| # | Title | Journal | Year | Citations |
|---|
| 1 | Elevated Circulating Levels of Tumor Necrosis Factor in Severe Chronic Heart Failure | New England Journal of Medicine | 1990 | 2,370 |
| 2 | Profound Peripheral Insulin Resistance, Independent of Obesity, in Polycystic Ovary Syndrome | Diabetes | 1989 | 1,697 |
| 3 | Coarctation of the aorta. Long-term follow-up and prediction of outcome after surgical correction. | Circulation | 1989 | 671 |
| 4 | Neurohormonal interactions and adaptations in congestive heart failure. | Circulation | 1988 | 564 |
| 5 | Evidence for Distinctive and Intrinsic Defects in Insulin Action in Polycystic Ovary Syndrome | Diabetes | 1992 | 459 |
| 6 | Prognostic importance of atrial natriuretic peptide in patients with chronic heart failure | Journal of the American College of Cardiology | 1989 | 342 |
| 7 | Severe recurrent cholestatic hepatitis C following orthotopic liver transplantation | Hepatology | 1996 | 306 |
| 8 | Hormone-electrolyte interactions in the pathogenesis of lethal cardiac arrhythmias in patients with congestive heart failure: Basis of a new physiologic approach to control of arrhythmia | American Journal of Medicine | 1986 | 302 |
| 9 | Biliary physiology in rats with bile ductular cell hyperplasia. Evidence for a secretory function of proliferated bile ductules. | Journal of Clinical Investigation | 1988 | 297 |
| 10 | Isolated atrial septal defect with pulmonary vascular obstructive disease--long-term follow-up and prediction of outcome after surgical correction. | Circulation | 1987 | 284 |
| 11 | MECHANISMS OF LYSOSOMAL ENZYME RELEASE FROM HUMAN LEUKOCYTES | Journal of Cell Biology | 1973 | 270 |
| 12 | Infective Endocarditis in the U.S., 1998–2009: A Nationwide Study | PLoS ONE | 2013 | 259 |
| 13 | Origin, pattern, and mechanism of bile duct proliferation following biliary obstruction in the rat | Gastroenterology | 1990 | 216 |
| 14 | Complications of Colonoscopy and Flexible Sigmoidoscopy | Gastrointestinal Endoscopy Clinics of North America | 1996 | 214 |
| 15 | The Energy Cost of the Metabolism of Drugs, Including Ethanol | Pharmacology | 1972 | 211 |
| 16 | Expression of tissue factor procoagulant activity: regulation by cytosolic calcium. | Proceedings of the National Academy of Sciences of the United States of America | 1990 | 207 |
| 17 | Eisenmengerʼs Syndrome and Pregnancy | Obstetrical and Gynecological Survey | 1979 | 206 |
| 18 | Benign and malignant colorectal strictures in ulcerative colitis. | Gut | 1992 | 196 |
| 19 | Ulcerative colitis practice guidelines in adults. American College of Gastroenterology, Practice Parameters Committee | American Journal of Gastroenterology | 1997 | 186 |
| 20 | Use of a perforated balloon catheter to deliver concentrated heparin into the wall of the normal canine artery | Journal of the American College of Cardiology | 1990 | 185 |
| 21 | Sustained ventricular tachycardia associated with sarcoidosis: Assessment of the underlying cardiac anatomy and the prospective utility of programmed ventricular stimulation, drug therapy and an implantable antitachycardia device | Journal of the American College of Cardiology | 1991 | 184 |
| 22 | Fungal infection in acute leukemia | Cancer | 1972 | 182 |
| 23 | Insulin administration alters gonadal steroid metabolism independent of changes in gonadotropin secretion in insulin-resistant women with the polycystic ovary syndrome. | Journal of Clinical Investigation | 1989 | 182 |
| 24 | Uptake of oleate by isolated rat adipocytes is mediated by a 40-kDa plasma membrane fatty acid binding protein closely related to that in liver and gut. | Proceedings of the National Academy of Sciences of the United States of America | 1988 | 172 |
| 25 | SHEEP RED CELL BINDING TO HUMAN LYMPHOCYTES TREATED WITH NEURAMINIDASE; ENHANCEMENT OF T CELL BINDING AND IDENTIFICATION OF A SUBPOPULATION OF B CELLS | Journal of Experimental Medicine | 1973 | 165 |
