG in Escherichia coli BL21(DE3) carrying a synthetic metabolic pathway | Microbial Cell Factories | 2015 | 145 |
| 43 | Comparison of the low-frequency magnetic field effects on bacteria Escherichia coli, Leclercia adecarboxylata and Staphylococcus aureus | Bioelectrochemistry | 2004 | 144 |
| 44 | Proteasome inhibitors – molecular basis and current perspectives in multiple myeloma | Journal of Cellular and Molecular Medicine | 2014 | 144 |
| 45 | The influence of Congo red on the cell wall and (1 → 3)-β-d-glucan microfibril biogenesis in Saccharomyces cerevisiae | Archives of Microbiology | 1992 | 141 |
| 46 | Serum-based microRNA signatures in early diagnosis and prognosis prediction of colon cancer | Carcinogenesis | 2016 | 141 |
| 47 | Choroid plexus and the blood–cerebrospinal fluid barrier in disease | Fluids and Barriers of the CNS | 2020 | 141 |
| 48 | ABTS and DPPH methods as a tool for studying antioxidant capacity of spring barley and malt | Journal of Cereal Science | 2017 | 139 |
| 49 | Origin of modern syphilis and emergence of a pandemic Treponema pallidum cluster | Nature Microbiology | 2017 | 138 |
| 50 | Cell segmentation methods for label-free contrast microscopy: review and comprehensive comparison | BMC Bioinformatics | 2019 | 137 |
