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Top Articles

#TitleJournalYearCitations
1Guidelines for the use and interpretation of assays for monitoring autophagyAutophagy20123,122
2Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibilityNature Genetics2014959
3Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-KinaseJournal of Biological Chemistry2010942
4Worldwide prevalence and risk factors for myopiaOphthalmic and Physiological Optics2012624
5Risk Factors for Severe Outcomes following 2009 Influenza A (H1N1) Infection: A Global Pooled AnalysisPLoS Medicine2011581
6Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east AsiansNature Genetics2012545
7Efficacy Comparison of 16 Interventions for Myopia Control in ChildrenOphthalmology2016521
8Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east AsiansNature Genetics2011516
9Autologous Bone Marrow–Derived Mesenchymal Stem Cells Versus Autologous Chondrocyte ImplantationAmerican Journal of Sports Medicine2010510
10Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility lociNature Genetics2011481
11A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinomaNature Genetics2010453
12Autophagy and oxidative stress associated with gold nanoparticlesBiomaterials2010449
13Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk: A Meta-Analysis of 218,166 Adults and 19,268 ChildrenPLoS Medicine2011446
14Pressurized hot water extraction (PHWE)Journal of Chromatography A2010439
15Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian menDiabetologia2010405
16Microdevice for the isolation and enumeration of cancer cells from bloodBiomedical Microdevices2009346
17Autophagic cell death: Loch Ness monster or endangered species?Autophagy2011298
18A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4BNature Genetics2010245
19Myopia-Related Optic Disc and Retinal Changes in Adolescent Children from SingaporeOphthalmology2011217
20Revisiting Mendelian disorders through exome sequencingHuman Genetics2011206
21Activation of the PI3K-Akt-mTOR signaling pathway promotes necrotic cell death via suppression of autophagyAutophagy2009200
22Antioxidant activity and profiles of common fruits in SingaporeFood Chemistry2010200
23Identification of New Genetic Risk Variants for Type 2 DiabetesPLoS Genetics2010193
24The pursuit of genome-wide association studies: where are we now?Journal of Human Genetics2010191
25Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1Nature Genetics2011181
26Application of Advanced Statistics in Ophthalmology2011181
27A study on Singaporean women's acceptance of using mobile phones to seek health informationInternational Journal of Medical Informatics2011179
28The 5p15.33 Locus Is Associated with Risk of Lung Adenocarcinoma in Never-Smoking Females in AsiaPLoS Genetics2010168
29zVAD-induced necroptosis in L929 cells depends on autocrine production of TNFα mediated by the PKC–MAPKs–AP-1 pathwayCell Death and Differentiation2011160
30Exome sequencing: Dual role as a discovery and diagnostic toolAnnals of Neurology2012157
31Body Mass Index and Diabetes in Asia: A Cross-Sectional Pooled Analysis of 900,000 Individuals in the Asia Cohort ConsortiumPLoS ONE2011154
32Antioxidant activity and profiles of common vegetables in SingaporeFood Chemistry2010152
33Using Instrument-Defined Health State Transitions to Estimate Minimally Important Differences for Four Preference-Based Health-Related Quality of Life InstrumentsMedical Care2010150
34Progression of Parkinson's disease as evaluated by Hoehn and Yahr stage transition timesMovement Disorders2010150
35Enhancement of the capabilities of liquid chromatography–mass spectrometry with derivatization: General principles and applicationsMass Spectrometry Reviews2011135
36Real-Time Epidemic Monitoring and Forecasting of H1N1-2009 Using Influenza-Like Illness from General Practice and Family Doctor Clinics in SingaporePLoS ONE2010133
37Family history, near work, outdoor activity, and myopia in Singapore Chinese preschool childrenBritish Journal of Ophthalmology2010132
38Transferability of Type 2 Diabetes Implicated Loci in Multi-Ethnic Cohorts from Southeast AsiaPLoS Genetics2011131
39Ocular Component Growth Curves among Singaporean Children with Different Refractive Error Status2010121
40Breast cancer in a multi-ethnic Asian setting: Results from the Singapore–Malaysia hospital-based breast cancer registryBreast2011115
41Statistical Analysis of Illness–Death Processes and Semicompeting Risks DataBiometrics2010110
42Studying the epigenome using next generation sequencingJournal of Medical Genetics2011108
43Insights into the Genetic Architecture of Early Stage Age-Related Macular Degeneration: A Genome-Wide Association Study Meta-AnalysisPLoS ONE2013108
44Smoking as an independent risk factor for hepatocellular carcinoma: the Singapore Chinese Health StudyBritish Journal of Cancer2011107
45Cucurbitacin induces autophagy through mitochondrial ROS production which counteracts to limit caspase-dependent apoptosisAutophagy2012107
46Building Caries Risk Assessment Models for ChildrenJournal of Dental Research2010104
47Ethnicity Modifies the Relationships of Insulin Resistance, Inflammation, and Adiponectin With Obesity in a Multiethnic Asian PopulationDiabetes Care2011104
48Inhibition of the JAK-STAT3 pathway by andrographolide enhances chemosensitivity of cancer cells to doxorubicinBiochemical Pharmacology2010103
49Skin cancer trends among Asians living in Singapore from 1968 to 2006Journal of the American Academy of Dermatology200999
50Dietary Patterns and Incident Type 2 Diabetes in Chinese Men and WomenDiabetes Care201199