| 26 | The Impact of Obesity and Chronic Hyperinsulinemia on Gonadotropin Release and Gonadal Steroid Secretion in the Polycystic Ovary Syndrome* | Journal of Clinical Endocrinology and Metabolism | 1988 | 157 |
| 27 | Optimal bandpass filters for time-domain analysis of the signal-averaged electrocardiogram | American Journal of Cardiology | 1987 | 151 |
| 28 | The ?stone heart?: A challenge to the biochemist | American Journal of Cardiology | 1972 | 139 |
| 29 | Bloodstream infections in the elderly | American Journal of Medicine | 1989 | 134 |
| 30 | In vitro and in vivo studies of cellular immunity in alcoholic cirrhosis | The American Journal of Digestive Diseases | 1974 | 133 |
| 31 | Vasodilator and inotropic therapy for severe chronic heart failure: Passion and skepticism | Journal of the American College of Cardiology | 1983 | 133 |
| 32 | Mechanisms of Cellular Uptake of Free Fatty Acids | Annual Review of Nutrition | 1989 | 132 |
| 33 | The tissue factor pathway of blood coagulation | Seminars in Hematology | 1992 | 131 |
| 34 | Human tissue factor contains thioester-linked palmitate and stearate on the cytoplasmic half-cystine | Biochemistry | 1988 | 124 |
| 35 | Hepatic Collagen Metabolism: Effect of Alcohol Consumption in Rats and Baboons | Science | 1972 | 122 |
| 36 | The liver in the acquired immunodeficiency syndrome: A clinical and histologic study | Hepatology | 1985 | 118 |
| 37 | Vasodilator and inotropic drugs for the treatment of chronic heart failure: Distinguishing hype from hope | Journal of the American College of Cardiology | 1988 | 118 |
| 38 | Relation between serum sodium concentration and the hemodynamic and clinical responses to converting enzyme inhibition with captopril in severe heart failure | Journal of the American College of Cardiology | 1984 | 117 |
| 39 | Deficiency of Vitamin B12-Binding Alpha Globulin in Two Brothers | Blood | 1969 | 115 |
| 40 | Hemoglobin Biosynthesis in Murine Virus-induced Leukemic Cells In Vitro: Structure and Amounts of Globin Chains Produced | Blood | 1972 | 114 |
| 41 | Determinants of collateral filling observed during sudden controlled coronary artery occlusion in human subjects | Journal of the American College of Cardiology | 1989 | 114 |
| 42 | Big ACTH: Conversion to Biologically Active ACTH by Trypsin | Journal of Clinical Endocrinology and Metabolism | 1974 | 112 |
| 43 | Hemoglobin synthesis in murine virus-induced leukemic cells in vitro. III. Effects of 5-bromo-2?-deoxyuridine, dimethylformamide and dimethylsulfoxide | Journal of Cellular Physiology | 1973 | 108 |
| 44 | Pyomyositis in patients with the human immunodeficiency virus: An unusual form of disseminated bacterial infection | American Journal of Medicine | 1991 | 104 |
| 45 | Myocardial infarction due to coronary atherosclerosis in three young adults with systemic lupus erythematosus | American Journal of Cardiology | 1975 | 99 |
| 46 | Dose requirements of hydralazine in patients with severe chronic congestive heart failure | American Journal of Cardiology | 1980 | 99 |
| 47 | Calcium-membrane interactions in the myocardium: Effects of ouabain, epinephrine and 3′, 5′-cyclic adenosine monophosphate | American Journal of Cardiology | 1973 | 97 |
| 48 | Usefulness of antithrombotic therapy in resting angina pectoris or non-Q-wave myocardial infarction in preventing death and myocardial infarction (a pilot study from the antithrombotic therapy in acute coronary syndromes study group) | American Journal of Cardiology | 1990 | 97 |
| 49 | Radioisotopic Assay for Measurement of Serum Folate Levels | Blood | 1971 | 96 |
| 50 | Acanthosis Nigricans, Insulin Action, and Hyperandrogenism: Clinical, Histological, and Biochemical Findings* | Journal of Clinical Endocrinology and Metabolism | 1991 | 94 |
