| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update | Nucleic Acids Research | 2018 | 3,003 |
| 3 | Phase transitions in the assembly of multivalent signalling proteins | Nature | 2012 | 1,938 |
| 4 | Frontiers, Opportunities, and Challenges in Biochemical and Chemical Catalysis of CO2 Fixation | Chemical Reviews | 2013 | 1,786 |
| 5 | The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update | Nucleic Acids Research | 2016 | 1,751 |
| 6 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 7 | Expanded encyclopaedias of DNA elements in the human and mouse genomes | Nature | 2020 | 1,252 |
| 8 | Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation | Journal of Cell Biology | 2009 | 1,230 |
| 9 | PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps | Journal of Experimental Medicine | 2010 | 1,175 |
| 10 | ALTERATION OF NUCLEOSOME STRUCTURE AS A MECHANISM OF TRANSCRIPTIONAL REGULATION | Annual Review of Biochemistry | 1998 | 1,061 |
| 11 | Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population | Nature | 2006 | 982 |
| 12 | Nucleosome positioning and gene regulation: advances through genomics | Nature Reviews Genetics | 2009 | 915 |
| 13 | Colicin Biology | Microbiology and Molecular Biology Reviews | 2007 | 902 |
| 14 | Non-Heme Fe(IV)–Oxo Intermediates | Accounts of Chemical Research | 2007 | 866 |
| 15 | SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2 | Cell | 2020 | 860 |
| 16 | Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data | Nature Biotechnology | 2013 | 846 |
| 17 | Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex | Science | 1994 | 824 |
| 18 | Diabetes primes neutrophils to undergo NETosis, which impairs wound healing | Nature Medicine | 2015 | 824 |
| 19 | Methods of integrating data to uncover genotype–phenotype interactions | Nature Reviews Genetics | 2015 | 803 |
| 20 | Topologically associating domains are stable units of replication-timing regulation | Nature | 2014 | 779 |
| 21 | The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen | Nature Medicine | 2000 | 755 |
| 22 | Recent functional insights into the role of (p)ppGpp in bacterial physiology | Nature Reviews Microbiology | 2015 | 703 |
| 23 | Comprehensive Genome-wide Protein-DNA Interactions Detected at Single-Nucleotide Resolution | Cell | 2011 | 684 |
| 24 | ATP-Dependent Chromatin-Remodeling Complexes | Molecular and Cellular Biology | 2000 | 661 |
| 25 | The genome of Theobroma cacao | Nature Genetics | 2011 | 656 |
| 26 | The First Direct Characterization of a High-Valent Iron Intermediate in the Reaction of an α-Ketoglutarate-Dependent Dioxygenase: A High-Spin Fe(IV) Complex in Taurine/α-Ketoglutarate Dioxygenase (TauD) from Escherichia coli | Biochemistry | 2003 | 654 |
| 27 | Nucleosome organization in the Drosophila genome | Nature | 2008 | 636 |
| 28 | Translational and rotational settings of H2A.Z nucleosomes across the Saccharomyces cerevisiae genome | Nature | 2007 | 610 |
| 29 | A barrier nucleosome model for statistical positioning of nucleosomes throughout the yeast genome | Genome Research | 2008 | 591 |
| 30 | Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication | Cell | 2010 | 591 |
| 31 | ING Tumor Suppressor Proteins Are Critical Regulators of Chromatin Acetylation Required for Genome Expression and Perpetuation | Molecular Cell | 2006 | 589 |
| 32 | Identification and Distinct Regulation of Yeast TATA Box-Containing Genes | Cell | 2004 | 578 |
| 33 | Prokaryotic carbonic anhydrases | FEMS Microbiology Reviews | 2000 | 566 |
| 34 | Shewanella oneidensis MR-1 nanowires are outer membrane and periplasmic extensions of the extracellular electron transport components | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 531 |
| 35 | Structural and Functional Conservation of the NuA4 Histone Acetyltransferase Complex from Yeast to Humans | Molecular and Cellular Biology | 2004 | 516 |
| 36 | Mechanism of inhibition of HIV-1 reverse transcriptase by nonnucleoside inhibitors | Science | 1995 | 509 |
| 37 | Ten Simple Rules for Reproducible Computational Research | PLoS Computational Biology | 2013 | 509 |
| 38 | A Genome-Wide Housekeeping Role for TFIID and a Highly Regulated Stress-Related Role for SAGA in Saccharomyces cerevisiae | Molecular Cell | 2004 | 502 |
| 39 | Neutrophil Extracellular Traps Promote the Development and Progression of Liver Metastases after Surgical Stress | Cancer Research | 2016 | 491 |
| 40 | The diverse functions of histone acetyltransferase complexes | Trends in Genetics | 2003 | 485 |
| 41 | Function and Selectivity of Bromodomains in Anchoring Chromatin-Modifying Complexes to Promoter Nucleosomes | Cell | 2002 | 483 |
| 42 | Carbonic Anhydrase: New Insights for an Ancient Enzyme | Journal of Biological Chemistry | 2001 | 478 |
| 43 | Genome-wide structure and organization of eukaryotic pre-initiation complexes | Nature | 2012 | 475 |
| 44 | Transcriptional activators direct histone acetyltransferase complexes to nucleosomes | Nature | 1998 | 471 |
| 45 | Prokaryotic photosynthesis and phototrophy illuminated | Trends in Microbiology | 2006 | 470 |
| 46 | A Subfamily of P-Type ATPases with Aminophospholipid Transporting Activity | Science | 1996 | 462 |
| 47 | Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 453 |
| 48 | Unexpected Diversity and Complexity of the Guerrero Negro Hypersaline Microbial Mat | Applied and Environmental Microbiology | 2006 | 435 |
| 49 | Mechanisms of action of ribavirin against distinct viruses | Reviews in Medical Virology | 2006 | 428 |
| 50 | A Subset of TAFIIs Are Integral Components of the SAGA Complex Required for Nucleosome Acetylation and Transcriptional Stimulation | Cell | 1998 | 411 |
